251 completed, 46 unknown, 21 recruiting, 20 not yet recruiting. 93 Not applicable, 62 Phase 2, 56 Phase 3, 40 Phase 1, 28 Phase 4.
Follow Helminthiasis: new trials by email Literature Review of Helminthiasis trials Research Report on Helminthiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxfendazole in Mild Parenchymal Brain Cysticercosis Oxfendazole single dose, Oxfendazole three doses, albendazole plus praziquantel regime - Brain Cysticercosis | Phase 2 / Phase 3 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 544 | 2026-12-01 | 2026-05-01 |
| Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita Emodepside, Albendazole 400 mg - Trichuris Infection | Phase 2 | Not yet recruiting | Jennifer Keiser | 100 | 2026-11-15 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year - Schistosomiasis, Schistosoma Mansoni | Phase 2 / Phase 3 | Not yet recruiting | Rhode Island Hospital | 600 | 2026-11-01 | 2026-08-12 |
| Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras Placebo, Albendazole 400 mg, Albendazole Plus Ivermectin - Trichuriasis, Strongyloidiasis | Phase 3 | Not yet recruiting | Mundo Sano Foundation | 368 | 2026-11-01 | 2026-06-23 |
| Follow-up Assessment of Change in Soil-transmitted Helminths Infection Intensity in Uganda Albendazole 400mg, Ivermectin 3 mg - Ascariasis | Phase 3 | Not yet recruiting | Jennifer Keiser | 450 | 2026-10-01 | 2026-10-14 |
| Better Options for Lymphatic Filariasis Treatment MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole - Lymphatic Filariasis, Scabies | Phase 3 | Recruiting | Medicines Development for Global Health | 5100 | 2026-09-28 | 2026-10-07 |
| One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis Oxfendazole, Triclabendazole - Fascioliasis | Phase 2 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 336 | 2026-08-15 | 2026-06-03 |
| Assessment of Right Ventricular-Pulmonary Arterial Coupling in Schistosomiasis-Associated Pulmonary Arterial Hypertension right heart catheterization for measure pulmonary artery pressure - Schistosomiasis | Not applicable | Not yet recruiting | Sohag University | 50 | 2026-07-01 | 2026-07-16 |
| Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg - Onchocerciasis (River Blindness), Schistosomiasis | Not applicable | Recruiting | Uwemedimo Friday Ekpo | 5760 | 2026-07-01 | 2026-07-16 |
| 5G Remote Robotic Surgery for Hepatic Echinococcosis in High-Altitude Region 5G-based Telerobotic Hepatectomy - Hepatic Echinococcosis | Early Phase 1 | Not yet recruiting | West China Hospital | 10 | 2026-05-01 | 2026-04-24 |
| Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers A mobile app with AI functionality for diagnosing skin-related NTDs - Skin and Connective Tissue Diseases, Neglected Tropical Diseases | Not applicable | Not yet recruiting | Kenya Medical Research Institute | 2420 | 2026-05-01 | 2026-04-02 |
| Prevalence and Molecular Identification of Human Schistosomiasis Molecular phylogenetic and haplotype analysis - Schistosomiasis | Not yet recruiting | Assiut University | 359 | 2026-05-01 | 2026-03-19 | |
| Nanobody-based Schistosomiasis Urine Test Kit Research Because this is an observational study, participants are not assigned an intervention as part of the study. - Schistosomiasis Haematobia | Not yet recruiting | Pemba Ministry of Health Zanzibar | 2500 | 2026-04-01 | 2026-03-30 | |
| Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial Hypertension Pulmonary Arterial Hypertension (PAH) | Not yet recruiting | Caio Júlio César dos Santos Fernandes | 30 | 2026-03-01 | 2026-03-05 | |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis Medical TV Drama Episode (House M.D.) - Neurocysticercosis, Health Literacy | Not applicable | Not yet recruiting | Cephas Health Research Initiative Inc, Ibadan, Nigeria | 60 | 2025-12-15 | 2025-12-04 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Integrating Mental Health Into Neglected Tropical Disease Care in Ghana WHO Essential Care package for mental health and NTDs - Leprosy, Lymphatic Filariases | Not applicable | Not yet recruiting | Liverpool School of Tropical Medicine | 200 | 2025-11-01 | 2025-11-25 |
| IM Bands in Inactive Hepatic CE Cystic Echinococcosis | Recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 100 | 2025-09-23 | 2026-01-12 |
Showing 20 of 368. Sign in to see all of them.
Schistosomiasis (78) · Ancylostomiasis (41) · Elephantiasis, Filarial (41) · Hookworm Infections (39) · Onchocerciasis (35) · Trichuriasis (30) · Echinococcosis (24) · Filariasis (23) · Schistosomiasis haematobia (21) · Neurocysticercosis (20) · Neglected Diseases (19) · Trematode Infections (19) · Malaria (18) · Strongyloidiasis (15)
Infections (361) · Parasitic Diseases (357) · Nematode Infections (172) · Secernentea Infections (161) · Vector Borne Diseases (149) · Trematode Infections (103) · Spirurida Infections (87) · Filariasis (65) · Hemic and Lymphatic Diseases (64) · Cestode Infections (57) · Pathological Conditions, Signs and Symptoms (57) · Mosquito-Borne Diseases (56) · Strongylida Infections (56) · Skin and Connective Tissue Diseases (47)
Albendazole (86) · Ivermectin (47) · Praziquantel (38) · moxidectin (14) · Diethylcarbamazine (13) · Mebendazole (12) · emodepside (9) · oxfendazole (9) · Bay 44-4400 (7) · Tablets (7) · Albumins (6) · Azithromycin (6) · Doxycycline (6) · Therapeutics (4) · Blood Specimen Collection (3)
National Institute of Allergy and Infectious Diseases (NIAID) (35) · Jennifer Keiser (14) · Washington University School of Medicine (13) · Baylor College of Medicine (12) · DBL -Institute for Health Research and Development (12) · London School of Hygiene and Tropical Medicine (10) · Swiss Tropical & Public Health Institute (10) · Leiden University Medical Center (7) · University Ghent (7) · IRCCS Sacro Cuore Don Calabria di Negrar (6) · Medicines Development for Global Health (6) · University Hospitals Cleveland Medical Center (6) · Centre de Recherche Médicale de Lambaréné (5) · Oswaldo Cruz Foundation (5) · Universidad Peruana Cayetano Heredia (5)
United States (31) · Tanzania (30) · Ghana (16) · India (16) · Kenya (16) · Uganda (16) · Brazil (13) · Côte d’Ivoire (13) · Ethiopia (11) · Peru (11) · Senegal (11) · Egypt (10) · Gabon (9) · Cameroon (8) · Italy (8)
Gary Weil, MD (6) · Thomas B Nutman, M.D. (6) · David Diemert, MD (5) · Amy D Klion, M.D. (4) · Bruno Levecke, PhD (4) · Jennifer Keiser, PhD (4) · Ayola Adegnika, MD (3) · David J Diemert, MD (3) · Eric Ottesen, MD (3) · Gary J Weil, MD (3) · Judd L Walson, MD, MPH (3) · Annette Olsen, PhD (2) · Benjamin Koudou, PhD (2) · Christopher King, MD PhD (2)
PMID 11873261, PMID 22610930, PMID 26571311, PMID 32228663, PMID 42848323, PMID 10656038, PMID 19150418, PMID 2022660, PMID 21298114, PMID 23284726, PMID 28464026, PMID 33998661, PMID 35533701, PMID 37262040, PMID 18396361, PMID 18414647, PMID 18495737, PMID 18670219, PMID 18775092, PMID 18809192, PMID 19081121, PMID 19780472, PMID 19802383, PMID 19812401, PMID 20361031, PMID 20705516, PMID 21332573, PMID 21460008, PMID 21572981, PMID 21729382, PMID 22189084, PMID 22633322, PMID 22775568, PMID 22802974, PMID 22971323, PMID 23175561, PMID 23596262, PMID 23675549, PMID 23746776, PMID 23981378, PMID 24063608, PMID 24134221, PMID 24550339, PMID 24603321, PMID 24824051, PMID 24968000, PMID 24999157, PMID 25299391, PMID 25527564, PMID 25624403
2015 (2), 2017 (2), 2008 (1), 2016 (1), 2023 (1), 5UM1AI148373-03 (1), R01AI155739 (1), R01AI184979 (1), R01HD095562 (1), R01HD108196 (1), R01NS054805 (1), R21HD076216 (1), R21NS069275 (1), U01AI066050 (1), U01AI129789 (1)