Migraine: Clinical Trials

906 trials for Migraine, newest first

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532 completed, 111 unknown, 89 recruiting, 49 not yet recruiting. 322 Not applicable, 142 Phase 3, 98 Phase 4, 88 Phase 2, 58 Phase 1.

By phase and status

PhaseTrialsStatus
Not applicable322Completed 176, Unknown 45, Recruiting 34, Not yet recruiting 21, Terminated 17, Active not recruiting 10, Withdrawn 10, Enrolling by invitation 7, Suspended 2
Phase 3142Completed 106, Unknown 8, Recruiting 7, Terminated 6, Withdrawn 6, Active not recruiting 4, Enrolling by invitation 2, Not yet recruiting 2, Suspended 1
Phase 498Completed 66, Unknown 11, Recruiting 7, Withdrawn 4, Active not recruiting 3, Not yet recruiting 3, Terminated 3, Enrolling by invitation 1
Phase 288Completed 56, Terminated 10, Recruiting 7, Unknown 6, Withdrawn 5, Not yet recruiting 2, Enrolling by invitation 1, Suspended 1
Phase 158Completed 45, Unknown 5, Terminated 4, Enrolling by invitation 2, Not yet recruiting 1, Withdrawn 1
Early Phase 14Recruiting 2, Completed 1, Unknown 1

Follow this condition Literature Review of Migraine trials Research Report on Migraine

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Observational Study to Assess Migraine Prediction Tool
Daily questionnaire - Migraine
SuspendedTheranica2002030-01-012024-11-22
Nortriptyline Compared With Amitriptyline for Migraine Prevention at SQUH
Nortriptyline, Amitriptyline - Migraine
Phase 4Not yet recruitingSultan Qaboos University902027-05-012026-10-02
Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial
Migraine Behavioral Treatment - Migraine, Headache
Not applicableNot yet recruitingMayo Clinic242026-12-012026-06-16
Assessment of Head Awareness in Patients With Migraine in the Greek Population
Migraine
Not yet recruitingNational and Kapodistrian University of Athens902026-11-012026-10-08
Validity and Reliability of the Greek WPAI:Migraine
Migraine
Not yet recruitingNational and Kapodistrian University of Athens602026-11-012026-10-08
Validity and Reliability of the Greek Pain Catastrophizing Scale
Migraine
Not yet recruitingNational and Kapodistrian University of Athens1302026-11-012026-10-07
Headache and Hormone Use Among Transgender Population in Thailand: A Cross-Sectional Online Study
gender-affirming hormone therapy, Gender-Affirming Surgery, HIV Pre-Exposure Prophylaxis - Headache, Migraine
Not yet recruitingChulalongkorn University5002026-11-012026-09-14
A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Elismetrep, Placebo - Migraine
Phase 3RecruitingKallyope Inc.15002026-10-022026-10-14
Neuromodulation During the Prodrome to Prevent Disabling Migraine Attacks in Youth
Active Remote Electrical Neuromodulation, Sham Remote Electrical Neuromodulation - Migraine, Migraine Headache
Not applicableNot yet recruitingUniversity of Calgary302026-10-012026-08-19
Migraine Characteristics and Associated Factors
Observational assessment - Migraine
Not yet recruitingLokman Hekim University1002026-10-012026-09-16
Behavioral Resources and Awareness for Veterans With Episodic Migraine: Impact on Neurological Disability and Quality of Life- Pilot
Cognitive behavioral therapy for migraine (CBTm), MEintervention - Migraine, Migraine Headache
Not applicableNot yet recruitingYale University242026-10-012026-08-31
Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain
BREATHE with Headache (BREATHE-HA), Enhanced Standard-of-Care: Headache Education - Migraine, Migraine in Adolescence
Not applicableNot yet recruitingUniversity of Colorado, Denver722026-10-012026-08-10
Tear Biomarkers for Migraine
Patients with migraine - Migraine
Not yet recruitingFondazione Policlinico Universitario Agostino Gemelli IRCCS4002026-09-302026-07-10
A Prospective Interventional Study of Intranasal Zavegepant for the Acute Treatment of Migraine
Patient Headache Diary, Patient Reported Outcome, intranasal zavegepant - Migraine
Not applicableNot yet recruitingAmerican Center for Psychiatry and Neurology2502026-09-302026-10-06
Biological Profiles of Neuropeptides, Neurotrophins and miRNA in Migraine
Rimegepant 75 MG - Migraine
Not yet recruitingNordlandssykehuset HF602026-09-172026-09-21
Investigation of Imagery Abilities in Individuals With Migraine
Migraine, Healthy Participants
Not yet recruitingHacettepe University1262026-09-162026-09-28
Study to Assess Effectiveness of Oral Atogepant in Adult Participants For Prevention of Migraine in the United Kingdom
Migraine
Not yet recruitingAbbVie2002026-09-012026-07-08
Vibratory Stimulation for the Treatment of Chronic Pain
Vibrotactile Stimulation, Sham Stimulation - Chronic Pain, Pelvic Pain
Not applicableSuspendedStanford University502026-09-012026-04-24
Visual Instillation of Sphenopalatine-block Intervention for ONgoing Migraine
Topical solution of 4% lidocaine, Saline 0.9% - Migraine, Facial Pain or Pressure
Phase 2Not yet recruitingAssociation of Migraine Disorders742026-09-012026-08-14
EMBRACE-OBS: Single-Site Observational Registry of Patient-Reported Outcomes Following MMA Embolization for Migraine
Middle Meningeal Artery Embolization - Migraine Disorders, Chronic Migraine Headache
RecruitingCortex Neurovascular502026-09-012026-09-23

Showing 20 of 906. Sign in to see all of them.

Narrower conditions

Migraine Disorders (906)  ·  Headache (198)  ·  Pain (56)  ·  Migraine with Aura (43)  ·  Migraine without Aura (37)  ·  Headache Disorders (25)  ·  Tension-Type Headache (25)  ·  Epilepsy (19)  ·  Headache Disorders, Primary (14)  ·  Depression (13)  ·  Motor Activity (13)  ·  Foramen Ovale, Patent (12)  ·  Photophobia (12)  ·  Headache Disorders, Secondary (11)  ·  Multiple Sclerosis (11)

Broader conditions

Central Nervous System Diseases (903)  ·  Nervous System Diseases (903)  ·  Brain Diseases (902)  ·  Headache Disorders, Primary (892)  ·  Headache Disorders (881)  ·  Pathological Conditions, Signs and Symptoms (289)  ·  Signs and Symptoms (274)  ·  Neurologic Manifestations (265)  ·  Pain (191)  ·  Behavior (40)  ·  Cardiovascular Diseases (31)  ·  Mental Disorders (29)  ·  Pathologic Processes (29)  ·  Immune System Diseases (28)  ·  Otorhinolaryngologic Diseases (23)

Interventions

erenumab (42)  ·  Topiramate (39)  ·  rimegepant sulfate (29)  ·  Sumatriptan (28)  ·  eptinezumab (19)  ·  fremanezumab (18)  ·  galcanezumab (16)  ·  rizatriptan (16)  ·  Sodium Chloride (14)  ·  Amitriptyline (12)  ·  Naproxen (12)  ·  lasmiditan (12)  ·  Acupuncture Therapy (11)  ·  ubrogepant (11)  ·  Lidocaine (10)

Sponsors

Danish Headache Center (36)  ·  Pfizer (28)  ·  Eli Lilly and Company (20)  ·  Amgen (18)  ·  AbbVie (17)  ·  H. Lundbeck A/S (15)  ·  Theranica (15)  ·  Merck Sharp & Dohme LLC (14)  ·  Thomas Jefferson University (14)  ·  Mayo Clinic (12)  ·  Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (11)  ·  Montefiore Medical Center (11)  ·  IRCCS National Neurological Institute "C. Mondino" Foundation (10)  ·  NYU Langone Health (10)  ·  Cefaly Technology (7)

Countries

United States (361)  ·  Italy (68)  ·  Spain (58)  ·  Denmark (55)  ·  Germany (53)  ·  Turkey (Türkiye) (51)  ·  Canada (47)  ·  China (42)  ·  France (38)  ·  United Kingdom (35)  ·  Poland (30)  ·  Belgium (29)  ·  Japan (28)  ·  Israel (26)  ·  Czechia (18)

Top investigators

Roger K Cady, MD (6)  ·  Cristina Tassorelli, Prof (5)  ·  Mia Minen, MD (5)  ·  Alit Stark Inbar, PhD (4)  ·  Alit Stark-Inbar, PhD (4)

Results publications

PMID 11914403, PMID 12807523, PMID 31482569, PMID 31952501, PMID 32576229, PMID 34264500, PMID 34928306, PMID 35076090, PMID 37303034, PMID 8984084, PMID 19486178, PMID 30462830, PMID 30594122, PMID 30942898, PMID 31253091, PMID 33069214, PMID 33143451, PMID 33413075, PMID 33544305, PMID 33549036, PMID 33950375, PMID 34049484, PMID 34819017, PMID 35139816, PMID 35331009, PMID 35471625, PMID 35779194, PMID 35978286, PMID 35979677, PMID 36038833, PMID 37965170, PMID 38581615, PMID 39221611, PMID 39982105, PMID 40275185, PMID 41235617, PMID 42129417, PMID 10221784, PMID 10449117, PMID 10778892, PMID 10946944, PMID 11167908, PMID 14728706, PMID 14982912, PMID 15096395, PMID 15316798, PMID 15622223, PMID 15724736, PMID 15870415, PMID 16183246

NIH funding

2019 (14), 2023 (9), 2015 (5), 2018 (4), 2008 (2), 2014 (2), 2025 (2), K01NS124911 (2), R01AT011005 (2), 1UG3AT013498-01 (1), 2005 (1), 2016 (1), K23AT008406 (1), K23AT009706 (1), K23AT013838 (1)