24 completed, 8 unknown, 4 not yet recruiting, 4 recruiting. 45 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 45 | Completed 24, Unknown 8, Not yet recruiting 4, Recruiting 4, Terminated 2, Withdrawn 2, Enrolling by invitation 1 |
Follow Neurodevelopmental Disorders: new trials by email Literature Review of Neurodevelopmental Disorders trials Research Report on Neurodevelopmental Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aprepitant for the Treatment of CLIFAHDD Aprepitant Powder for Oral Suspension - CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay | Early Phase 1 | Recruiting | The University of Texas Health Science Center at San Antonio | 5 | 2026-10-31 | 2026-10-05 |
| Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder Prednisone, Placebo - Autism Spectrum Disorder, Autism Spectrum Disorders | Early Phase 1 | Recruiting | Christopher John McDougle, M.D. | 32 | 2026-08-01 | 2026-08-19 |
| VGN-Ex05e in Patients With Autism Spectrum Disorder Associated With Severe Self-Injurious and Aggressive Behaviors VGN-Ex05e - Autism Spectrum Disorder | Early Phase 1 | Not yet recruiting | Shanghai Jiao Tong University School of Medicine | 6 | 2026-04-01 | 2026-02-25 |
| Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design Pickleball Program (Community-Based) - Autism Spectrum Disorder | Early Phase 1 | Recruiting | Penn State University | 50 | 2026-02-02 | 2026-02-25 |
| Measurement of Treatment Effects Psychotropic medication (at discretion of psychiatrist), Behavioral therapy - Challenging Behavior, Autism Spectrum Disorder | Early Phase 1 | Not yet recruiting | Matthew J O'Brien, PhD, BCBA-D | 20 | 2025-06-15 | 2025-06-17 |
| Evaluating the Efficacy of Atomoxetine in Reducing Primary Nocturnal Enuresis in Children With ADHD: A Randomized, Placebo-Controlled Study Atomoxetine, Placebo - ADHD, Primary Nocturnal Enuresis | Early Phase 1 | Not yet recruiting | Tanta University | 100 | 2025-02-28 | 2025-02-27 |
| Clinical Trial of the Dual Vector Base Editor for the Treatment of the CHD3-R1025W Mutation Dual vector DNA base editor - Developmental Delay Disorder, Intellectual Disability | Early Phase 1 | Terminated | Yongguo Yu | 1 | 2025-02-19 | 2026-07-30 |
| Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues Decompartmentalization Framework, Liquid Herbal TInctures, Mental Imagery - Schizoaffective Disorder, Bipolar Type, Bipolar Disorder | Early Phase 1 | Unknown | The Essence of Integrative Health and Medicine Practice | 30 | 2024-10-10 | 2024-08-12 |
| Promoting Playfulness Parent Education - Promoting Playfulness - Developmental Delay (Disorder) | Early Phase 1 | Recruiting | Florida Gulf Coast University | 40 | 2024-09-16 | 2024-10-04 |
| Reducing Disparities in Access to Evidence-Based Services for Attention Deficit Hyperactivity Disorder (ADHD) Through Technology Collaborative Life Skills - Control Condition, Intervention Condition | Early Phase 1 | Enrolling by invitation | San Diego State University | 350 | 2024-09-01 | 2026-04-13 |
| Cognitive Remediation for Autistic Adolescents Cognitive Remediation Therapy - Autism Spectrum Disorder | Early Phase 1 | Completed | South London and Maudsley NHS Foundation Trust | 20 | 2024-05-08 | 2025-05-25 |
| Methylphenidate and Response to Alcohol Cues Pilot Study Methylphenidate Pill - Alcohol Use Disorder, Attention Deficit Hyperactivity Disorder | Early Phase 1 | Completed | University of Florida | 31 | 2024-03-20 | 2026-02-10 |
| Virtual Reality Exercise in a Community Highschool for Children With Disabilities Virtual reality exercise - Disability Physical, Developmental Disability | Early Phase 1 | Completed | University of Alabama at Birmingham | 9 | 2023-09-18 | 2025-04-29 |
| Relapse Prevention in Stimulant Use Disorder Contrave 8Mg-90Mg Extended-Release Tablet, Bupropion - Stimulant Use, Relapse | Early Phase 1 | Withdrawn | University of California, Los Angeles | 2023-06-11 | 2023-09-22 | |
| Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy Methylphenidate, Modafinil, Placebo - Neurodevelopmental Disorders, Cerebral Palsy | Early Phase 1 | Not yet recruiting | Kuwait University | 30 | 2023-05-01 | 2023-03-08 |
| D-cycloserine Augmented Treatment for Youth With Tic Disorders d-cycloserine, Placebo pill, Behavior Therapy - Tourette Syndrome | Early Phase 1 | Withdrawn | Johns Hopkins University | 2023-04-15 | 2023-04-14 | |
| A Clinical Study Evaluating the Efficacy and Safety of Retinoic Acid in Patients With 15q11-q13 Duplication Syndrome Retinoic acid - Autism, Treatment Adherence | Early Phase 1 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 20 | 2022-04-01 | 2022-03-16 |
| S-ketamin Premedication in Pediatric EENT Surgery S-ketamine 0.3, S-ketamine 0.5, S-ketamine 2 - Emotions, Separation Anxiety | Early Phase 1 | Completed | Eye & ENT Hospital of Fudan University | 320 | 2021-03-01 | 2022-04-27 |
| Mindfulness-Based ADHD Treatment for Children: a Feasibility Study Mindfulness-Based ADHD Treatment for Children, Goal-Standard Medication (Treatment as Usual) - Attention Deficit Hyperactivity Disorder | Early Phase 1 | Completed | Yale University | 68 | 2021-02-01 | 2024-11-25 |
| Prevalence of Lidocaine Ineffectiveness in Adults With and Without ADHD Lidocaine gel - ADHD, PMS | Early Phase 1 | Completed | PhenoSolve, LLC | 90 | 2019-08-14 | 2022-10-06 |
Showing 20 of 45. Sign in to see all of them.
Attention Deficit Disorder with Hyperactivity (18) · Autism Spectrum Disorder (15) · Autistic Disorder (7) · Anxiety Disorders (3) · Developmental Disabilities (3) · Tourette Syndrome (3) · Disease (2) · Learning Disabilities (2) · Alcoholism (1) · Anxiety, Separation (1) · Ataxia (1) · Autoimmune Diseases (1) · Bipolar Disorder (1) · Cerebral Palsy (1)
Mental Disorders (45) · Attention Deficit and Disruptive Behavior Disorders (18) · Child Development Disorders, Pervasive (18) · Nervous System Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (7) · Neurologic Manifestations (6) · Pathologic Processes (6) · Behavior (5) · Brain Diseases (5) · Central Nervous System Diseases (5) · Disease Attributes (4) · Autism Spectrum Disorder (3) · Basal Ganglia Diseases (3)
Methylphenidate (4) · Methods (3) · Behavior Therapy (2) · Diet, Carbohydrate-Restricted (2) · Magnetic Resonance Imaging (2) · Amiloride (1) · Aprepitant (1) · Atomoxetine Hydrochloride (1) · Breathing Exercises (1) · Bupropion (1) · Caffeine (1) · Cognitive Behavioral Therapy (1) · Cycloserine (1) · Deep Brain Stimulation (1) · Dietary Supplements (1)
PhenoSolve, LLC (3) · Children's Hospital Medical Center, Cincinnati (2) · Spanish Foundation for Neurometrics Development (2) · University of California, Los Angeles (2) · University of Missouri-Columbia (2) · Ayelet Omer Armon (1) · Beijing Pins Medical Co., Ltd (1) · Christopher John McDougle, M.D. (1) · Eye & ENT Hospital of Fudan University (1) · Florida Gulf Coast University (1) · Johns Hopkins University (1) · Joseph Jankovic (1) · Kuwait University (1) · Massachusetts General Hospital (1) · Matthew J O'Brien, PhD, BCBA-D (1)
United States (27) · China (4) · United Kingdom (3) · France (1) · Israel (1) · Kuwait (1) · Singapore (1)
Michael Segal, MD PhD (3) · David Q Beversdorf, MD (2) · AMiya Waldman-Levi, PhD OTR/L (1) · Anwar B Almutairi, PT, PhD (1) · Byron Lai, PhD (1) · Chanaka Kahathuduwa, MBBS PhD (1) · Chris Sciammana, MD (1) · Christopher J McDougle, M.D. (1) · Daniel E Lidstone, Ph.D. (1) · David Cochran, MD, PhD (1) · Edythe D London, Ph.D. (1) · Elizabeth A Lawson, MD (1) · Ernest Pedapati, MD (1) · Esther Adi-Japha, PhD (1) · Eugene Arnold, MD (1)
PMID 11143733, PMID 18174562, PMID 18426576, PMID 23134619, PMID 24761279, PMID 24938135, PMID 25447751, PMID 29644582, PMID 31375103, PMID 38441919, PMID 39263280, PMID 9212254
K23MH113008 (1), P50MD017338 (1), R34AT009887 (1), U54MD012397 (1)