61 completed, 37 unknown, 11 terminated, 7 active not recruiting. 40 Not applicable, 17 Phase 2, 12 Phase 1, 12 Phase 3, 3 Phase 4.
Follow Necrotizing Enterocolitis: new trials by email Literature Review of Necrotizing Enterocolitis trials Research Report on Necrotizing Enterocolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fecal Calprotectin in Breastfed vs Formula-Fed Preterm Infants and NEC Necrotizing Enterocolitis, Premature | Not yet recruiting | Assiut University | 112 | 2026-09-03 | 2026-09-10 | |
| Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital Necrotizing Enterocolitis, Intestinal Atresia | Not yet recruiting | Assiut University | 120 | 2026-05-01 | 2026-04-13 | |
| Investigation of Allergen Sensitization in Newborn Babies Diagnosed With Necrotizing Enterocolitis. skin prick test - Necrotizing Enterocolitis, Allergy | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 130 | 2026-04-01 | 2026-05-01 |
| Application of Transcriptome Sequencing Combined With Family-Based Whole Genome Sequencing in Improving Precise Diagnosis of Critically Ill Newborns in Northeast China Whole genome sequencing analysis - Necrotizing Enterocolitis | Not yet recruiting | The First Hospital of Jilin University | 1000 | 2025-06-01 | 2025-05-25 | |
| Study of Normal Intestinal Development and Disease in Premature and Term Neonates NEC, Necrotizing Enterocolitis | Recruiting | Boston Children's Hospital | 100 | 2025-03-17 | 2026-03-27 | |
| Necrotizing Enterocolitis and Bowel Perforation in Very Preterm Infants - Long-term Follow up Necrotizing Enterocolitis, Intestinal Perforation | Not yet recruiting | University Hospital of North Norway | 150 | 2025-02-01 | 2025-01-03 | |
| Phase I Clinical Study of Chondroitin Sulfate for Treatment of NEC Chondroitin sulfate - Necrotizing Enterocolitis, Intestinal Ischemia | Phase 1 | Withdrawn | Indiana University | 2025-01-01 | 2025-10-10 | |
| Milk Temperature Control and Necrotizing Enterocolitis Risk in Extremely Preterm Infants thermostatic feeding, control - Necrotizing Enterocolitis, Preterm | Not applicable | Active not recruiting | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 250 | 2024-09-01 | 2025-04-03 |
| Impact of Standardized Skin-to-Skin Care on Clinical Outcomes in Infants Born ≤ 32 Weeks: A Multicenter Study skin to skin contact care - Premature, Skin to Skin Contact | Not applicable | Recruiting | Baskent University Ankara Hospital | 120 | 2024-09-01 | 2024-11-04 |
| Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC) ST266 - Necrotizing Enterocolitis | Phase 1 / Phase 2 | Recruiting | Noveome Biotherapeutics, formerly Stemnion | 36 | 2024-08-19 | 2026-04-13 |
| Intestinal Perfusion After Feeding in Preterm and Term Infants Evaluation of intestinal perfusion with color Doppler abdominal ultrasound before and after feeding. - Premature, Necrotizing Enterocolitis | Unknown | The Hospital for Sick Children | 20 | 2024-04-02 | 2024-03-20 | |
| Qualitative Study of Surgeons With Prospective Patient Follow-up Necrotizing Enterocolitis | Recruiting | University Hospital Southampton NHS Foundation Trust | 75 | 2024-01-01 | 2024-04-18 | |
| PrePhage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants Fecal Filtrate Transfer, Placebo - Necrotizing Enterocolitis, Microbial Substitution | Early Phase 1 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 20 | 2023-11-07 | 2024-11-15 |
| The Effect of Probiotics Added to the Mother's Diet on Preterm Babies Probiotic Product Supplement - Preterm, Necrotizing Enterocolitis | Not applicable | Unknown | Harran University | 50 | 2023-11-01 | 2023-11-07 |
| PUFAs in Preterm Infants Necrotizing Enterocolitis, Intraventricular Hemorrhage | Unknown | The First Hospital of Jilin University | 600 | 2023-09-21 | 2023-09-21 | |
| RIC-NEC Randomized Controlled Trial Remote ischemic conditioning (RIC) + Standard of Care for NEC, Standard of Care for NEC - Necrotizing Enterocolitis | Phase 2 | Completed | The Hospital for Sick Children | 86 | 2023-02-09 | 2026-11-03 |
| Human Milk-derived Fortification in Preterm Infants Human milk-derived HMF, bovine milk-derived HMF - Postnatal Growth Restriction, Necrotizing Enterocolitis | Not applicable | Unknown | University of Calgary | 42 | 2023-01-15 | 2022-11-07 |
| Analysis of Integrated Clinical, Laboratory and Prognostic Data of Neonates With Necrotizing Enterocolitis Observational retrospective cohort study - Necrotizing Enterocolitis | Completed | Sixth Affiliated Hospital, Sun Yat-sen University | 400 | 2023-01-01 | 2026-03-02 | |
| Effect of Oral N-Acetyl Cysteine in Prevention of Necrotizing Enterocolitis in Preterm Neonates With Feeding Intolerance oral n-acetyl cysteine, placebo - Preterm Neonates and Feeding Intolerance, Necrotizing Enterocolitis | Phase 4 | Unknown | Ain Shams University | 100 | 2023-01-01 | 2024-01-12 |
| Probiotic Supplementation in Extremely Preterm Infants in Scandinavia ProPrems - Necrotizing Enterocolitis, Death | Not applicable | Recruiting | Region Stockholm | 1600 | 2022-12-16 | 2023-10-16 |
Showing 20 of 133. Sign in to see all of them.
Enterocolitis, Necrotizing (133) · Premature Birth (44) · Sepsis (15) · Neonatal Sepsis (10) · Bronchopulmonary Dysplasia (8) · Anemia (5) · Intestinal Perforation (5) · Ductus Arteriosus, Patent (4) · Breast Feeding (3) · Cholestasis (3) · Enterocolitis (3) · Hyperphagia (3) · Infant, Newborn, Diseases (3) · Intestinal Atresia (3) · Intestinal Obstruction (3)
Digestive System Diseases (133) · Gastroenteritis (133) · Gastrointestinal Diseases (132) · Intestinal Diseases (132) · Enterocolitis (130) · Female Urogenital Diseases and Pregnancy Complications (45) · Obstetric Labor Complications (45) · Pregnancy Complications (45) · Urogenital Diseases (45) · Obstetric Labor, Premature (44) · Pathological Conditions, Signs and Symptoms (40) · Pathologic Processes (33) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (31) · Infections (28) · Inflammation (25)
Probiotics (7) · Spectroscopy, Near-Infrared (4) · Milk, Human (3) · Docosahexaenoic Acids (2) · Melatonin (2) · Metronidazole (2) · Pentoxifylline (2) · 4'-galactooligosaccharide (1) · Acetylcysteine (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Arginine (1) · Beds (1) · Cefazolin (1) · Chondroitin Sulfates (1) · Citric Acid (1)
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (5) · Per Torp Sangild (5) · University of Utah (5) · Ain Shams University (4) · Assiut University (3) · Shaare Zedek Medical Center (3) · Boston Children's Hospital (2) · Brigham and Women's Hospital (2) · Children's Mercy Hospital Kansas City (2) · Copenhagen University Hospital, Rigshospitalet (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Imperial College London (2) · Indiana University (2) · Infant Bacterial Therapeutics (2) · Rania Ali El-Farrash (2)
United States (43) · China (15) · United Kingdom (8) · Turkey (Türkiye) (7) · Canada (6) · France (6) · Israel (6) · Denmark (5) · Egypt (5) · Sweden (5) · Hong Kong (2) · Italy (2) · Mexico (2) · Poland (2) · South Africa (2)
Cathy Hammerman, MD (3) · Mariana Baserga, MD (3) · Christian C Yost, MD (2) · Jennifer Garcia, MD (2) · Josef Neu, MD (2) · Judy L Aschner, MD (2) · R. Lawrence Moss, MD (2) · Rania A El-Farrash, MD (2) · Aaron Hamvas, MD (1) · Agostino Pierro, OBE, MD (1) · Aleksandra M Cichonska, PhD (1) · Alev Esercan (1) · Almas Aamir, MSC (1) · Amelie Stritzke, MD (1) · Amy O'Connell, MD, PhD (1)
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K01DK075478 (1), K08HD052885 (1), P01HL086773 (1), R01HD093826 (1), R01HL138714 (1), R01NR010015 (1)