1649 completed, 241 unknown, 111 recruiting, 105 terminated. 460 Not applicable, 432 Phase 2, 422 Phase 1, 368 Phase 3, 269 Phase 4.
Follow Parasitic Diseases: new trials by email Literature Review of Parasitic Diseases trials Research Report on Parasitic Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren Monthly DP, Quarterly DP - Malaria, Asymptomatic Malaria | Phase 3 | Not yet recruiting | Indiana University | 1500 | 2028-01-01 | 2026-09-01 |
| Assessment of the Prevalence of Rheumatic Heart Disease in School Settings in Mayotte and the Acquisition of Ultrasound Sequences Guided by Artificial Intelligence Ultrasound performed bycardiologis for diagnosis of rheumatic heart disease - Rheumatic Heart Diseases, Scabies | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de la Réunion | 900 | 2027-10-01 | 2026-10-29 |
| Permethrin-Treated Baby Wraps for Malaria Prevention in Refugee Settings Factory-treated lesu, Soaked lesu, Untreated lesu - Malaria (Plasmodium Falciparum), Malaria Incidence | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1350 | 2027-09-01 | 2026-10-29 |
| Study to Assess Safety and Clinical Responses With Coartem® Baby Dispersible Tablets in Paediatric Patients Weighing 2 to <5 kg With Uncomplicated Malaria Coartem® Baby - Malaria | Phase 4 | Not yet recruiting | Novartis Pharmaceuticals | 20 | 2027-06-18 | 2026-07-20 |
| Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina Faso PfSPZ-LARC2 Vaccine, PfSPZ Challenge, Normal Saline - Malaria (Plasmodium Falciparum) | Phase 1 | Not yet recruiting | Sanaria Inc. | 45 | 2027-03-01 | 2026-07-31 |
| Spatial Emanator Deployment Strategies for Malaria Control in Papua New Guinea Spatial emanator outdoor, Spatial emanator indoor - Malaria | Not applicable | Not yet recruiting | Macfarlane Burnet Institute for Medical Research and Public Health Ltd | 4350 | 2027-02-01 | 2026-11-10 |
| Insecticide-Treated Baby Wraps for the Prevention of Malaria Permethrin-treated lesu, Etofenprox-treated lesu, Untreated lesu - Malaria (Plasmodium Falciparum), Malaria Incidence | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1296 | 2027-01-01 | 2026-08-19 |
| HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence: Infant Versus Standard Formulation ivermectin infant formula preparation, Standard ivermectin 3mg tablet - Scabies | Phase 1 | Suspended | Murdoch Childrens Research Institute | 52 | 2027-01-01 | 2026-10-09 |
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in Pakistan Virtual Reality - Cutaneous Leishmaniasis, Pain | Not applicable | Not yet recruiting | Stanford University | 15 | 2027-01-01 | 2026-10-05 |
| An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health Nifurtimox (BAYA2502) - Chagas Disease | Not yet recruiting | Bayer | 50 | 2026-12-31 | 2026-07-06 | |
| Nitazoxanide for Treatment of Cryptosporidium in Children Nitazoxanide, Placebo - Cryptosporidiosis | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 480 | 2026-12-30 | 2026-09-28 |
| Integrating the Guardian Spatial Emanator Within AVENIR II Spatial Emanator - Malaria | Not applicable | Not yet recruiting | University of California, San Francisco | 150000 | 2026-12-01 | 2026-07-22 |
| Oxfendazole in Mild Parenchymal Brain Cysticercosis Oxfendazole single dose, Oxfendazole three doses, albendazole plus praziquantel regime - Brain Cysticercosis | Phase 2 / Phase 3 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 544 | 2026-12-01 | 2026-05-01 |
| This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria SJ733/TQ placebo, CQ/TQ Placebo, CQ/TQ - Malaria, Malaria Vivax | Phase 2 | Not yet recruiting | R. Kiplin Guy | 104 | 2026-12-01 | 2026-10-21 |
| Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita Emodepside, Albendazole 400 mg - Trichuris Infection | Phase 2 | Not yet recruiting | Jennifer Keiser | 100 | 2026-11-15 | 2026-08-14 |
| Positron Emission Tomography and Organ-Specific Changes in Participants Co-Enrolled in NIH Studies of Plasmodium Vivax Controlled Human Malaria Infection 18F-fluorodeoxyglucose-positron emission tomography/computed tomography scan - Healthy Volunteer, Malaria | Not applicable | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 45 | 2026-11-15 | 2026-11-10 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Malaria CVD 36000; Gates INV090205 PfSPZ Challenge (NF54), Wearable Biosensor Devices, Placebo - Malaria (Plasmodium Falciparum) | Phase 1 | Not yet recruiting | University of Maryland, Baltimore | 32 | 2026-11-01 | 2026-09-09 |
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year - Schistosomiasis, Schistosoma Mansoni | Phase 2 / Phase 3 | Not yet recruiting | Rhode Island Hospital | 600 | 2026-11-01 | 2026-08-12 |
Showing 20 of 2291. Sign in to see all of them.
Malaria (1137) · Malaria, Falciparum (451) · Malaria, Vivax (123) · Leishmaniasis, Cutaneous (102) · Schistosomiasis (78) · Anemia (77) · Chagas Disease (73) · HIV Infections (72) · Leishmaniasis (71) · Leishmaniasis, Visceral (61) · Scabies (51) · Diarrhea (44) · Disease (43) · Infections (42)
Infections (2249) · Protozoan Infections (1834) · Vector Borne Diseases (1800) · Mosquito-Borne Diseases (1419) · Helminthiasis (332) · Euglenozoa Infections (301) · Pathological Conditions, Signs and Symptoms (290) · Skin and Connective Tissue Diseases (271) · Skin Diseases (267) · Skin Diseases, Infectious (264) · Skin Diseases, Parasitic (257) · Malaria (244) · Pathologic Processes (205) · Nematode Infections (172)
Artemether, Lumefantrine Drug Combination (165) · fanasil, pyrimethamine drug combination (100) · Albendazole (96) · Primaquine (93) · Chloroquine (88) · Artesunate (74) · Ivermectin (72) · Amodiaquine (57) · Praziquantel (42) · miltefosine (39) · amodiaquine, artesunate drug combination (38) · Azithromycin (37) · tafenoquine (34) · Mefloquine (29) · Saline Solution (29)
National Institute of Allergy and Infectious Diseases (NIAID) (180) · University of Oxford (130) · London School of Hygiene and Tropical Medicine (125) · Medicines for Malaria Venture (59) · GlaxoSmithKline (56) · U.S. Army Medical Research and Development Command (53) · University of California, San Francisco (40) · Centers for Disease Control and Prevention (39) · Drugs for Neglected Diseases (38) · Institute of Tropical Medicine, Belgium (37) · Novartis Pharmaceuticals (33) · Sanaria Inc. (29) · Menzies School of Health Research (27) · Radboud University Medical Center (26) · PATH (25)
United States (270) · Kenya (138) · Uganda (132) · Tanzania (125) · Burkina Faso (122) · Mali (107) · Brazil (100) · United Kingdom (85) · Ghana (80) · Thailand (60) · India (58) · Democratic Republic of the Congo (57) · Ethiopia (56) · France (54) · Gabon (52)
Patrick E Duffy, M.D. (14) · Shyam Sundar, MD (9) · Grant Dorsey, MD, PhD (8) · Kassoum Kayentao, MD, MPH, PhD (7) · Rick M Fairhurst, M.D. (7) · Salim Abdulla, MD, PhD (7) · Teun Bousema, PhD (7) · Francois Nosten, MD (6) · Gary Weil, MD (6) · James McCarthy, Prof (6) · Sara A Healy, M.D. (6)
PMID 39324693, PMID 23433102, PMID 34585740, PMID 25421474, PMID 26666916, PMID 39787798, PMID 28081133, PMID 39377226, PMID 11873261, PMID 22610930, PMID 26571311, PMID 28193647, PMID 28379954, PMID 28495354, PMID 31932368, PMID 32228663, PMID 33289099, PMID 35664997, PMID 35945599, PMID 36534705, PMID 37790581, PMID 38115002, PMID 38418982, PMID 40245769, PMID 41014333, PMID 41176969, PMID 42848323, PMID 10656038, PMID 16928995, PMID 17845167, PMID 18828899, PMID 19150418, PMID 19558654, PMID 19641203, PMID 2022660, PMID 21298114, PMID 21443960, PMID 21849081, PMID 22993389, PMID 23284726, PMID 23526949, PMID 23877689, PMID 23899517, PMID 23962071, PMID 23996605, PMID 24035558, PMID 24206649, PMID 24885993, PMID 24970846, PMID 25211344
2016 (7), 2015 (6), 2019 (6), R01HD068174 (4), 2017 (3), 2023 (3), R01AI141444 (3), U19AI065866 (3), 2018 (2), P01HD059454 (2), R01AI110478 (2), R01NS074409 (2), U01AI065683 (2), U01AI068632 (2), U01CI000211 (2)