127 completed, 42 recruiting, 31 unknown, 8 enrolling by invitation. 127 Not applicable, 7 Phase 4, 6 Phase 1, 6 Phase 3, 5 Phase 2.
Follow Developmental Disabilities: new trials by email Literature Review of Developmental Disabilities trials Research Report on Developmental Disabilities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Unstuck-Early Childhood Effectiveness & Implementation Trial Unstuck and On Target for Early Childhood - Executive Function Deficits (EFD) | Not applicable | Not yet recruiting | Children's National Research Institute | 90 | 2027-08-01 | 2026-09-21 |
| ICF-Based Interdisciplinary Case Management for Individuals With Disabilities ICF-Based Interdisciplinary Case Management (Rehab-Cycle®), Conventional Care Management - Intellectual Disability, Mild to Moderate, Developmental Disability | Not applicable | Recruiting | The Hong Kong Polytechnic University | 120 | 2026-10-01 | 2026-09-10 |
| Health Engagement & Access Through Learning, Training, and Health-coaching With People With Intellectual and/or Developmental Disabilities Comprehensive Community Health, Regular Special Olympics programming - Intellectual Disabilities, Developmental Disability | Not applicable | Not yet recruiting | University of Wisconsin, Madison | 1040 | 2026-09-01 | 2026-07-29 |
| Wearable Sensor Toolkit for Infant Motor Development Motor Delay, Infant Development | Not yet recruiting | Shirley Ryan AbilityLab | 90 | 2026-09-01 | 2026-10-08 | |
| Smart Inhaler and Remote Asthma Management in Adolescents With Intellectual and Developmental Disabilities Use of active remote smart inhaler in the home setting, Use of passive remote smart inhaler in the home setting - Asthma in Children, Intellectual Disabilities (F70-F79) | Not applicable | Recruiting | Children's Hospital Los Angeles | 34 | 2026-08-10 | 2026-08-31 |
| Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities Deutetrabenazine Oral Capsule - Tardive Dyskinesia, Intellectual Disability | Phase 4 | Recruiting | University Hospitals Cleveland Medical Center | 25 | 2026-06-22 | 2026-07-06 |
| Genotype/Phenotype Correlation of MORC2 Mutations Skin biopsy, Blood sample - Charcot Marie Tooth Disease, DIFGAN | Recruiting | Hospices Civils de Lyon | 45 | 2026-06-16 | 2026-06-18 | |
| ACT Dad's Power: Feasibility RCT for Fathers of Children With Special Needs VR-based ACT, Health Talks and Simple Social Support - Developmental Disabilities | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 50 | 2026-06-01 | 2026-03-09 |
| Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Global Developmental Delay Transcranial magnetic stimulation, individualized language training - Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS) | Not applicable | Recruiting | Xiangya Hospital of Central South University | 50 | 2026-05-27 | 2026-06-02 |
| Comparing the Impact of Peer Support vs. Staff-Delivered Transportation Interventions for Young Adults With Intellectual and Developmental Disabilities. Ready to Ride - Standard Delivery, Ready to Ride - Peer Support Delivery - Intellectual Disability, Mild to Moderate, Developmental Disability | Not applicable | Enrolling by invitation | Temple University | 325 | 2026-05-21 | 2026-09-10 |
| Collaboration for Down Syndrome Progress (CDP) Down Syndrome, Chromosome Disorders | Recruiting | RTI International | 1400 | 2026-05-01 | 2026-06-04 | |
| ACT Dad Interview: ACT for Fathers of Children With Special Needs Semi-structured Focus Group Interview - Caregiver Mental Health, Parenting Stress | Not yet recruiting | The Hong Kong Polytechnic University | 20 | 2026-05-01 | 2026-05-18 | |
| Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD) | Recruiting | Healing Hope International | 100 | 2026-03-01 | 2026-03-25 | |
| Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action - Developmental Delays | Not applicable | Recruiting | Northwestern University | 1269 | 2026-02-16 | 2026-10-21 |
| A Self-Instructional Online Program for Early Childhood and Elementary Teachers Supporting Autistic Children and Children With Developmental Delays SEED Online Self-Instructional Program, Comparison Educational Materials (Kit for Kids) - Autism Spectrum Disorder, Developmental Disabilities | Not applicable | Recruiting | Boin Choi | 70 | 2026-02-05 | 2026-04-13 |
| DENTOFACIAL-PBT Stage 2 - Feasibility Study Orthopantomogram (or a set of Lateral Oblique Radiographs) - Head and Neck Cancer, Radiotherapy Side Effect | Enrolling by invitation | Manchester University NHS Foundation Trust | 255 | 2026-01-16 | 2026-01-26 | |
| Online Learning Module to Advance Research Related to People With Disabilities eLearning module, Control - Developmental Disability, Intellectual Disability | Not applicable | Completed | Albert Einstein College of Medicine | 108 | 2025-12-16 | 2026-07-14 |
| Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) No Intervention: Observational Cohort - Baker Gordon Syndrome, Rare Neurodevelopmental Conditions | Recruiting | University of Missouri-Columbia | 100 | 2025-12-04 | 2026-01-09 | |
| Effects of CIMT With and Without Robotic Gloves in Children With Hemiplegic CP CIMT with robotic glove, CIMT with standard rehabilitation - Child Development Disorder | Not applicable | Recruiting | Riphah International University | 34 | 2025-10-29 | 2025-11-25 |
| Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy Therapist Training on Powered Mobility Implementation, Powered Mobility Intervention for Child-Caregiver Dyads - Cerebral Palsy Children, Motor Disabilities | Not applicable | Recruiting | Oregon Health and Science University | 70 | 2025-10-01 | 2026-07-06 |
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Intellectual Disability (51) · Autism Spectrum Disorder (42) · Autistic Disorder (26) · Learning Disabilities (22) · Cerebral Palsy (19) · Down Syndrome (10) · Epilepsy (9) · Mental Disorders (9) · Neurodevelopmental Disorders (9) · Premature Birth (9) · Language Development Disorders (8) · Attention Deficit Disorder with Hyperactivity (7) · Depression (7) · Child Behavior (6)
Mental Disorders (219) · Neurodevelopmental Disorders (219) · Nervous System Diseases (108) · Pathological Conditions, Signs and Symptoms (95) · Neurologic Manifestations (93) · Signs and Symptoms (89) · Neurobehavioral Manifestations (87) · Child Development Disorders, Pervasive (57) · Behavior (45) · Central Nervous System Diseases (33) · Communication Disorders (29) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (28) · Brain Diseases (27) · Brain Damage, Chronic (19) · Behavioral Symptoms (18)
Therapeutics (6) · Methods (3) · Blood Specimen Collection (2) · Focus Groups (2) · Methylphenidate (2) · Neuropsychological Tests (2) · Risperidone (2) · (tris(diphenylphosphinomethyl)phenylborate)(p-tolylnitrido)iron(I) (1) · Animal Assisted Therapy (1) · Atomoxetine Hydrochloride (1) · BPN14770 (1) · Body Composition (1) · Botulinum Toxins, Type A (1) · COVID-19 Testing (1) · Capsules (1)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (5) · Stanford University (5) · Chang Gung Memorial Hospital (4) · The Hong Kong Polytechnic University (4) · University of Illinois at Chicago (4) · University of Wisconsin, Madison (4) · Hacettepe University (3) · Icahn School of Medicine at Mount Sinai (3) · Riphah International University (3) · Virginia Commonwealth University (3) · Boston Medical Center (2) · Boston University (2) · Centre for Addiction and Mental Health (2) · Chang Gung University (2) · Children's Hospital Los Angeles (2)
United States (105) · Canada (13) · France (12) · Taiwan (10) · Turkey (Türkiye) (8) · Spain (6) · Israel (5) · Pakistan (5) · United Kingdom (5) · China (4) · Italy (4) · Norway (4) · Germany (3) · Netherlands (3) · South Korea (3)
Alexander Kolevzon, MD (3) · Anne Wheeler, PhD (2) · Beth Pfeiffer, PhD, OTR/L, BCP, FAOTA (2) · Jessica Kramer, PhD, OTR/L (2) · Larry Yin, MD, MSPH (2) · Lin-Ju Kang, PhD (2) · Mary A Khetani, ScD (2) · Paige Siper, Ph.D. (2) · Stephen Ruedrich, MD (2) · AMiya Waldman-Levi, PhD OTR/L (1) · Aaron Besterman, MD, MD (1) · Aftab Ansar Lodhi, MS-PT (1) · Ahmet Emir, Msc (1) · Alan Ettinger, MD (1) · Alexander A Ostanin, MD, PhD (1)
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1UM1TR004400 (1), 2025 (1), P01HD026927 (1), P20GM103436 (1), P50HD103525 (1), P50MD017338 (1), R01DC007660 (1), R01HD039017 (1), R01HD059205 (1), R01HD079642 (1), R01HD117997 (1), R01MH104355 (1), R01MH144622 (1), R03HD086330 (1), R21DC015225 (1)