27 completed, 6 withdrawn, 2 terminated, 1 active not recruiting. 20 Phase 4, 10 Not applicable, 4 Phase 3, 2 Phase 2, 1 Phase 1.
Follow Trachoma: new trials by email Literature Review of Trachoma trials Research Report on Trachoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Impact of Oral Ivermectin on Musca Sorbens Flies, Putative Vector of Trachoma Ivermectin - Survival of Flies Developing in Faecal Samples | Phase 4 | Not yet recruiting | London School of Hygiene and Tropical Medicine | 12 | 2026-10-05 | 2026-10-30 |
| RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs) B-RAP, BLTR - Trachoma, Eye Diseases | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 1000 | 2026-01-13 | 2026-04-13 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) Azithromycin mass treatment, Azithromycin targeted treatment - Trachoma | Phase 4 | Withdrawn | Emory University | 2025-06-01 | 2025-07-16 | |
| Azithromycin Reduction to Reach Elimination of Trachoma B Azithromycin - Trachoma | Phase 4 | Withdrawn | University of California, San Francisco | 2024-10-01 | 2026-03-13 | |
| Enhancing the A in SAFE for Trachoma Azithromycin for Routine Community-wide MDA, Two Additional Rounds of Azithromycin for Children, Azithromycin for Second Community-wide MDA - Trachoma | Phase 4 | Completed | Emory University | 34630 | 2022-05-04 | 2024-02-29 |
| Kebele Elimination of Trachoma for Ocular Health Azithromycin - Trachoma | Phase 4 | Active not recruiting | University of California, San Francisco | 320000 | 2022-02-07 | 2025-10-23 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Azithromycin Reduction to Reach Elimination of Trachoma Azithromycin - Trachoma | Phase 4 | Completed | University of California, San Francisco | 3931 | 2021-05-29 | 2026-03-25 |
| Safety and Immunogenicity of a Chlamydia Vaccine CTH522 CTH522-CAF01 IM, CTH522-CAF09b IM, CTH522 ID - Trachoma | Phase 1 | Completed | Statens Serum Institut | 65 | 2020-02-17 | 2024-08-22 |
| Smartphone App for Taking Images of Conjunctivae TOFTEE - Trachoma | Not applicable | Terminated | London School of Hygiene and Tropical Medicine | 125 | 2019-07-08 | 2022-08-22 |
| App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders Inter-grader agreement (IGA) app - Trachoma | Not applicable | Terminated | London School of Hygiene and Tropical Medicine | 32 | 2019-07-08 | 2022-08-22 |
| Testing Insect Repellents Against Musca Sorbens, the Vector of Trachoma IR3535, Permethrin lower dose, Permethrin higher dose - Trachoma | Phase 2 | Completed | London School of Hygiene and Tropical Medicine | 64 | 2019-01-10 | 2020-04-08 |
| Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Albendazole on Day 1, Ivermectin on Day 1, Diethylcarbamazine on day 1 - Trachoma, Yaws | Phase 3 | Completed | Lihir Medical Centre | 20000 | 2018-10-01 | 2019-02-28 |
| Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso Azithromycin, Amoxicillin, Cotrimoxazole - Child Development | Phase 4 | Completed | University of California, San Francisco | 252 | 2017-07-04 | 2023-03-02 |
| Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction - Amblyopia, Myopia | Withdrawn | Université de Montréal | 2016-01-01 | 2016-12-02 | ||
| Sanitation, Water, and Instruction in Face-washing for Trachoma I/II Water, sanitation, and hygiene (WASH) intervention, Standard of care WASH intervention, Azithromycin - Trachoma | Phase 3 | Completed | University of California, San Francisco | 47605 | 2015-12-05 | 2026-06-04 |
| Mortality Reduction After Oral Azithromycin: Morbidity Study Azithromycin, Placebo - Childhood Mortality | Phase 4 | Completed | University of California, San Francisco | 72000 | 2014-11-01 | 2021-03-17 |
| Nepal Elimination of Trachoma Study Azithromycin - Trachoma | Phase 2 / Phase 3 | Withdrawn | University of California, San Francisco | 2014-08-01 | 2015-05-21 | |
| Water Uptake for Health in Amhara Pilot instruction in soap-making and hygiene education - Trachoma | Not applicable | Completed | University of California, San Francisco | 4068 | 2014-04-01 | 2021-06-29 |
| Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis azithromycin, ivermectin, albendazole - Trachoma, Lymphatic Filariasis | Phase 4 | Withdrawn | Emory University | 2014-02-01 | 2014-05-22 |
Showing 20 of 38. Sign in to see all of them.
Chlamydia Infections (6) · Trichiasis (6) · Bacterial Infections (4) · Elephantiasis, Filarial (4) · Eye Diseases (3) · Infections (2) · Neglected Diseases (2) · Amblyopia (1) · Astigmatism (1) · Cataract (1) · Communicable Diseases (1) · Corneal Opacity (1) · Diarrhea (1) · Glaucoma (1)
Bacterial Infections and Mycoses (38) · Chlamydiaceae Infections (38) · Conjunctival Diseases (38) · Conjunctivitis (38) · Conjunctivitis, Bacterial (38) · Corneal Diseases (38) · Eye Infections (38) · Eye Infections, Bacterial (38) · Gram-Negative Bacterial Infections (38) · Infections (36) · Eye Diseases (35) · Bacterial Infections (34) · Chlamydia Infections (32) · Communicable Diseases (6) · Eyelid Diseases (6)
Azithromycin (18) · Ivermectin (4) · Albendazole (3) · Permethrin (2) · Water (2) · Amoxicillin (1) · Amyloid (1) · Diethylcarbamazine (1) · Educational Status (1) · Fluorometholone (1) · Hair Removal (1) · Health (1) · Hygiene (1) · Immunoglobulin A (1) · Lubricant Eye Drops (1)
University of California, San Francisco (13) · Johns Hopkins University (7) · London School of Hygiene and Tropical Medicine (7) · Emory University (3) · Baskent University (1) · Centre d'Appui à la lutte contre la Maladie (1) · Laboratoires Thea (1) · Lihir Medical Centre (1) · Statens Serum Institut (1) · University of North Carolina, Chapel Hill (1) · University of Pennsylvania (1) · Université de Montréal (1)
United States (13) · Ethiopia (11) · Tanzania (5) · United Kingdom (5) · Niger (3) · Burkina Faso (1) · Democratic Republic of the Congo (1) · Haiti (1) · Malawi (1) · Mali (1) · Mozambique (1) · Nepal (1) · Papua New Guinea (1) · South Sudan (1) · Turkey (Türkiye) (1)
Tom Lietman, MD (3) · Catherine Oldenburg, ScD, MPH (2) · Elodie Lebas, RN (2) · Emily Gower, PhD (2) · Emma Harding-Esch (2) · Jeremy D Keenan, MD, MPH (2) · Julius Schachter, PhD (2) · Kieran S O'Brien, MPH (2) · Matthew J Burton, PhD FRCOphth (2) · Paul Emerson, PhD (2) · Sheila K West (2) · Sheila K West, PhD (2) · Thomas M Lietman, MD (2) · Tom M Lietman, MD (2) · Abdou Amza, MD (1)
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5UG1EY030833 (2), R01AI048789 (2), 1UG1EY028088 (1), 1UG1EY036891 (1), K23EY019881 (1), U10EY022584 (1), U10EY023939 (1)