19 completed, 4 not yet recruiting, 4 recruiting, 1 active not recruiting. 11 Phase 2, 8 Phase 3, 5 Not applicable, 5 Phase 4, 2 Phase 1.
Follow Trichuriasis: new trials by email Literature Review of Trichuriasis trials Research Report on Trichuriasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita Emodepside, Albendazole 400 mg - Trichuris Infection | Phase 2 | Not yet recruiting | Jennifer Keiser | 100 | 2026-11-15 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras Placebo, Albendazole 400 mg, Albendazole Plus Ivermectin - Trichuriasis, Strongyloidiasis | Phase 3 | Not yet recruiting | Mundo Sano Foundation | 368 | 2026-11-01 | 2026-06-23 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Controlled Human Infection Study of Orally Administered Trichuris Trichiura Eggs in Naïve Adults Trichuris trichiura Egg Inoculum - Whipworm, Trichuriasis | Phase 1 | Recruiting | George Washington University | 18 | 2025-09-10 | 2026-06-04 |
| Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases Moxidectin, Ivermectin - Onchocerciasis, Ascaris Lumbricoides Infection | Phase 4 | Recruiting | Kirby Institute | 52000 | 2025-08-04 | 2025-11-21 |
| Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura Oxantel Pamoate, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 2 | Completed | Jennifer Keiser | 163 | 2025-04-16 | 2025-06-08 |
| Safety, Tolerability and PK of Single and Multiple Doses of Oxantel Pamoate Tablets Oxantel Pamoate, Placebo - Healthy | Phase 1 | Completed | Swiss Tropical & Public Health Institute | 45 | 2025-01-27 | 2025-08-28 |
| A Safety and Efficacy Study of Different Doses of Oxfendazole Compared to a Single Dose of Albendazole to Treat Trichuris Trichiura Infection in Adults Albendazole, Oxfendazole - Trichuriasis | Phase 2 | Recruiting | Asociacion Benefica Prisma | 249 | 2024-09-07 | 2026-07-28 |
| Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults Oxfendazole, Albendazole - Trichuris Infection | Phase 2 | Not yet recruiting | Oxfendazole Development Group | 250 | 2024-07-01 | 2023-11-08 |
| Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC Ivermectin 1.5 mg ODT, Ivermectin 3 mg Oral Tablet, Albendazole 400 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 2 | Completed | Jennifer Keiser | 260 | 2024-06-05 | 2025-09-22 |
| Efficacy and Safety of Moxidectin-Albendazole Co-administration in SAC Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Placebo Moxidectin - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 224 | 2024-05-14 | 2025-09-19 |
| Efficacy of Ivermectin-albendazole vs Albendazole Alone in School-aged Children Infected With Trichuris Trichiura IVM (200 µg/kg) + ALB (400 mg), ALB (400mg) - Trichuriasis | Phase 3 | Completed | Jennifer Keiser | 161 | 2023-10-09 | 2024-04-10 |
| Cement flooRs AnD chiLd hEalth (CRADLE) Concrete household floor - Ascaris Lumbricoides Infection, Necator Americanus Infection | Not applicable | Active not recruiting | Stanford University | 800 | 2023-09-24 | 2026-04-28 |
| Evaluating Impact of Improved Floors on Health Sealed washable floor plus behaviour change, Behaviour change intervention, Routine deworming - Diarrhoeal Disease, Hookworm Infection | Not applicable | Completed | London School of Hygiene and Tropical Medicine | 2200 | 2023-04-12 | 2025-01-30 |
| Efficacy and Safety of Emodepside in Adults Infected With Trichuris Trichiura and Hookworm Emodepside - Trichuris Trichiura; Infection, Hookworm Infections | Phase 2 | Completed | Jennifer Keiser | 442 | 2021-08-02 | 2022-05-27 |
| Efficacy and Safety of MOX/ALB Co-administration Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Ivermectin 3 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 255 | 2021-06-15 | 2024-01-24 |
| Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL] - Trichuriasis, Ascariasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 536 | 2021-03-01 | 2024-12-05 |
| Albendazole Plus High Dose Ivermectin for Trichuriasis in Pediatric Patients Ivermectin, Albendazole - Trichuris Infection, Helminthiasis | Phase 2 | Completed | Alejandro Krolewiecki | 176 | 2019-10-09 | 2020-07-29 |
Showing 20 of 30. Sign in to see all of them.
Hookworm Infections (14) · Ancylostomiasis (9) · Ascariasis (8) · Helminthiasis (3) · Diarrhea (2) · Enterobiasis (2) · Neglected Diseases (2) · Strongyloidiasis (2) · Adenoviridae Infections (1) · Arenaviridae Infections (1) · Brucellosis (1) · Bunyaviridae Infections (1) · Caliciviridae Infections (1) · Chickenpox (1)
Adenophorea Infections (30) · Enoplida Infections (30) · Nematode Infections (30) · Infections (29) · Parasitic Diseases (29) · Helminthiasis (27) · Secernentea Infections (17) · Strongylida Infections (15) · Ascaridida Infections (8) · Pathological Conditions, Signs and Symptoms (4) · Skin Diseases, Parasitic (4) · Ectoparasitic Infestations (3) · Skin Diseases (3) · Skin Diseases, Infectious (3) · Skin and Connective Tissue Diseases (3)
Albendazole (17) · Ivermectin (8) · Mebendazole (5) · moxidectin (5) · Tablets (4) · emodepside (4) · Bay 44-4400 (2) · oxantel pamoate (2) · oxfendazole (2) · Albumins (1) · Intravital Microscopy (1) · Levamisole (1) · Therapeutics (1)
Jennifer Keiser (10) · Swiss Tropical & Public Health Institute (4) · University Ghent (2) · Alejandro Krolewiecki (1) · Asociacion Benefica Prisma (1) · Centers for Disease Control and Prevention (1) · George Washington University (1) · Institut Pasteur du Cambodge (1) · Kirby Institute (1) · London School of Hygiene and Tropical Medicine (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Mundo Sano Foundation (1) · Natural History Museum, United Kingdom (1) · Oxfendazole Development Group (1) · Oxford University Clinical Research Unit, Vietnam (1)
Tanzania (11) · Côte d’Ivoire (3) · Argentina (2) · Cambodia (2) · Ethiopia (2) · Honduras (2) · Peru (2) · Vietnam (2) · Angola (1) · Australia (1) · Bangladesh (1) · Brazil (1) · Cameroon (1) · Guatemala (1) · Indonesia (1)
Jennifer Keiser, PhD (2) · Jennifer Keiser, Professor (2) · Alejandro J Krolewiecki, MD, PhD (1) · Alejandro Javier Krolewiecki, PhD, MD (1) · Andrea Graham, PhD (1) · Byron Arana, MD (1) · Charles Mwandawiro, PhD (1) · Claude Flamand, Ph.D. (1) · Daniel Paris, MD, PhD (1) · Gabriela Matamoros, PhD, MSc, BSc (1) · Hussein Mbarak, MD (1) · Jacqueline Leung, MA (1) · Jade Benjamin-Chung, PhD MPH (1)
PMID 18775092, PMID 22189084, PMID 25299391, PMID 27266697, PMID 30885157, PMID 31044235, PMID 32405623, PMID 32668456, PMID 33906234, PMID 34191812, PMID 34632308, PMID 34856181, PMID 35217670, PMID 36354034, PMID 37195942, PMID 37195949, PMID 37357904, PMID 38517907, PMID 39108529, PMID 39561184, PMID 39591454, PMID 40032381, PMID 40480665, PMID 40675166, PMID 40975108, PMID 42486129
R01HD108196 (1)