11 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 9 Not applicable, 4 Phase 2, 2 Early Phase 1, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 8, Active not recruiting 1 |
| Phase 2 | 4 | Completed 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Early Phase 1 | 2 | Completed 2 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow 4'-galactooligosaccharide: new trials by email Literature Review of 4'-galactooligosaccharide trials Research Report on 4'-galactooligosaccharide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of a Sugar Replacement on Blood Glucose Levels in Healthy Adults Galacto-Oligosaccharide, Glucose - Postprandial Hyperglycemia, Hyperinsulinemia | Not applicable | Active not recruiting | University of Aberdeen | 50 | 2025-01-17 | 2026-06-18 |
| Effect of Galacto-oligosaccharides (GOS) on Faecal Gut Microbiota in Adult Women GOS 1, GOS 2 - Microbial Colonization | Not applicable | Completed | Wageningen University and Research | 88 | 2023-05-12 | 2024-02-09 |
| At Home Placebo-controlled 8-week GOS Intervention on Emotion Behaviour and Cognition in Children (Age 6-14 Years). Galacto-oligosaccharide, Maltodextrin - Emotional Regulation | Not applicable | Completed | University of Surrey | 53 | 2021-02-01 | 2024-02-14 |
| Prebiotic Galacto-oligosaccharide and Acute GVHD Galacto-oligosaccharide, Maltodextrin - Acute GVHD | Phase 1 / Phase 2 | Recruiting | University of Kansas Medical Center | 128 | 2021-01-22 | 2026-04-22 |
| Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition Galacto-Oligosaccharide, Maltodextrin (Placebo) - Anxiety, Pain | Phase 2 | Withdrawn | Jeff Taekman, M.D. | 2017-06-09 | 2018-01-31 | |
| GOS and Insulin Sensitivity Galactooligosaccharide, maltodextrin - Obesity, Type 2 Diabetes Mellitus | Not applicable | Completed | Maastricht University Medical Center | 46 | 2014-10-01 | 2018-04-10 |
| Use of a Novel Synbiotic to Change Human Gut Bacteria and Improve Health in Obese Adults Bifidobacteria adolescentis BD1, Bifidobacteria animalis subsp. lactis BB-12, Bifidobacteria adolescentis BD1 and galactooligosaccharide - Intestinal Microbiota and Barrier Function | Not applicable | Completed | Rush University Medical Center | 151 | 2013-06-01 | 2021-11-23 |
| Effect of GOS Supplementation on Amoxicillin-treated Gut Microbiota From Healthy Adults GOS addition, Placebo - Colonic Diseases [C06.405.469.158] | Not applicable | Completed | Wageningen University | 12 | 2013-05-01 | 2013-11-20 |
| The Effect of Prebiotic B-GOS on the Immune Function, Metabolism and Gut Microbiota of Elderly People Bi2muno® GOS, Maltodextrin - Immunosenescence | Early Phase 1 | Completed | Clasado | 40 | 2011-05-01 | 2016-03-25 |
| Galactooligosaccharide, Immune Strength, and Digestive Health in Older Adults Over Cold and Flu Season Sucrose, Galactooligosaccharide - Healthy | Not applicable | Completed | University of Florida | 84 | 2010-10-01 | 2012-08-02 |
| Galactooligosaccharide, Immune Strength, and Digestive Health Sucrose, Galactooligosaccharide - Healthy | Not applicable | Completed | University of Florida | 427 | 2009-10-01 | 2012-08-02 |
| Efficacy of a Prebiotic Galactooligosaccharide to Reduce Metabolic Syndrome Risk Factors in Overweight Adults Bimuno, Maltodextrin - Metabolic Syndrome X | Phase 1 / Phase 2 | Completed | Clasado | 48 | 2009-10-01 | 2016-03-25 |
| Prebiotics in the Prevention of Necrotizing Enterocolitis Galacto-oligosaccharide (GOS), Placebo - Necrotizing Enterocolitis | Phase 2 | Unknown | Shaare Zedek Medical Center | 260 | 2009-07-01 | 2014-01-03 |
| Effect of Galactooligosaccharides on Incidence of Atopic Manifestations in Infants galactooligosaccharide - Atopic Dermatitis | Not applicable | Completed | Humana Co.Ltd. | 120 | 2009-06-01 | 2014-03-04 |
| Galactooligosaccharide (GOS) Supplementation and Calcium Absorption in Girls Galactooligosaccharide - Osteoporosis | Early Phase 1 | Completed | Purdue University | 31 | 2009-06-01 | 2018-05-09 |
Common Cold (2) · Influenza, Human (2) · Anxiety Disorders (1) · Communicable Diseases (1) · Dermatitis (1) · Dermatitis, Atopic (1) · Diabetes Mellitus, Type 2 (1) · Emotional Regulation (1) · Enterocolitis, Necrotizing (1) · Hyperglycemia (1) · Hyperinsulinism (1) · Insulin Resistance (1) · Metabolic Syndrome (1) · Obesity (1) · Osteoporosis (1)
Clasado (2) · University of Florida (2) · Humana Co.Ltd. (1) · Jeff Taekman, M.D. (1) · Maastricht University Medical Center (1) · Purdue University (1) · Rush University Medical Center (1) · Shaare Zedek Medical Center (1) · University of Aberdeen (1) · University of Kansas Medical Center (1) · University of Surrey (1) · Wageningen University (1) · Wageningen University and Research (1)
United States (6) · United Kingdom (4) · Netherlands (3) · Czechia (1) · Israel (1)
Bobbi Langkamp-Henken, PhD, RD (2) · Anthony Sung, MD (1) · Cathy Hammerman, MD (1) · Connie M Weaver, PhD (1) · Ellen E Blaak (1) · Glenn Gibson, PhD (1) · Jan Bozensky, MD (1) · Jeffrey M Taekman, M.D. (1) · Jelena Vulevic, PhD (1) · Jens Walter, PhD (1) · Karen Scott, PhD (1) · Maartje van den Belt, Msc (1) · Mitchell Horwitz, MD (1) · Robert Hutkins, PhD (1) · Stephanie Ladirat, MSc (1)
PMID 21525194, PMID 23303873, PMID 26571488, PMID 28396144, PMID 29954454, PMID 37189240, PMID 39224188, PMID 40025494
R01HL151365 (1)