14 completed, 4 withdrawn, 1 recruiting. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 14, Withdrawn 4, Recruiting 1 |
Follow Nematode Infections: new trials by email Literature Review of Nematode Infections trials Research Report on Nematode Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases Moxidectin, Ivermectin - Onchocerciasis, Ascaris Lumbricoides Infection | Phase 4 | Recruiting | Kirby Institute | 52000 | 2025-08-04 | 2025-11-21 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Loiasis Cross-reactive Antigenemia and Treatment-related Adverse Events Ivermectin - Loiasis | Phase 4 | Completed | Washington University School of Medicine | 41 | 2021-07-30 | 2022-09-29 |
| Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy Ivermectin - Ivermectin, Onchocerciasis | Phase 4 | Completed | Robert Colebunders | 91 | 2017-10-01 | 2019-01-07 |
| Triple Combinations Against Hookworm Infections in Lao Albendazole, Pyrantel Pamoate, Oxantel Pamoate - Hookworm Infection | Phase 4 | Completed | Swiss Tropical & Public Health Institute | 420 | 2017-09-27 | 2018-05-08 |
| Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana Mebendazole - Hookworm Infections | Phase 4 | Withdrawn | PATH | 2017-09-01 | 2017-11-17 | |
| Efficacy and Safety of a Multi-dose Regimen of Mebendazole Against Hookworm in Children Treatment with one of the two regimens of mebendazole - Hookworm | Phase 4 | Completed | Jennifer Keiser | 186 | 2017-07-25 | 2019-06-17 |
| Twice Yearly Treatment for the Control of LF 400 μg/kg Ivermectin + 400 mg Albendazole - Lymphatic Filariasis, Helminth Infection | Phase 4 | Completed | Noguchi Memorial Institute for Medical Research | 1462 | 2017-05-19 | 2020-02-26 |
| Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis Praziquantel - Schistosomiasis | Phase 4 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-04-06 | 2019-12-17 | |
| The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children Albendazole, Placebo - Intestinal Helminthiasis, Diarrhea | Phase 4 | Withdrawn | Oxford University Clinical Research Unit, Vietnam | 2016-02-01 | 2016-12-15 | |
| Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya albendazole - Helminthiasis, Nematode Infection | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 21761 | 2015-03-01 | 2018-08-31 |
| Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis azithromycin, ivermectin, albendazole - Trachoma, Lymphatic Filariasis | Phase 4 | Withdrawn | Emory University | 2014-02-01 | 2014-05-22 | |
| Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis Diethylcarbamazine, Ivermectin - Loiasis | Phase 4 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 155 | 2012-04-01 | 2016-11-09 |
| Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2 Mebendazole - Ascaris Lumbricoides, Ascaris Suum | Phase 4 | Completed | University Ghent | 250 | 2011-12-01 | 2014-12-05 |
| The Efficacy of Five Anthelmintic Regimes Against Trichuris Trichiura Infections in Schoolchildren in Jimma, Ethiopia Albendazole, 2 x 400mg, Albendazole 400mg, Mebendazole 500mg - Infection by Trichuris Trichiura | Phase 4 | Completed | University Ghent | 2250 | 2010-12-01 | 2011-04-01 |
| Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora albendazole - Intestinal Diseases, Helminthiasis | Phase 4 | Completed | Albert Schweitzer Hospital | 200 | 2010-08-01 | 2013-01-24 |
| Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection Diethylcarbamazine, Albendazole, Doxycycline - Filarial; Infestation | Phase 4 | Completed | Indian Council of Medical Research | 146 | 2009-02-01 | 2013-12-09 |
| Efficacy Albendazole and Levamisole Against STH on Unguja Albendazole, Levamisole - Ascariasis, Trichuriasis | Phase 4 | Completed | Natural History Museum, United Kingdom | 20 | 2006-06-01 | 2008-04-17 |
| Impact of Albendazole -Ivermectin on Wuchereria Bancrofti in Mali ''albendazole'' and ''ivermectin'' - Lymphatic Filariasis | Phase 4 | Completed | Centre d'Appui à la lutte contre la Maladie | 1139 | 2001-05-01 | 2016-05-27 |
Elephantiasis, Filarial (5) · Trichuriasis (5) · Hookworm Infections (4) · Ancylostomiasis (3) · Coinfection (2) · Helminthiasis (2) · Loiasis (2) · Onchocerciasis (2) · Trachoma (2) · Ascariasis (1) · Communicable Diseases (1) · Diarrhea (1) · Epilepsy (1) · Filariasis (1) · Intestinal Diseases (1)
Infections (19) · Parasitic Diseases (18) · Helminthiasis (17) · Secernentea Infections (16) · Spirurida Infections (10) · Filariasis (9) · Strongylida Infections (6) · Vector Borne Diseases (6) · Adenophorea Infections (5) · Enoplida Infections (5) · Hemic and Lymphatic Diseases (5) · Lymphatic Diseases (5) · Lymphedema (5) · Mosquito-Borne Diseases (5)
Albendazole (10) · Ivermectin (7) · Mebendazole (4) · Diethylcarbamazine (2) · Albumins (1) · Azithromycin (1) · Doxycycline (1) · Levamisole (1) · Praziquantel (1) · Pyrantel Pamoate (1) · Therapeutics (1) · moxidectin (1) · oxantel pamoate (1)
London School of Hygiene and Tropical Medicine (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · University Ghent (2) · Albert Schweitzer Hospital (1) · Centre d'Appui à la lutte contre la Maladie (1) · Emory University (1) · Indian Council of Medical Research (1) · Jennifer Keiser (1) · Kirby Institute (1) · Natural History Museum, United Kingdom (1) · Noguchi Memorial Institute for Medical Research (1) · Oxford University Clinical Research Unit, Vietnam (1) · PATH (1) · Robert Colebunders (1) · Swiss Tropical & Public Health Institute (1)
Cameroon (3) · Ethiopia (3) · Tanzania (3) · Ghana (2) · Vietnam (2) · Angola (1) · Argentina (1) · Australia (1) · Brazil (1) · Cambodia (1) · Democratic Republic of the Congo (1) · Gabon (1) · India (1) · Kenya (1) · Laos (1)
Amy D Klion, M.D. (2) · Andrea Graham, PhD (1) · Dziedzom K de Souza, PhD (1) · Huub C Gelderblom, MD, PhD, MPH (1) · Jacqueline Leung, MA (1) · Jennifer Keiser, PhD (1) · Jozef Vercruysse, PhD (1) · Lourduraj J De Britto, M.D (1) · Michael Cappello, MD (1) · Michael Wilson, PhD (1) · Michel Mandro, MD (1) · Nghia Ho Dang Trung, PhD, MD (1) · Rachel L Pullan, PhD (1) · Ricardo Thompson, PhD (1) · Stephen Baker, PhD (1)
PMID 18775092, PMID 22189084, PMID 23981378, PMID 24550339, PMID 25299391, PMID 26482774, PMID 26691247, PMID 27266697, PMID 28329346, PMID 28855148, PMID 28969715, PMID 29673735, PMID 31006575, PMID 31193620, PMID 31314757, PMID 31398204, PMID 31923177, PMID 37152362