Lymphedema: Clinical Trials

598 trials for Lymphedema, newest first

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314 completed, 93 unknown, 82 recruiting, 34 terminated. 341 Not applicable, 42 Phase 2, 20 Phase 3, 17 Phase 1, 16 Phase 4.

By phase and status

PhaseTrialsStatus
Not applicable341Completed 161, Unknown 61, Recruiting 45, Not yet recruiting 22, Active not recruiting 19, Terminated 18, Withdrawn 9, Enrolling by invitation 5, Suspended 1
Phase 242Completed 24, Unknown 6, Recruiting 5, Terminated 5, Enrolling by invitation 1, Suspended 1
Phase 320Completed 12, Active not recruiting 2, Recruiting 2, Unknown 2, Enrolling by invitation 1, Terminated 1
Phase 117Completed 8, Unknown 5, Terminated 4
Phase 416Completed 12, Recruiting 2, Withdrawn 2
Early Phase 14Recruiting 2, Completed 1, Terminated 1

Follow Lymphedema: new trials by email Literature Review of Lymphedema trials Research Report on Lymphedema

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Early Intervention
Juzo Compression Sleeve and Glove, Compression Sleeve Sensor - Breast Cancer, Breast Cancer Treatment Related Lymphedema
Not applicableNot yet recruitingMassachusetts General Hospital402027-05-012026-07-13
Preventing Lymphedema in Patients Undergoing Surgical Treatment for Head and Neck Cancer Through Vein Reconstruction
Facial Vein Reconstruction - Head and Neck Cancer
Not applicableRecruitingUniversity of Pittsburgh372026-10-032026-10-06
Evaluation of Novel Iron-based Lymphatic Mapping Agent, Magtrace, for Delayed Sentinel Lymph Node Biopsy (SLNB) in Ductal Carcinoma In-Situ (DCIS)
Magtrace - Ductal Carcinoma in Situ
Phase 2SuspendedUniversity of Florida302026-10-012026-09-11
Use of Reconstructive Microsurgery for the Treatment of Lymphedema
Surgery with and without the aid of Indocyanine Green (ICG) - Lymphedema
RecruitingIstituto Ortopedico Rizzoli152026-09-292026-10-22
Better Options for Lymphatic Filariasis Treatment
MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole - Lymphatic Filariasis, Scabies
Phase 3RecruitingMedicines Development for Global Health51002026-09-282026-10-07
Evaluation of Adherence to Rehabilitation: Autonomous and Guided, in the Observation and Treatment Response of Head and Neck Lymphedema in Neoplasms During Radiotherapy
Autonomous Guided Rehabilitation Program, Usual recommended care - Lymphedema, Head and Neck Neoplasms
Not applicableNot yet recruitingHopital Forcilles562026-09-222026-09-24
Prediction Of Lymphedema In Patients With Inflammatory BreastCancer Using Preoperative Bioimpedance Measurements
Neoadjuvant therapy - Lymphedema, Inflammatory Breast Cancer (IBC)
RecruitingM.D. Anderson Cancer Center1502026-09-162026-10-02
Effectiveness of a Tele-Rehabilitation-Based Exercise and Self-Lymphatic Drainage Program Supported by Self-Management for Breast Cancer-Related Lymphedema
Tele-rehabilitation-Based Exercise and Self-Lymphatic Drainage Program, Home-Based Exercise and Self-Lymphatic Drainage Program - Breast Cancer-Related Lymphedema, Lymphedema
Not applicableActive not recruitingIstanbul University642026-09-072026-09-09
Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema
Extracorporeal Shock Wave Therapy (ESWT), Sham Extracorporeal Shock Wave Therapy (Sham ESWT) - Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy
Not applicableRecruitingGazi University362026-09-012026-09-15
Biological Profile of Primary and Secondary Lymphedema: Inflammatory, Endothelial, Metabolic, Lymphatic, and Fibrotic Markers
Primary Lymphedema, Secondary Lymphedema
Not yet recruitingUniversity Medical Centre Ljubljana902026-09-012026-08-20
Inelastic Compression Use in Primary Lymphedema
Compression device with medium pressure (23-32 mmHg) - Lymphedema Primary
Not applicableNot yet recruitingUniversity School of Physical Education, Krakow, Poland302026-09-012026-10-08
Effects of Core-Focused Exercise Training and Kinesiology Taping in Women With Breast Cancer-Related Lymphedema
Complex Decongestive Therapy, Trunk Focused exercises, Kinesiology taping - Breast Cancer Related Lymphedema
Not applicableNot yet recruitingHacettepe University462026-08-152026-06-29
Evaluate Advanced Pneumatic Compression Device With Revised Compression Programming for Lymphedema Treatment
Advanced pneumatic compression device (APCD), Advanced pneumatic compression device (APCD) with revised compression programming, Indocyanine Green (IC-Green) - Lower Extremity Lymphedema
Early Phase 1RecruitingTactile Medical52026-07-092026-08-11
Advancing Patient Care for Lymphatic Pain and Lymphedema
The-Optimal-Lymph-Flow - Breast Cancer, Pain
Not applicableNot yet recruitingUniversity of Missouri, Kansas City352026-07-012026-07-14
Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations
Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg - Onchocerciasis (River Blindness), Schistosomiasis
Not applicableRecruitingUwemedimo Friday Ekpo57602026-07-012026-07-16
Clinical Lymphedema Evaluation - Advancing Reconstruction of Head and Neck Lymphatics With Symani
Symani Surgical System - Lymphedema, Lymphedema of Face
Not applicableRecruitingMMI (Medical Microinstruments, Inc.)302026-06-192026-07-13
Boosted Compression for Lower Limb Chronic Edema
Conservative edema treatment (complex decongestive therapy), Conservative edema treatment with boosted compression therapy - Chronic Edema, Lymphedema
Not applicableRecruitingUniversiteit Antwerpen1602026-06-012026-07-16
Preoperative Indocyanine Green Lymphography and High-Frequency Ultrasound as Predictors of Lymphaticovenous Anastomosis Outcome in Post-Mastectomy Upper Limb Lymphedema
lymphatic-venous anastamosis - Lymphedema Arm, Breast Cancer Lymphedema
Not applicableNot yet recruitingAssiut University302026-05-272026-05-29
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
Paravertebral block, Erector Spinae block - Mastectomy; Lymphedema, Chronic Pain
Not applicableRecruitingAmerican University of Beirut Medical Center1322026-05-192026-06-02
The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)
Resistance exercise - Lymphedema
Not applicableRecruitingCarsten Bogh Juhl362026-05-052026-09-18

Showing 20 of 598. Sign in to see all of them.

Narrower conditions

Breast Neoplasms (191)  ·  Breast Cancer Lymphedema (123)  ·  Elephantiasis, Filarial (41)  ·  Head and Neck Neoplasms (22)  ·  Motor Activity (20)  ·  Edema (18)  ·  Neoplasm Metastasis (16)  ·  Pain (15)  ·  Fibrosis (14)  ·  Neoplasms (13)  ·  Postoperative Complications (8)  ·  Filariasis (7)  ·  Onchocerciasis (7)  ·  Vulvar Neoplasms (7)

Broader conditions

Hemic and Lymphatic Diseases (598)  ·  Lymphatic Diseases (594)  ·  Neoplasms (247)  ·  Neoplasms by Site (236)  ·  Skin and Connective Tissue Diseases (222)  ·  Pathological Conditions, Signs and Symptoms (216)  ·  Skin Diseases (214)  ·  Breast Diseases (191)  ·  Pathologic Processes (177)  ·  Postoperative Complications (127)  ·  Signs and Symptoms (55)  ·  Infections (46)  ·  Helminthiasis (42)  ·  Nematode Infections (42)

Interventions

Albendazole (20)  ·  Ivermectin (18)  ·  Manual Lymphatic Drainage (17)  ·  Exercise (16)  ·  Indocyanine Green (10)  ·  Diethylcarbamazine (9)  ·  carbohydrate-deficient transferrin (7)  ·  Low-Level Light Therapy (6)  ·  Surveys and Questionnaires (6)  ·  Acupuncture Therapy (5)  ·  Exercise Therapy (5)  ·  Physical Therapy Modalities (5)  ·  Resistance Training (5)  ·  Azithromycin (4)  ·  Compression Bandages (4)

Sponsors

Cairo University (13)  ·  Chang Gung Memorial Hospital (11)  ·  Stanford University (10)  ·  Tactile Medical (10)  ·  Memorial Sloan Kettering Cancer Center (9)  ·  Odense University Hospital (9)  ·  Vanderbilt University (9)  ·  Washington University School of Medicine (9)  ·  M.D. Anderson Cancer Center (8)  ·  Universitaire Ziekenhuizen KU Leuven (8)  ·  Koya Medical, Inc. (7)  ·  Marmara University (7)  ·  Massachusetts General Hospital (7)  ·  Copenhagen University Hospital, Rigshospitalet (6)  ·  University Hospital, Montpellier (6)

Countries

United States (167)  ·  Turkey (Türkiye) (74)  ·  Denmark (27)  ·  France (24)  ·  Spain (24)  ·  China (23)  ·  Egypt (22)  ·  Taiwan (21)  ·  Belgium (20)  ·  Canada (17)  ·  South Korea (14)  ·  United Kingdom (14)  ·  Netherlands (12)  ·  Australia (11)  ·  Brazil (10)

Top investigators

Stanley G Rockson (5)  ·  Stanley G Rockson, MD (4)  ·  Eric Ottesen, MD (3)  ·  Gary J Weil, MD (3)  ·  Gary Weil, MD (3)  ·  Violeta Pajero Otero, MRes (3)  ·  Alphonse G Taghian, MD PhD (2)  ·  Alphonse G Taghian, MD, PhD (2)  ·  Anke Bergmann, PhD (2)  ·  Anne Saarikko, MD, PhD (2)  ·  Banu Dilek (2)  ·  Caroline Lilja, MD (2)  ·  Esra Giray, MD (2)  ·  Eunjoo Yang, PhD (2)

Results publications

PMID 11873261, PMID 22610930, PMID 32228663, PMID 42848323, PMID 10656038, PMID 17684090, PMID 21558848, PMID 23540561, PMID 30333315, PMID 30570358, PMID 35533701, PMID 37262040, PMID 37608354, PMID 10201543, PMID 10971418, PMID 10993089, PMID 11307660, PMID 11332311, PMID 12657232, PMID 12861145, PMID 15542159, PMID 16184458, PMID 16445334, PMID 17040628, PMID 17539462, PMID 18089142, PMID 18323550, PMID 18365531, PMID 18428212, PMID 18482765, PMID 18691823, PMID 18809192, PMID 19001331, PMID 19020699, PMID 19031114, PMID 19081121, PMID 19273407, PMID 19534633, PMID 19675330, PMID 19771507, PMID 19892098, PMID 20027220, PMID 20163847, PMID 20556760, PMID 20665892, PMID 20808486, PMID 20850849, PMID 21148134, PMID 21190493, PMID 21240649

NIH funding

P30CA068485 (4), U10CA101165 (4), R01CA139118 (3), 2018 (2), 2023 (2), P30CA033572 (2), UG1CA189867 (2), 2017 (1), 2019 (1), 2025 (1), K12CA088084 (1), P30CA013330 (1), P30CA015083 (1), P30CA043703 (1), P30CA124435 (1)