52 completed, 15 unknown, 9 terminated, 7 recruiting. 40 Not applicable, 16 Phase 2, 14 Phase 3, 11 Phase 4, 7 Phase 1.
Follow Migraine Headache: new trials by email Literature Review of Migraine Headache trials Research Report on Migraine Headache
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neuromodulation During the Prodrome to Prevent Disabling Migraine Attacks in Youth Active Remote Electrical Neuromodulation, Sham Remote Electrical Neuromodulation - Migraine, Migraine Headache | Not applicable | Not yet recruiting | University of Calgary | 30 | 2026-10-01 | 2026-08-19 |
| Behavioral Resources and Awareness for Veterans With Episodic Migraine: Impact on Neurological Disability and Quality of Life- Pilot Cognitive behavioral therapy for migraine (CBTm), MEintervention - Migraine, Migraine Headache | Not applicable | Not yet recruiting | Yale University | 24 | 2026-10-01 | 2026-08-31 |
| Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START Study Foundational dietary supplement, Luteal phase dietary supplement add-on, Migraine phase dietary supplement add-on - Migraine, Migraine Disease | Not applicable | Not yet recruiting | Miracle Wellness LLC | 920 | 2026-07-08 | 2026-06-08 |
| A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department Rimegepant, Zavegepant - Migraine, Migraine Disease | Phase 1 | Not yet recruiting | University of South Florida | 100 | 2026-07-01 | 2026-06-25 |
| Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD Intervention yoga based exercises - Cluster Headache - Episodic and Chronic, Migraine Headache | Not applicable | Recruiting | Karolinska Institutet | 80 | 2026-05-01 | 2026-09-23 |
| Light Exposure, Migraine Outcomes, and Sleep Quality Ambient Lighting Condition - Migraine Headache, Sleep | Not applicable | Recruiting | Arizona State University | 20 | 2026-03-24 | 2026-04-28 |
| Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study Intervention yogabased movements - Cluster Headache - Episodic and Chronic, Migraine Headache | Not applicable | Active not recruiting | Karolinska Institutet | 20 | 2026-01-01 | 2026-09-23 |
| Assessment of the Impact of Headache on the Employee Population of Libbs Pharmaceutical Ltd Migraine Headache, Migraine | Enrolling by invitation | Libbs Farmacêutica LTDA | 1342 | 2026-01-01 | 2025-12-19 | |
| The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine Standard acupuncture, Electroacupuncture, Laser Acupuncture - Migraine, Migraine Headache | Not applicable | Active not recruiting | University Medical Centre Ljubljana | 75 | 2025-11-03 | 2025-12-18 |
| Evaluation of a Wearable Device for Acute Treatment of Migraines Transcutaneous Electrical Nerve Stimulation (TENS) - Migraine, Migraine With or Without Aura | Not applicable | Completed | Hinge Health, Inc | 160 | 2025-06-09 | 2025-10-30 |
| Neuro-Complex & Multi Supplements for Migraine Prevention Neuro-Complex and Multi - Migraine Headache, Migraine | Not applicable | Recruiting | Benfida, a department of Handi-Move | 120 | 2025-05-15 | 2025-06-11 |
| Cooling to Alleviate Migraine #3 Mi-Helper - Migraine With or Without Aura, Migraine | Not applicable | Completed | Mi-Helper, Inc. | 156 | 2025-03-24 | 2026-02-10 |
| Autonomic Dysfunction in Patients With Migraine: Cardiovascular and Neurophysiology Assessment Migraine Headache | Active not recruiting | Beni-Suef University | 116 | 2025-01-07 | 2025-01-29 | |
| Long-term Atogepant in Real-world Practice Atogepant 60 mg, Headache diary, Patient-reported outcome measures - Migraine, Headache | Completed | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | 513 | 2024-06-01 | 2026-09-23 | |
| Vitamin K2 Supplementation in Adult Episodic Migraine Vitamin K2 or menaquinone-7, Placebo - Migraine Headache, Arterial Stiffness | Not applicable | Recruiting | Sola Aoun Bahous, M.D. Ph.D. | 160 | 2024-03-06 | 2025-11-18 |
| A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine Biodegradable occluder, Metal occluder - PFO - Patent Foramen Ovale, Migraine | Not applicable | Recruiting | Chinese Academy of Medical Sciences, Fuwai Hospital | 400 | 2024-03-01 | 2025-12-04 |
| Migraine Attack Pain Phase Prediction Study Migraine, Migraine Headache | Active not recruiting | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | 70 | 2023-10-09 | 2026-09-23 | |
| Oxygen in Migraine Treatment oxygen - Migraine Headache, Oxygen | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 160 | 2023-06-01 | 2025-04-11 | |
| Migraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervention Would Be Beneficial (MANET) blood samples collection - Migraine Headache, PFO - Patent Foramen Ovale | Unknown | Centro Cardiologico Monzino | 120 | 2023-05-18 | 2024-02-08 | |
| Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs) - Migraine, Migraine Disease | Phase 4 | Recruiting | Ain Shams University | 120 | 2023-04-26 | 2025-06-15 |
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Migraine Disorders (94) · Headache (25) · Migraine without Aura (6) · Migraine with Aura (5) · Bronchiolitis Obliterans Syndrome (3) · Pain (3) · Cluster Headache (2) · Epilepsy (2) · Foramen Ovale, Patent (2) · Headache Disorders (2) · Tension-Type Headache (2) · Chronic Pain (1) · Cognitive Dysfunction (1) · Fasting (1) · Headache Disorders, Primary (1)
Brain Diseases (94) · Central Nervous System Diseases (94) · Nervous System Diseases (94) · Headache Disorders, Primary (93) · Headache Disorders (92) · Pathological Conditions, Signs and Symptoms (27) · Neurologic Manifestations (26) · Signs and Symptoms (26) · Pain (22) · Behavior (3) · Bronchial Diseases (3) · Bronchiolitis (3) · Bronchiolitis Obliterans (3) · Bronchitis (3) · Graft vs Host Disease (3)
Sumatriptan (5) · rizatriptan (5) · Propofol (3) · Saline Solution (3) · Anti-Inflammatory Agents, Non-Steroidal (2) · Caffeine (2) · Celecoxib (2) · Dihydroergotamine (2) · Ketorolac Tromethamine (2) · Lidocaine (2) · Metoclopramide (2) · Propranolol (2) · Psilocybin (2) · Tryptamines (2) · erenumab (2)
Eli Lilly and Company (4) · Organon and Co (4) · Yale University (3) · Ain Shams University (2) · Alexza Pharmaceuticals, Inc. (2) · BioDelivery Sciences International (2) · Fundación de Investigación Biomédica - Hospital Universitario de La Princesa (2) · Impel Pharmaceuticals (2) · Karolinska Institutet (2) · Shiraz University of Medical Sciences (2) · The Cleveland Clinic (2) · Ache Laboratorios Farmaceuticos S.A. (1) · Albert Einstein Healthcare Network (1) · Amgen (1) · Ankara Ataturk Sanatorium Training and Research Hospital (1)
United States (54) · Canada (6) · Spain (4) · Australia (3) · Egypt (3) · Finland (3) · Iran (3) · Italy (3) · United Kingdom (3) · Brazil (2) · Hungary (2) · Poland (2) · Sweden (2) · Turkey (Türkiye) (2) · Austria (1)
Ana Beatriz Gago Veiga (2) · Abdolhamid Shariat, MD, Assistant Professor (1) · Alex Rosin, MD (1) · Alexandra Hovaguimian, MD (1) · Anna Huguet, PhD (1) · Arthur Elkind, MD (1) · Ayat F Mohamed (1) · Caren Behar, MD (1) · Christopher Jones, MD (1) · Daniel A Spyker, PhD, MD (1) · Daniel Laskowitz, MD (1)
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1UG3AT013498-01 (1), 2018 (1), 2019 (1), UL1TR000135 (1)