19 completed, 4 withdrawn, 3 recruiting, 1 active not recruiting. 8 Phase 3, 7 Phase 4, 6 Not applicable, 5 Phase 1, 5 Phase 2.
Follow Mebendazole: new trials by email Literature Review of Mebendazole trials Research Report on Mebendazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg - Onchocerciasis (River Blindness), Schistosomiasis | Not applicable | Recruiting | Uwemedimo Friday Ekpo | 5760 | 2026-07-01 | 2026-07-16 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura Oxantel Pamoate, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 2 | Completed | Jennifer Keiser | 163 | 2025-04-16 | 2025-06-08 |
| Possible Efficacy and Safety of Mebendazole in Patients With Ulcerative Colitis Treated With Mesalamine Mebendazole - Ulcerative Colitis | Not applicable | Recruiting | Tanta University | 46 | 2024-04-20 | 2026-02-06 |
| Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer Metabolic treatment - Cancer, Overall Survival | Phase 3 | Withdrawn | Health Clinics Limited | 2022-05-23 | 2022-07-18 | |
| Nutrition Intervention to Address Anemia Among Adolescent Girls in Liberia Iron and folic acid (IFA) supplementation, Targeted nutrition education, Mebendazole Pill - Nutritional Anemia, Nutritional Deficiency | Not applicable | Withdrawn | Boston Children's Hospital | 2021-10-01 | 2021-11-22 | |
| To Study the Effects of Addition of Mebendazole to Lenvatinib in Cirrhotics With Advanced Hepatocellular Carcinoma. Lenvatinib, Mebendazole, Placebo - Hepatocellular Carcinoma, Liver Cirrhosis | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 170 | 2020-07-10 | 2021-10-05 |
| RDD1609 as a Treatment for Idiopathic Pruritus Ani RDD1609, Mebendazole 100 MG - Idiopathic Pruritus Ani | Phase 2 | Withdrawn | RDD Pharma Ltd | 2020-05-01 | 2022-11-03 | |
| Human Soil Transmitted Helminths (STH) Resistance to Benzimidazole in School Aged Children Living in Gabon Benzimidazole Anthelmintic - Helminths Infection, Drug Resistance | Phase 4 | Completed | Centre de Recherche Médicale de Lambaréné | 255 | 2019-11-11 | 2021-08-02 |
| Efficacy and Safety of a New Chewable Versus the Swallowable Tablet of Mebendazole Against Hookworm Mebendazole - Hookworm Infections | Phase 2 | Completed | Swiss Tropical & Public Health Institute | 397 | 2019-07-12 | 2020-07-20 |
| Monitoring Drug Efficacy and Anthelmintic Resistance in Soil-transmitted Helminth Programs Benzimidazoles - Soil-transmitted Helminth Infections | Completed | University Ghent | 9457 | 2019-05-15 | 2023-08-29 | |
| Mebendazole as Adjuvant Treatment for Colon Cancer Folfox with avastin, Mebendazole - Colorectal Cancer | Phase 3 | Recruiting | Sherief Abd-Elsalam | 40 | 2019-04-01 | 2019-04-24 |
| A Clinical Safety and Efficacy Study of Mebendazole on GI Cancer or Cancer of Unknown Origin. ReposMBZ - Cancer of the Gastrointestinal Tract, Cancer of Unknown Origin | Phase 1 / Phase 2 | Terminated | Repos Pharma | 11 | 2018-05-25 | 2020-01-22 |
| Triple Combinations Against Hookworm Infections in Lao Albendazole, Pyrantel Pamoate, Oxantel Pamoate - Hookworm Infection | Phase 4 | Completed | Swiss Tropical & Public Health Institute | 420 | 2017-09-27 | 2018-05-08 |
| Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana Mebendazole - Hookworm Infections | Phase 4 | Withdrawn | PATH | 2017-09-01 | 2017-11-17 | |
| Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors Mebendazole - Medulloblastoma, Astrocytoma, Grade III | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 16 | 2016-05-01 | 2022-06-23 |
| A Study to Assess the Efficacy and Safety of Mebendazole for the Treatment of Helminth Infections in Pediatric Participants Mebendazole, Placebo - Helminth Infections | Phase 3 | Completed | Janssen Research & Development, LLC | 295 | 2014-12-01 | 2016-11-04 |
| A Study to Assess the Effect of Food on the Bioavailability of Mebendazole From a Fast-Disintegrating Chewable Formulation of Mebendazole in Healthy Participants Mebendazole - fasted state (Treatment A), Mebendazole - fed state (Treatment B) - Healthy | Phase 1 | Completed | Janssen Research & Development, LLC | 1 | 2014-02-01 | 2014-06-27 |
| A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Mebendazole, Vincristine, Carboplatin - Pilomyxoid Astrocytoma, Pilocytic Astrocytoma | Phase 1 / Phase 2 | Active not recruiting | Julie Krystal | 10 | 2013-10-22 | 2026-08-06 |
Showing 20 of 30. Sign in to see all of them.
Hookworm Infections (6) · Ancylostomiasis (5) · Trichuriasis (5) · Glioblastoma (3) · Infections (3) · Parasitic Diseases (3) · Anemia (2) · Astrocytoma (2) · Diffuse Intrinsic Pontine Glioma (2) · Enterobiasis (2) · Glioma (2) · Malnutrition (2) · Trematode Infections (2) · Amebiasis (1) · Behavior (1)
Swiss Tropical & Public Health Institute (4) · University Ghent (3) · DBL -Institute for Health Research and Development (2) · Janssen Research & Development, LLC (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · Boston Children's Hospital (1) · Centre de Recherche Médicale de Lambaréné (1) · Cornell University (1) · Health Clinics Limited (1) · Institute of Liver and Biliary Sciences, India (1) · Janssen-Cilag Ltd. (1) · Jennifer Keiser (1) · Johns Hopkins Bloomberg School of Public Health (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Julie Krystal (1)
Tanzania (6) · Ethiopia (3) · United States (3) · Cambodia (2) · Egypt (2) · Ghana (2) · Laos (2) · Rwanda (2) · Uganda (2) · United Kingdom (2) · Vietnam (2) · Argentina (1) · Australia (1) · Bangladesh (1) · Belgium (1)
Jennifer Keiser, PhD (2) · Jennifer Keiser, Professor (2) · Bruno Levecke, PhD (1) · Fatma Zakaria, Prof (1) · Gary Gallia, MD (1) · Hammed Mogaji, PhD (1) · James M Tielsch, PhD (1) · Jeanette Melrose, MD (1) · Jozef Vercruysse, PhD (1) · Julia Rubin-Smith, MD, MSPH (1)
PMID 19176737, PMID 19535425, PMID 21885077, PMID 22189084, PMID 25299391, PMID 26426270, PMID 29673735, PMID 33150325, PMID 35385794, PMID 38563751, PMID 41364144, PMID 42486129