32 completed, 3 recruiting, 2 not yet recruiting, 2 terminated. 9 Not applicable, 8 Phase 3, 6 Phase 2, 5 Phase 4, 2 Phase 1.
Follow Elephantiasis, Filarial: new trials by email Literature Review of Elephantiasis, Filarial trials Research Report on Elephantiasis, Filarial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Better Options for Lymphatic Filariasis Treatment MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole - Lymphatic Filariasis, Scabies | Phase 3 | Recruiting | Medicines Development for Global Health | 5100 | 2026-09-28 | 2026-10-07 |
| Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg - Onchocerciasis (River Blindness), Schistosomiasis | Not applicable | Recruiting | Uwemedimo Friday Ekpo | 5760 | 2026-07-01 | 2026-07-16 |
| Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers A mobile app with AI functionality for diagnosing skin-related NTDs - Skin and Connective Tissue Diseases, Neglected Tropical Diseases | Not applicable | Not yet recruiting | Kenya Medical Research Institute | 2420 | 2026-05-01 | 2026-04-02 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Integrating Mental Health Into Neglected Tropical Disease Care in Ghana WHO Essential Care package for mental health and NTDs - Leprosy, Lymphatic Filariases | Not applicable | Not yet recruiting | Liverpool School of Tropical Medicine | 200 | 2025-11-01 | 2025-11-25 |
| Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug AWZ1066S, Placebo - Filariasis, Lymphatic, Onchocerciasis | Phase 1 | Terminated | Liverpool School of Tropical Medicine | 30 | 2021-12-10 | 2023-09-21 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Adjunctive Ivermectin Mass Drug Administration for Malaria Control Ivermectin, Placebo, Dihydroartemisinin-piperaquine - Malaria,Falciparum, Neglected Tropical Diseases | Phase 3 | Unknown | London School of Hygiene and Tropical Medicine | 24000 | 2021-05-03 | 2022-02-24 |
| Moxidectin for LF, Cote d'Ivoire (DOLF) Ivermectin, Diethylcarbamazine, Albendazole - Lymphatic Filariasis | Phase 3 | Completed | Washington University School of Medicine | 164 | 2020-08-20 | 2026-01-29 |
| Spontaneous Antigenemia in Loiasis No intervention - Loiasis, Lymphatic Filariasis | Completed | Washington University School of Medicine | 86 | 2020-01-23 | 2026-08-21 | |
| A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in India Doxycycline, Placebo - Lymphedema, Lymphatic Filariasis | Phase 3 | Completed | The Task Force for Global Health | 235 | 2019-01-15 | 2021-06-24 |
| Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Albendazole on Day 1, Ivermectin on Day 1, Diethylcarbamazine on day 1 - Trachoma, Yaws | Phase 3 | Completed | Lihir Medical Centre | 20000 | 2018-10-01 | 2019-02-28 |
| PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs ) Azithromycin, Albendazole, Ivermectin - Lymphatic Filariasis, Yaws | Phase 2 | Completed | Lihir Medical Centre | 42 | 2018-09-01 | 2019-02-28 |
| A 24 Month Study, to Compare the Efficacy of Doxycycline vs. Placebo for Improving Filarial Lymphedema in Mali Doxycycline, Placebo - Lymphedema, Lymphatic Filariasis | Phase 3 | Completed | The Task Force for Global Health | 220 | 2018-06-19 | 2021-06-24 |
| Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia Leprosy, Buruli Ulcer | Completed | London School of Hygiene and Tropical Medicine | 56285 | 2018-06-14 | 2024-06-10 | |
| A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in Sri Lanka Doxycycline, Placebo - Lymphedema, Lymphatic Filariasis | Phase 3 | Completed | The Task Force for Global Health | 219 | 2018-02-16 | 2021-03-17 |
| Prevalence of LF Infection in Districts Not Included in LF Control Activities Diagnosis of lymphatic filariasis, Diagnosis of lymphatic Filariasis and onchocerciasis, DEC Patch - Lymphatic Filariases, Onchocerciasis | Completed | Noguchi Memorial Institute for Medical Research | 3736 | 2018-01-21 | 2018-10-11 | |
| Prevalence Studies After Triple Drug Therapy for Lymphatic Filariasis 2 drug dose - DA, 3 drug dose - IDA - Lymphatic Filariases | Completed | Washington University School of Medicine | 20092 | 2017-10-18 | 2020-12-31 | |
| Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji 3 drug dose - IDA, 3 drug dose - IDA with second dose of ivermectin, 2 drug dose - DA - Lymphatic Filariases, Scabies | Not applicable | Completed | Washington University School of Medicine | 4773 | 2017-07-13 | 2020-12-31 |
| Twice Yearly Treatment for the Control of LF 400 μg/kg Ivermectin + 400 mg Albendazole - Lymphatic Filariasis, Helminth Infection | Phase 4 | Completed | Noguchi Memorial Institute for Medical Research | 1462 | 2017-05-19 | 2020-02-26 |
Showing 20 of 41. Sign in to see all of them.
Filariasis (7) · Onchocerciasis (7) · Neglected Diseases (6) · Scabies (5) · Yaws (5) · Trachoma (4) · Buruli Ulcer (3) · Infections (3) · Leprosy (3) · Lymphedema (3) · Malaria (3) · Strongyloidiasis (3) · HIV Infections (2) · Parasitic Diseases (2)
Helminthiasis (41) · Hemic and Lymphatic Diseases (41) · Lymphatic Diseases (41) · Mosquito-Borne Diseases (41) · Nematode Infections (41) · Secernentea Infections (41) · Spirurida Infections (41) · Vector Borne Diseases (40) · Parasitic Diseases (39) · Infections (38) · Lymphedema (38) · Filariasis (34) · Skin Diseases (14) · Skin Diseases, Infectious (14) · Skin and Connective Tissue Diseases (13)
Albendazole (19) · Ivermectin (17) · Diethylcarbamazine (9) · Azithromycin (4) · Doxycycline (4) · Albumins (3) · Intravital Microscopy (1) · Mass Drug Administration (1) · Mebendazole (1) · Mental Health (1) · Praziquantel (1) · moxidectin (1)
Washington University School of Medicine (9) · London School of Hygiene and Tropical Medicine (4) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · University Hospitals Cleveland Medical Center (4) · The Task Force for Global Health (3) · Centre d'Appui à la lutte contre la Maladie (2) · Lihir Medical Centre (2) · Liverpool School of Tropical Medicine (2) · Noguchi Memorial Institute for Medical Research (2) · Colorado State University (1) · DBL -Institute for Health Research and Development (1) · Emory University (1) · Indian Council of Medical Research (1) · Institut Pasteur du Cambodge (1) · Kenya Medical Research Institute (1)
India (8) · Papua New Guinea (6) · Côte d’Ivoire (4) · Fiji (3) · Indonesia (3) · Mali (3) · Ethiopia (2) · Ghana (2) · Haiti (2) · Liberia (2) · Nigeria (2) · United States (2) · Burkina Faso (1) · Cambodia (1) · Cameroon (1)
Eric Ottesen, MD (3) · Gary J Weil, MD (3) · Gary Weil, MD (3) · Peter U Fischer, PhD (2) · Philip Budge, MD, PhD (2) · Aboulaye Miete, MD (1) · Andrew Steer, PhD (1) · Anna R Last, MBChB PhD (1) · Benjamin Koudou, PhD (1) · Brian D. Foy, PhD (1) · Catherine Bjerum, MD, MPH (1) · Christopher King, MD PHD (1) · Christopher King, MD PhD (1) · Christopher L King, MD PhD (1)
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