28 completed, 1 recruiting, 1 withdrawn. 20 Phase 3, 6 Phase 4, 2 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Completed 20 |
| Phase 4 | 6 | Completed 5, Recruiting 1 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow rizatriptan: new trials by email Literature Review of rizatriptan trials Research Report on rizatriptan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache Rimegepant, Rizatriptan Benzoate - Migraine | Phase 4 | Recruiting | Antonios Likourezos | 80 | 2024-09-01 | 2026-09-24 |
| Efficacy and Safety of Rizatriptan-Naproxen (10/550 mg) in the Acute Treatment of Migraine Rizatriptan 10 mg + Naproxen 550mg, Maxalt 10Mg Tablet, Flanax 550mg - Migraine | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 2068 | 2022-12-30 | 2026-10-26 |
| Initiating Early Control of Migraine Pain and Associated Symptoms AXS-07 (MoSEIC meloxicam and rizatriptan), Placebo - Migraine | Phase 3 | Completed | Axsome Therapeutics, Inc. | 302 | 2019-10-08 | 2026-01-28 |
| Maximizing Outcomes in Treating Acute Migraine AXS-07 (MoSEIC meloxicam and rizatriptan), Meloxicam, Rizatriptan - Migraine | Phase 3 | Completed | Axsome Therapeutics, Inc. | 1594 | 2019-03-04 | 2023-08-24 |
| Rizatriptan for Episodic Dizziness in Vestibular Migraine Rizatriptan, Placebo - Vestibular Migraine, Migrainous Vertigo | Phase 2 / Phase 3 | Completed | Robert W. Baloh | 223 | 2014-12-01 | 2021-11-04 |
| Study of Rizatriptan in the Treatment of Acute Attacks of Post-traumatic Headache in U.S. Military Troops Rizatriptan, Placebo - Chronic Post-traumatic Headache | Not applicable | Withdrawn | Henry M. Jackson Foundation for the Advancement of Military Medicine | 2011-02-01 | 2015-08-18 | |
| A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents (MK-0462-086 AM3) rizatriptan benzoate - Acute Migraine With or Without Aura in Adolescents | Phase 3 | Completed | Organon and Co | 674 | 2009-12-01 | 2024-04-22 |
| A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine in Children and Adolescents (MK-0462-082 AM7) rizatriptan, placebo - Migraine, Acute | Phase 3 | Completed | Organon and Co | 1382 | 2009-11-30 | 2024-05-07 |
| Rizatriptan in Acute Treatment of Migraine in Patients With Unilateral Trigeminal-autonomic Symptoms. rizatriptan or placebo - Migraine | Phase 4 | Completed | IRCCS San Raffaele | 80 | 2009-07-01 | 2011-10-12 |
| A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine (0462-087) rizatriptan, Comparator: Placebo, Comparator: Sumatriptan - Acute Migraine | Phase 3 | Completed | Organon and Co | 109 | 2009-06-10 | 2024-05-10 |
| A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine Prophylaxis rizatriptan benzoate, Comparator: placebo - Migraine | Phase 3 | Completed | Organon and Co | 108 | 2009-03-24 | 2024-05-23 |
| The Effects of Expectation and Knowledge on Rizatriptan and Placebo Treatment of Acute Migraine Headache Maxalt, placebo pill, placebo pills - Episodic Migraine | Phase 4 | Completed | Beth Israel Deaconess Medical Center | 76 | 2008-09-01 | 2015-04-09 |
| Rizatriptan 10 MG RPD in the Treatment of Acute Migraine Rizatriptan - Migraine | Phase 4 | Completed | Universität Duisburg-Essen | 195 | 2008-05-01 | 2013-01-28 |
| Drug Study in Pediatric Subjects With Migraines (MK0462-083 AM1) rizatriptan benzoate (5 mg), rizatriptan benzoate (10 mg), Rizatriptan 5 mg Placebo - Migraine Disorders | Phase 1 | Completed | Organon and Co | 31 | 2007-12-17 | 2024-04-19 |
| Study to Test Rizatriptan in the Early Treatment of Acute Migraine (0462-081) Comparator: rizatriptan benzoate, Comparator: Placebo - Migraine | Phase 3 | Completed | Organon and Co | 207 | 2007-10-03 | 2024-04-22 |
| Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache Maxalt 10mg MLT plus Caffeine 75mg, Maxalt 10mg MLT plus Placebo, Placebo + Placebo - Migraine With Aura, Migraine Without Aura | Phase 3 | Completed | Diamond Headache Clinic | 50 | 2007-04-01 | 2012-04-25 |
| Telcagepant (MK-0974) Long-Term Safety Study in Adult Participants With Acute Migraine (MK-0974-012) Telcagepant 300 mg soft gel capsules, Telcagepant 280 mg tablets, Rizatriptan 10 mg tablets - Migraine | Phase 3 | Completed | Merck Sharp & Dohme LLC | 1068 | 2007-02-21 | 2018-10-17 |
| Two Rizatriptan Prescribing Portions for Treatment of Migraine rizatriptan - Migraine | Phase 4 | Completed | Clinvest | 197 | 2006-12-01 | 2010-06-08 |
| Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines? Rizatriptan, Placebo - Migraine | Not applicable | Completed | University of Pittsburgh | 36 | 2006-08-01 | 2014-12-08 |
| A Dose-Finding Study of MK0974 in Acute Migraine (MK0974-004) Comparator: Placebo, MK0974, Rizatriptan - Migraine | Phase 2 | Completed | Merck Sharp & Dohme LLC | 420 | 2005-11-01 | 2015-11-02 |
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Migraine Disorders (25) · Headache (2) · Migraine with Aura (1) · Migraine without Aura (1) · Motion Sickness (1)
Organon and Co (15) · Axsome Therapeutics, Inc. (2) · Merck Sharp & Dohme LLC (2) · Antonios Likourezos (1) · Beth Israel Deaconess Medical Center (1) · Clinvest (1) · Diamond Headache Clinic (1) · Eurofarma Laboratorios S.A. (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · IRCCS San Raffaele (1) · Ohio University (1) · Robert W. Baloh (1) · University of Pittsburgh (1) · Universität Duisburg-Essen (1)
United States (10) · Brazil (1) · Germany (1) · Italy (1)
Frederick G Freitag, DO (1) · Hans-Christoph Diener, Prof. (1) · Jay C Erickson, MD (1) · Joseph M Furman, MD, PhD (1) · Kenneth A Holroyd, Ph.D. (1) · Piero Barbanti, MD, PhD (1) · Rami Burstein, PhD (1) · Robert W Baloh, M.D. (1) · Roger K Cady, MD (1) · Sergey Motov, MD (1)
PMID 11284464, PMID 11284463, PMID 11422095, PMID 19817885, PMID 20862509, PMID 20880898, PMID 21070230, PMID 21078681, PMID 22078129, PMID 22289113, PMID 22460943, PMID 22711898, PMID 23078588, PMID 24401940, PMID 37042545, PMID 40354049, PMID 9595867, PMID 9748025