8 completed, 2 not yet recruiting, 2 unknown. 5 Phase 3, 4 Not applicable, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Not yet recruiting 2 |
| Not applicable | 4 | Completed 2, Unknown 2 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow Ascariasis: new trials by email Literature Review of Ascariasis trials Research Report on Ascariasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras Placebo, Albendazole 400 mg, Albendazole Plus Ivermectin - Trichuriasis, Strongyloidiasis | Phase 3 | Not yet recruiting | Mundo Sano Foundation | 368 | 2026-11-01 | 2026-06-23 |
| Follow-up Assessment of Change in Soil-transmitted Helminths Infection Intensity in Uganda Albendazole 400mg, Ivermectin 3 mg - Ascariasis | Phase 3 | Not yet recruiting | Jennifer Keiser | 450 | 2026-10-01 | 2026-10-14 |
| Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC Ivermectin 1.5 mg ODT, Ivermectin 3 mg Oral Tablet, Albendazole 400 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 2 | Completed | Jennifer Keiser | 260 | 2024-06-05 | 2025-09-22 |
| Efficacy and Safety of Moxidectin-Albendazole Co-administration in SAC Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Placebo Moxidectin - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 224 | 2024-05-14 | 2025-09-19 |
| Efficacy and Safety of MOX/ALB Co-administration Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Ivermectin 3 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 255 | 2021-06-15 | 2024-01-24 |
| Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL] - Trichuriasis, Ascariasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 536 | 2021-03-01 | 2024-12-05 |
| Soil-transmitted Helminth Reinfection Rates After Single and Repeated School Hygiene Education Health hygiene education - Helminthiasis, Ascaris Infection | Not applicable | Unknown | Universitas Sumatera Utara | 432 | 2019-03-04 | 2020-01-14 |
| Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in Poland Tests for diagnosis of intestinal parasitic diseases - Intestinal Disease, Parasitic, Chronic Disease | Completed | Nicolaus Copernicus University | 22 | 2018-02-17 | 2020-03-26 | |
| Impact of A. Lumbricoides on Pulmonary Aspergillosis Development Interleukin-1B, Interleukin-4, Interleukin-6 - COPD Exacerbation Acute, Ascaris Lumbricoides Infection | Not applicable | Unknown | Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan | 200 | 2015-05-01 | 2023-08-01 |
| Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children Albendazole, Vitamin C - Intestinal Helminthiasis, Ascariasis | Not applicable | Completed | London School of Hygiene and Tropical Medicine | 2377 | 2013-01-01 | 2015-04-10 |
| Efficacy Albendazole and Levamisole Against STH on Unguja Albendazole, Levamisole - Ascariasis, Trichuriasis | Phase 4 | Completed | Natural History Museum, United Kingdom | 20 | 2006-06-01 | 2008-04-17 |
| Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections albendazole vs. combined albendazole/ivermectin treatment - Ascariasis, Trichuriasis | Not applicable | Completed | Centers for Disease Control and Prevention | 550 | 2005-02-01 | 2005-11-17 |
Trichuriasis (8) · Hookworm Infections (7) · Ancylostomiasis (6) · Helminthiasis (2) · Intestinal Diseases, Parasitic (2) · Strongyloidiasis (2) · Aspergillosis (1) · Chronic Disease (1) · Cryptosporidiosis (1) · Echinococcosis (1) · Giardiasis (1) · Intestinal helminthiasis (1) · Lice Infestations (1) · Malaria (1)
Ascaridida Infections (12) · Infections (12) · Nematode Infections (12) · Parasitic Diseases (12) · Secernentea Infections (12) · Helminthiasis (10) · Adenophorea Infections (9) · Enoplida Infections (9) · Strongylida Infections (8) · Digestive System Diseases (2) · Disease Attributes (2) · Gastrointestinal Diseases (2) · Intestinal Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2)
Albendazole (8) · Ivermectin (5) · Tablets (4) · moxidectin (3) · Ascorbic Acid (1) · Interferon-gamma Release Tests (1) · Levamisole (1)
Jennifer Keiser (5) · Centers for Disease Control and Prevention (1) · London School of Hygiene and Tropical Medicine (1) · Mundo Sano Foundation (1) · Natural History Museum, United Kingdom (1) · Nicolaus Copernicus University (1) · Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan (1) · Universitas Sumatera Utara (1)
Tanzania (4) · Côte d’Ivoire (1) · Guatemala (1) · Honduras (1) · Indonesia (1) · Kenya (1) · Poland (1) · Uganda (1) · Uzbekistan (1)
Alejandro Javier Krolewiecki, PhD, MD (1) · Byron Arana, MD (1) · Gabriela Matamoros, PhD, MSc, BSc (1) · Jennifer Keiser, Prof. (1) · Michael J Beach, Ph.D. (1) · Rizky KA Nasution, MD (1) · Simon J Brooker, DPhil (1)
PMID 18775092, PMID 26170395, PMID 34632308, PMID 36354034, PMID 37357904, PMID 40675166, PMID 40975108