7 completed, 3 unknown, 1 recruiting, 1 withdrawn. 12 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 7, Unknown 3, Recruiting 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 4, Recruiting 1 |
Follow Necrotizing Enterocolitis: new trials by email Literature Review of Necrotizing Enterocolitis trials Research Report on Necrotizing Enterocolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Clinical Study of Chondroitin Sulfate for Treatment of NEC Chondroitin sulfate - Necrotizing Enterocolitis, Intestinal Ischemia | Phase 1 | Withdrawn | Indiana University | 2025-01-01 | 2025-10-10 | |
| Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC) ST266 - Necrotizing Enterocolitis | Phase 1 / Phase 2 | Recruiting | Noveome Biotherapeutics, formerly Stemnion | 36 | 2024-08-19 | 2026-04-13 |
| Efficacy Of Oral Melatonin To Prevent Necrotizing Enterocolitis Melatonin 6 MG, Breast Milk - Necrotizing Enterocolitis | Phase 1 / Phase 2 | Completed | Ilocos Training and Regional Medical Center | 100 | 2021-03-01 | 2024-06-20 |
| Simulated Amniotic Fluid Solution in Neonates Recovering From GIT Surgeries SAFE group, placebo group - Necrotizing Enterocolitis | Phase 1 | Unknown | Rania Ali El-Farrash | 40 | 2015-07-01 | 2017-10-05 |
| Simulated Amniotic Fluid In Preventing Feeding Intolerance and Necrotizing Enterocolitis VLBW Neonates simulated amniotic fluid 20cc/kg/day enterally, distilled water - Necrotizing Enterocolitis | Phase 1 | Unknown | Rania Ali El-Farrash | 40 | 2014-03-01 | 2015-04-01 |
| STP206 for the Prevention of Necrotizing Enterocolitis (NEC) STP206, Control - Necrotizing Enterocolitis | Phase 1 | Completed | Leadiant Biosciences, Inc. | 103 | 2014-01-30 | 2020-03-24 |
| Enteral Administration of Docosahexaenoic Acid to Prevent Necrotizing Enterocolitis in Preterm Neonates Docosahexaenoic acid (DHA), Placebo - Necrotizing Enterocolitis | Phase 1 / Phase 2 | Completed | Coordinación de Investigación en Salud, Mexico | 225 | 2012-10-01 | 2021-03-24 |
| Metronidazole Pharmacokinetics (PK) in Premature Infants Metronidazole - Serious Systemic Infections, Necrotizing Enterocolitis | Phase 1 | Completed | Michael Cohen-Wolkowiez | 24 | 2011-01-01 | 2014-02-06 |
| Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates Umbilical Cord Blood Infusion, Intravenous Infusion of Peripheral Blood or its Components - Anemia, Neonatal, Intracranial Hemorrhages | Phase 1 | Unknown | Pomeranian Medical University Szczecin | 40 | 2010-10-01 | 2014-01-31 |
| Enteral Granulocyte Colony Stimulating Factor and Erythropoietin Early in Life Increases Feeding Tolerance in Preterm Infants: A Randomized Controlled Trial recombinant human G-CSF, and rhEPO, rh G-CSF, rh EPO - Feeding Intolerance, Necrotizing Enterocolitis | Phase 1 / Phase 2 | Completed | Ain Shams University | 93 | 2010-01-01 | 2011-09-27 |
| Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections meropenem - Necrotizing Enterocolitis, Intra-abdominal Infection | Phase 1 / Phase 2 | Completed | The Emmes Company, LLC | 200 | 2008-06-01 | 2023-04-25 |
| Effects of Delayed Cord Clamping in Very Low Birth Weight Infants delayed cord clamping - Bronchopulmonary Dysplasia, Necrotizing Enterocolitis | Phase 1 | Completed | University of Rhode Island | 72 | 2003-08-01 | 2015-11-30 |
Enterocolitis, Necrotizing (12) · Bronchopulmonary Dysplasia (2) · Anemia, Neonatal (1) · Central Nervous System Diseases (1) · Hematologic Diseases (1) · Infant, Newborn, Diseases (1) · Infant, Premature, Diseases (1) · Intraabdominal Infections (1) · Intracranial Hemorrhages (1) · Lung Diseases (1) · Motor Skills Disorders (1) · Neonatal Sepsis (1) · Premature Birth (1) · Respiratory Distress Syndrome, Newborn (1) · Retinal Diseases (1)
Digestive System Diseases (12) · Enterocolitis (12) · Gastroenteritis (12) · Gastrointestinal Diseases (12) · Intestinal Diseases (12) · Infections (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Inflammation (2) · Lung Injury (2) · Respiratory Tract Diseases (2) · Systemic Inflammatory Response Syndrome (2) · Ventilator-Induced Lung Injury (2) · Anemia (1)
Chondroitin Sulfates (1) · Docosahexaenoic Acids (1) · Fatty Acids, Omega-3 (1) · Melatonin (1) · Meropenem (1) · Metronidazole (1) · Milk, Human (1) · Sunflower Oil (1) · Umbilical Cord Clamping (1)
Rania Ali El-Farrash (2) · Ain Shams University (1) · Coordinación de Investigación en Salud, Mexico (1) · Ilocos Training and Regional Medical Center (1) · Indiana University (1) · Leadiant Biosciences, Inc. (1) · Michael Cohen-Wolkowiez (1) · Noveome Biotherapeutics, formerly Stemnion (1) · Pomeranian Medical University Szczecin (1) · The Emmes Company, LLC (1) · University of Rhode Island (1)
United States (6) · Egypt (2) · Mexico (1) · Philippines (1) · Poland (1)
Rania A El-Farrash, MD (2) · Boguslaw Machalinski, MD, PhD, BSc (1) · Daisy Evangeline C Garcia, MD (1) · Danny Benjamin, MD, PhD, MPH (1) · Jacek Rudnicki, MD, PhD, BSc (1) · Judith S Mercer, PhD, CNM (1) · Mariela Bernabe-Garcia, PhD (1) · Michael Cohen-wolkowiez, MD (1) · Michael S Caplan, MD (1) · Milosz Piotr Kawa, MD, PhD (1) · Navid P Roodaki, MD (1)
PMID 22955430, PMID 23587979, PMID 25155966, PMID 26547399, PMID 26643677, PMID 33671220
R01NR010015 (1)