5 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 9 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 5, Active not recruiting 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 2 | Unknown 1, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
Follow Muscle Atrophy: new trials by email Literature Review of Muscle Atrophy trials Research Report on Muscle Atrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Essential Amino Acid Supplementation for Femoral Fragility Fractures Essential Amino Acid Supplementation - Femoral Fracture, Fragility Fracture | Phase 2 | Recruiting | Michael C Willey | 60 | 2024-06-17 | 2026-10-07 |
| Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis. IMM01-STEM - Muscle Atrophy | Phase 1 / Phase 2 | Completed | Immunis, Inc. | 13 | 2022-09-13 | 2026-09-09 |
| Electrical Stimulation for Critically Ill Post-Covid-19 Patients Electrical Stimulation, Electrical Stimulation - Sham - COVID-19, Muscle Atrophy | Phase 2 | Completed | Baylor College of Medicine | 19 | 2021-08-18 | 2023-03-07 |
| Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS) Zoledronic Acid, Placebo - Bone Loss, Muscle Atrophy | Phase 2 | Completed | Stinus Gadegaard Hansen | 59 | 2021-02-20 | 2026-06-01 |
| Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection - Muscle Atrophy, Surgery | Phase 2 / Phase 3 | Unknown | The Stone Research Foundation for Sports Medicine and Arthritis | 15 | 2020-05-08 | 2021-08-31 |
| Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears Autologous Stomal Vascular Fraction Material, Ringer's solution - Rotator Cuff Tear, Muscle Atrophy | Phase 2 | Active not recruiting | Hospital for Special Surgery, New York | 56 | 2019-07-01 | 2026-09-03 |
| Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit beta-hydroxy-beta-methylbutyrate, Placebo, Vital HP® - Muscle Atrophy | Phase 2 / Phase 3 | Withdrawn | Massachusetts General Hospital | 2017-01-01 | 2021-05-05 | |
| Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults Essential Amino Acids (EAA), Placebo (Alanine) - Muscle Atrophy, Quality of Life | Phase 2 | Completed | University of Oregon | 80 | 2014-12-01 | 2024-07-23 |
| 5-Alpha Reductase and Anabolic Effects of Testosterone Testosterone Enanthate, Finasteride, Placebo - Male Hypogonadism, Muscle Atrophy | Phase 2 | Completed | VA Office of Research and Development | 60 | 2007-01-01 | 2018-10-11 |
Muscular Atrophy (9) · Bone Diseases, Metabolic (1) · COVID-19 (1) · Critical Illness (1) · Disease (1) · Eunuchism (1) · Femoral Fractures (1) · Knee Injuries (1) · Muscle Weakness (1) · Prostatic Hyperplasia (1) · Rotator Cuff Injuries (1) · Sarcopenia (1) · Wounds and Injuries (1)
Atrophy (9) · Nervous System Diseases (9) · Neurologic Manifestations (9) · Neuromuscular Manifestations (9) · Pathological Conditions, Anatomical (9) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Pathologic Processes (3) · Leg Injuries (2) · Musculoskeletal Diseases (2) · Wounds and Injuries (2) · Bone Diseases (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Disease Attributes (1)
Alanine (1) · Amino Acids, Essential (1) · Electric Stimulation (1) · Finasteride (1) · Histidine (1) · Injections, Intramuscular (1) · Isoleucine (1) · Leucine (1) · Methionine (1) · Phenylalanine (1) · Saline Solution (1) · Testosterone Propionate (1) · Threonine (1) · Tryptophan (1) · Valine (1)
Baylor College of Medicine (1) · Hospital for Special Surgery, New York (1) · Immunis, Inc. (1) · Massachusetts General Hospital (1) · Michael C Willey (1) · Stinus Gadegaard Hansen (1) · The Stone Research Foundation for Sports Medicine and Arthritis (1) · University of Oregon (1) · VA Office of Research and Development (1)
United States (7) · Denmark (1)
Mani Vessal, Ph.D. (1) · Michael C Willey, MD (1) · Sadeq A. Quraishi, MD,MHA,MMSc (1) · Scott Rodeo, MD (1) · Stephen Borst, PhD (1) · Tom Lane, PhD (1)
PMID 24012740, PMID 24326421, PMID 26733251, PMID 26829246, PMID 30280129, PMID 31343947, PMID 36209245, PMID 36905161, PMID 41177144
R01AG046401 (1)