25 completed, 10 recruiting, 9 unknown, 2 not yet recruiting. 20 Not applicable, 7 Phase 4, 6 Phase 2, 4 Phase 3, 3 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Remote Monitoring of Liver Cirrhosis Patients Liver Cirrhosis | Not yet recruiting | Maastricht University Medical Center | 750 | 2026-05-01 | 2025-09-26 | |
| Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation IMPROVE Risk Model - Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction | Not applicable | Recruiting | Maastricht University Medical Center | 613 | 2026-03-31 | 2026-05-15 |
| Evaluation of a Personalised Survivorship Care Plan App for Patients With Melanoma Digizorg Melanoma app - Melanoma (Skin), Melanoma, Stage II, Stage I | Not applicable | Recruiting | Erasmus Medical Center | 180 | 2025-04-01 | 2025-06-11 |
| Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis Double dosing of beta-lactam antibiotic - Sepsis - to Reduce Mortality in the Intensive Care Unit, Sepsis | Phase 4 | Recruiting | Erasmus Medical Center | 980 | 2025-01-03 | 2025-01-09 |
| Supplemental Screening for Women With Extremely Dense Breast Tissue: the DENSE-2 Trial Contrast-enhanced mammography (CEM), Abbreviated MRI (AB-MRI) - Breast Cancer | Not applicable | Recruiting | C.H. van Gils | 36000 | 2024-11-11 | 2026-05-11 |
| Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone) Pit-picking surgery, Pit-picking surgery with Sinus Laser assisted Closure - Pilonidal Sinus, Pilonidal Disease | Not applicable | Not yet recruiting | dr. IJM Han-Geurts | 482 | 2024-08-28 | 2024-08-29 |
| Preoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breast Cancer Preoperative accelerated partial breast irradiation, Breast conserving surgery, Sentinel node procedure - Breast Cancer | Not applicable | Recruiting | The Netherlands Cancer Institute | 31 | 2024-04-12 | 2026-09-17 |
| Driving Pressure During General Anesthesia for Minimally Invasive Abdominal Surgery (GENERATOR) Intraoperative ventilation with individualized high PEEP titrated to the lowest ΔP with RMs - Postoperative Complications, Surgery | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 1806 | 2023-12-11 | 2025-01-30 |
| Implementation of Online Advance Care Planning Tool for (Hemato-)Oncological Patients Within the Cancer Network Concord Oncology, Advance Care Planning | Recruiting | Erasmus Medical Center | 30 | 2023-10-01 | 2024-04-08 | |
| Telemonitoring and E-Coaching in Hypertension Home blood pressure monitoring (telemonitoring), Standard care - Hypertension | Not applicable | Unknown | Maasstad Hospital | 400 | 2023-04-01 | 2023-04-13 |
| Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy Hybrid DEB approach with drug-eluting balloon, Two-stent strategy - Coronary Artery Disease, Coronary Bifurcation Lesion | Not applicable | Recruiting | Cathreine BV | 500 | 2023-03-21 | 2023-12-15 |
| Folinic Acid for Prevention of Pemetrexed-induced Toxicity Folinic acid - NSCLC, Mesothelioma | Phase 4 | Unknown | Amphia Hospital | 50 | 2023-02-06 | 2023-08-24 |
| Preterm Immune System Development and Response to Immunization Immune System Disorder, Preterm | Unknown | Maastricht University Medical Center | 145 | 2022-12-08 | 2024-03-20 | |
| Optimal Stent Deployment Strategy of Contemporary Stents PCI - Coronary Artery Disease | Not applicable | Recruiting | Albert Schweitzer Hospital | 248 | 2022-09-01 | 2024-02-01 |
| Spatial Location of Breast Cancer Local Recurrence After Mastectomy Mastectomy - Breast Cancer | Unknown | Maastricht Radiation Oncology | 170 | 2021-09-01 | 2023-11-14 | |
| Driving Pressure During General Anesthesia for Open Abdominal Surgery Individualized high PEEP strategy - Postoperative Respiratory Complication | Not applicable | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 1468 | 2019-04-23 | 2025-11-19 |
| Nasal High-Flow in COPD Nasal High Flow Therapy, Standard care - COPD Exacerbation | Not applicable | Recruiting | Marieke Duiverman | 136 | 2018-10-01 | 2024-12-05 |
| Nivolumab Combined With Daratumumab With or Without Low-dose Cyclophosphamide nivolumab-daratumumab, nivolumab-daratumumab with low-dose cyclophosphamide - Myeloma | Phase 2 | Completed | Amsterdam UMC, location VUmc | 62 | 2018-02-21 | 2024-05-22 |
| Traumatic Splenic Injury and Management (SPLENIQ Study) Questionnaires, MRI abdomen - Quality of Life, Spleen Injury | Completed | Elisabeth-TweeSteden Ziekenhuis | 106 | 2017-03-01 | 2022-04-01 | |
| Chronic Ankle Instability, Surgical Repair: Open Versus Closed Surgical stabilization - Chronic Ankle Instability | Not applicable | Completed | Gwendolyn Vuurberg | 41 | 2017-01-01 | 2025-10-03 |
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Malaria (11) · Breast Neoplasms (4) · Coronary Artery Disease (2) · Fever (2) · Hemorrhagic Fever, Ebola (2) · Anemia (1) · Anxiety Disorders (1) · Arthritis, Rheumatoid (1) · Atherosclerosis (1) · Carotid Artery Diseases (1) · Carotid Stenosis (1) · Colitis, Ulcerative (1) · Critical Illness (1) · Crohn Disease (1) · Delirium (1)
fanasil, pyrimethamine drug combination (4) · Artemether, Lumefantrine Drug Combination (3) · Clindamycin (2) · Mefloquine (2) · Standard of Care (2) · fosmidomycin (2) · Albendazole (1) · Artesunate (1) · Cognitive Behavioral Therapy (1) · Cyclophosphamide (1) · Ibuprofen (1) · Imiquimod (1) · Leucovorin (1) · Mastectomy (1) · Mastectomy, Segmental (1)
Netherlands (26) · Gabon (15) · Germany (3) · Italy (2) · Kenya (2) · Mozambique (2) · Switzerland (2) · Benin (1) · Burkina Faso (1) · Nigeria (1) · Portugal (1) · Rwanda (1) · Tanzania (1) · Uganda (1) · Zambia (1)
Michel A. Missinou, PhD (2) · Astrid Scholten, MD PhD (1) · Carla H van Gils, PhD (1) · Carla van Gils, Prof. (1) · Claire-Anne Siegrist, MD (1) · Clara Menendez, MD, PhD (1) · Clemens MF Dirven, Prof. PhD (1) · David van Meenen, PhD (1) · Dirk Domagk, M.D., PhD (1) · Eric-Jan JA van Gorp, MD (1) · Erwin W. Ista, Dr (1) · Gertjan Driessen, Prof MD PhD (1) · Jantien Bolt-Wieringa, MD (1)
PMID 25830326, PMID 26659569, PMID 28647166, PMID 29627147, PMID 10451482, PMID 10764464, PMID 10796771, PMID 1731281, PMID 17331245, PMID 17919718, PMID 17959735, PMID 18008242, PMID 18503714, PMID 18828899, PMID 19586656, PMID 19848610, PMID 19943823, PMID 20361381, PMID 20952254, PMID 21173650, PMID 21345402, PMID 21569596, PMID 22087077, PMID 22177579, PMID 22515681, PMID 22771223, PMID 22914404, PMID 23094124, PMID 23117059, PMID 23175561, PMID 23489374, PMID 23843155, PMID 24201682, PMID 24353124, PMID 24436334, PMID 24550339, PMID 25220842, PMID 25247709, PMID 25247995, PMID 25273854, PMID 25915616, PMID 26055847, PMID 26248510, PMID 26869532, PMID 26905278, PMID 26966551, PMID 26978384, PMID 27357200, PMID 27940685, PMID 28434944
2015 (1)