619 completed, 246 unknown, 189 recruiting, 121 not yet recruiting. 744 Not applicable, 49 Phase 2, 24 Phase 3, 21 Phase 1, 20 Phase 4.
Follow Sarcopenia: new trials by email Literature Review of Sarcopenia trials Research Report on Sarcopenia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mixed Exercise Training and Novel Multi-Nutrient Supplementation in Young Adults Multi-nutrient supplement, Exercise - Sarcopenia | Not applicable | Withdrawn | McMaster University | 2030-01-20 | 2024-01-30 | |
| Sarcopenia in Chronic Kidney Disease (CKD) Patients Valine, EEA - Chronic Kidney Disease, Sarcopenia | Early Phase 1 | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 20 | 2027-07-01 | 2026-11-02 |
| The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck Nutrition counseling, Fresubin Supportan - Head &Amp;Amp; Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Anna Arthur, PhD | 15 | 2027-06-01 | 2026-08-07 |
| Evaluate the Efficacy and Safety of EN001 in Patients With Sarcopenia EN001, EN001 Placebo - Sarcopenia | Phase 1 / Phase 2 | Not yet recruiting | ENCell | 132 | 2027-03-01 | 2026-09-11 |
| Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES) - Critical Illness, Sarcopenia | Early Phase 1 | Not yet recruiting | University of Maryland, Baltimore | 78 | 2027-03-01 | 2026-05-06 |
| Exercise and Protein to Reduce Muscle Loss During GLP-1-Based Treatment in Type 2 Diabetes Supervised exercise training, protein supplement, Standardized lifestyle counseling - Type 2 Diabetes (T2DM), Obesity & Overweight | Not applicable | Not yet recruiting | German Diabetes Center | 94 | 2027-02-01 | 2026-11-09 |
| Strength and Dual-Task on Sarcopenia in People With Parkinson's Disease Nutricional Education and General Exercise Guidelines, Progressive Resistance Training With Cognitive Dual-Task Training, Progressive Resistance Training With Cognitive Dual-Task and Inestability Training - PARKINSON DISEASE (Disorder), Parkinsonism or Parkinson's Disease Nos | Not applicable | Recruiting | University of Valencia | 60 | 2027-01-11 | 2026-10-30 |
| The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM) D-STORM Resistance Training Programme, usual care - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Not applicable | Not yet recruiting | Universiti Teknologi Mara | 56 | 2027-01-01 | 2026-06-25 |
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| Yijinjing Exercise for Musculoskeletal Health in Adults With Sarcopenia Modified Yijinjing Exercise, Progressive Resistance Training, Dietary Counseling and Health Education - Sarcopenia | Not applicable | Not yet recruiting | Beijing Hospital of Traditional Chinese Medicine | 240 | 2027-01-01 | 2026-10-21 |
| MF-300 for Treatment of Age-Related Sarcopenia MF-300, Placebo - Sarcopenia in Elderly | Phase 2 | Not yet recruiting | Epirium Bio Inc. | 225 | 2027-01-01 | 2026-11-06 |
| Exercise and Nutritional Intervention in Patients With Melanoma Receiving Immunotherapy Structured Resistance Exercise, Individualized Nutritional Support - Melanoma | Not applicable | Not yet recruiting | Institute of Oncology Ljubljana | 40 | 2026-12-01 | 2026-10-07 |
| Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis Exercise training - Osteopenia, Osteoporosis | Not applicable | Withdrawn | University of Alabama at Birmingham | 2026-12-01 | 2026-07-01 | |
| HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide Calcium-HMB Plus Vitamin D3, Matching placebo - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Phase 2 | Not yet recruiting | Vanderbilt University Medical Center | 90 | 2026-12-01 | 2026-08-28 |
| Targeted Nutritional Intervention (HMB, Arginine, Glutamine) in Patients With Pancreatic Cancer HMB / L-Arginine / L-Glutamine oral nutritional mixture, Standard Dietary Counseling - PDAC, Pancreas Adenocarcinoma (MSI-H) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 24 | 2026-12-01 | 2026-10-20 |
| Eccentric Exercise in Community-dwelling Older Adults Eccentric exercise intervention - Ageing Well | Not applicable | Not yet recruiting | The University of Northampton | 30 | 2026-11-23 | 2026-11-04 |
| PROfiles of FGF-19 Post-prandial Secretion in Older Adults With Frailty and Without Frailty FLEXMEAL : post-prandial blood sampling - Frailty, Sarcopenia | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 30 | 2026-11-19 | 2026-11-10 |
| Comparison of Sarcopenia Index, Diaphragm Ultrasonography, and Traditional Weaning Parameters in Predicting Successful Weaning From Mechanical Ventilation sarcopenia index, diaphragma ultrasound, parameters of mechanical ventilation (MV) - Ventilator Weaning, Sarcopenia | Not yet recruiting | Kocaeli City Hospital | 80 | 2026-11-15 | 2026-09-28 | |
| The Aim of the Study is to Decipher the Alterations in Signalling Pathways of Skeletal Muscle Stem Cells (Satellite Cells (SCs)) in Individuals With COPD, as Well as to Examine the Effect of Exercise Training on SCs. Exercise training - COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia in Elderly | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 26 | 2026-11-15 | 2026-11-06 |
| Malnutrition and Sarcopenia in Adults With Chronic Kidney Disease in Tunisia Standardized nutritional and muscle assessment - Malnutrition, Sarcopenia | Not yet recruiting | Dacima Consulting | 4000 | 2026-11-15 | 2026-10-30 |
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Frailty (168) · Motor Activity (145) · Obesity (82) · Malnutrition (80) · Osteoporosis (63) · Muscular Atrophy (61) · Neoplasms (45) · Muscle Weakness (31) · Liver Cirrhosis (27) · Renal Insufficiency, Chronic (27) · Stroke (27) · Diabetes Mellitus (25) · Fibrosis (25) · Bone Diseases, Metabolic (24)
Pathological Conditions, Signs and Symptoms (1307) · Signs and Symptoms (1307) · Nervous System Diseases (1306) · Neurologic Manifestations (1306) · Neuromuscular Manifestations (1306) · Pathological Conditions, Anatomical (1306) · Atrophy (1297) · Muscular Atrophy (1246) · Pathologic Processes (328) · Nutritional and Metabolic Diseases (291) · Behavior (176) · Nutrition Disorders (176) · Musculoskeletal Diseases (152) · Metabolic Diseases (143) · Digestive System Diseases (120)
Exercise (79) · Resistance Training (69) · Absorptiometry, Photon (14) · Dietary Supplements (14) · Whey Proteins (14) · maltodextrin (13) · Hand Strength (12) · Proteins (12) · Creatine (11) · Nutritional Status (11) · Cholecalciferol (10) · Control Groups (10) · Vitamin D (10) · High-Intensity Interval Training (8) · Blood Specimen Collection (7)
National Taiwan University Hospital (22) · Maastricht University Medical Center (17) · Chang Gung Memorial Hospital (14) · University of Nottingham (14) · Bispebjerg Hospital (12) · University Hospital, Clermont-Ferrand (12) · The University of Texas Medical Branch, Galveston (10) · Istanbul Physical Medicine Rehabilitation Training and Research Hospital (9) · McMaster University (9) · Tufts University (9) · Ankara City Hospital Bilkent (8) · Ankara Etlik City Hospital (8) · Taipei Medical University (8) · University of Saskatchewan (8) · VA Office of Research and Development (8)
United States (187) · Turkey (Türkiye) (130) · Spain (96) · Taiwan (95) · China (76) · France (76) · United Kingdom (72) · Italy (69) · South Korea (40) · Canada (39) · Denmark (38) · Brazil (34) · Netherlands (32) · Belgium (30) · Germany (23)
Luc JC van Loon, PhD (7) · Bess Dawson-Hughes, MD (5) · Galip Can Uyar, MD (5) · Sang Yeoup Lee, MD, PhD (5) · Charlotte Suetta, Professor (4) · Elena Volpi, MD, PhD (4) · Bettina Mittendorfer, PhD (3) · Klaus Engelke, PhD (3) · Luc van Loon, PhD (3) · Paik Seong Lim, PhD (3) · Philip D Chilibeck, PhD (3) · Stuart M Phillips, PhD (3) · Stuart Phillips, Ph.D. (3) · Wolfgang Kemmler, PhD (3)
PMID 30312372, PMID 20392703, PMID 32069356, PMID 24737557, PMID 32033882, PMID 28095426, PMID 31081853, PMID 32941253, PMID 12028177, PMID 16030064, PMID 16614412, PMID 16896165, PMID 17351147, PMID 17912368, PMID 18323467, PMID 18342407, PMID 18713956, PMID 18787087, PMID 20876843, PMID 21093718, PMID 21448087, PMID 22018588, PMID 22338078, PMID 24374288, PMID 24737560, PMID 25243821, PMID 25475435, PMID 26882087, PMID 26922142, PMID 27077744, PMID 27507236, PMID 27935521, PMID 28473464, PMID 29349935, PMID 30513782, PMID 30587866, PMID 31171417, PMID 31547952, PMID 31722892, PMID 32230954, PMID 33249320, PMID 34121127, PMID 34708217, PMID 36070134, PMID 37752426, PMID 10728744, PMID 10749826, PMID 10872758, PMID 11074683, PMID 11328886
P30AG028740 (5), 2018 (2), P30AG028747 (2), 1IK2RD000462 (1), 2015 (1), 2017 (1), 2019 (1), 2025 (1), F31AT005384 (1), IK2RD000484-01A1 (1), K01HL148503 (1), K23DK099442 (1), M01RR000036 (1), P30AG021332 (1), P30AG021334 (1)