15 completed, 5 unknown, 3 recruiting. 10 Not applicable, 6 Phase 4, 3 Phase 3, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 7, Recruiting 2, Unknown 1 |
| Phase 4 | 6 | Completed 5, Unknown 1 |
| Phase 3 | 3 | Unknown 2, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Midazolam: new trials by email Literature Review of Midazolam trials Research Report on Midazolam
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery Virtual Reality Group, Midazolam Group - Anxiolytic Effect, Virtual Reality Immersion | Not applicable | Recruiting | Cairo University | 40 | 2025-06-01 | 2025-07-03 |
| Nebulized Dexmedetomidine, Ketamine, or Midazolam in Children Undergoing Adenotonsillectomy Group K:nebulized ketamine group, Group D:dexmedetomidine group, Group M: midazolam group - Dexmedetomidine, Adenotonsillectomy | Not applicable | Completed | Tanta University | 60 | 2024-11-30 | 2026-05-07 |
| Sedation With Dexmedetomidine or Midazolam in Combination With Propofol for Removal of Double-J Ureteral Stent Propofol, Propofol and Dexmedetomidine, Propofol and Midazolam - Sedation, Dexmedetomidine | Not applicable | Completed | Tanta University | 60 | 2024-11-01 | 2026-05-12 |
| Nebulized Ketamine for the Treatment of Major Depressive Disorder nebulized ketamine, nebulized midazolam - Severe Depression, Moderate Depression | Phase 3 | Recruiting | Theresa Jacob, PhD, MPH | 40 | 2024-10-16 | 2026-04-24 |
| Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer Midazolam oral solution, Placebo - Preoperative, Sleep Disturbance | Not applicable | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 280 | 2024-07-24 | 2025-04-06 |
| Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Byfavo, Midazolam - Midazolam, Remimazolam | Phase 2 | Unknown | Yeungnam University Hospital | 330 | 2024-03-01 | 2024-02-23 |
| ED50 of Midazolam Oral Solution for Preoperative Hypnosis in Adults : An Up-and-Down Sequential Allocation Trial Midazolam oral solution - Dose, Midazolam | Not applicable | Completed | Sixth Affiliated Hospital, Sun Yat-sen University | 22 | 2023-09-05 | 2025-08-06 |
| A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam ZSP1273 - Drug Drug Interaction, Warfarin | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 28 | 2023-06-25 | 2023-12-06 |
| Preoperative Anxiolysis With Intravenous Midazolam on Intraoperative Sevoflurane Gas Consumption Midazolam, Saline - Midazolam, Sevoflurane | Phase 4 | Completed | Cukurova University | 80 | 2022-12-02 | 2024-05-01 |
| Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs. Dexmedetomidine, Midazolam - Dexmedetomidine, Midazolam | Phase 3 | Unknown | King Abdullah International Medical Research Center | 430 | 2022-04-21 | 2023-04-27 |
| Intranasal Dexmedetomidine Versus Oral Midazolam as Premedication for Propofol Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging Dexmedetomidine, Midazolam - MRI, Pediatric Sedation | Phase 3 | Unknown | Brugmann University Hospital | 250 | 2022-03-09 | 2022-03-24 |
| Midazolam Efficacy/Safety in Pre-Eclamptic C-Section Sedation 0 mg/kg Midazolam (Control Group), 0.01 mg/kg Midazolam Group, 0.02 mg/kg Midazolam Group - Midazolam, Pre-eclampsia | Not applicable | Completed | Zhuji People's Hospital of Zhejiang Province | 124 | 2021-04-05 | 2025-06-15 |
| Remimazolam Tosilate Sedation and Midazolam Sedation in Dental Patients Fentanyl, Flurbiprofen, Midazolam - Sedation Complication, Midazolam | Phase 4 | Completed | Peking University | 81 | 2021-04-01 | 2022-03-15 |
| Comparison Between Remimazolam Tosilate and Midazolam in Elderly Patients Undergoing Gastrointestinal Endoscopy remimazolam tosilate group, Midazolam group - Elderly Patients, Gastrointestinal Endoscopy | Not applicable | Completed | Peking University People's Hospital | 353 | 2021-04-01 | 2023-06-22 |
| Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea Drug-induced sleep endoscopy, Natural sleep endoscopy - Sleep Apnea, Obstructive, Sleep Apnea | Not applicable | Unknown | ethisch.comite@uza.be | 40 | 2021-03-30 | 2021-07-26 |
| Intranasal Dexmedetomidine Versus Intranasal Midazolam for MRI In Pediatrics Dexmedetomidine, Midazolam - Dexmedetomidine, Midazolam | Phase 4 | Completed | Tanta University | 60 | 2020-12-10 | 2023-04-20 |
| The Effects of Mild Sedation on Motor Function Networks in Patients With Brian Gliomas Midazolam, Dexmedetomidine - Brain Glioma, Midazolam | Not applicable | Completed | Beijing Tiantan Hospital | 38 | 2020-11-25 | 2025-06-03 |
| The Use of Midazolam as Adjuvant to Bupivacaine Intrathecal Anesthesia for Children Undergoing Lower Abdominal Surgeries. intrathecal bupivacaine, midazolam - Analgesia, Children, Only | Early Phase 1 | Completed | Tanta University | 120 | 2020-01-18 | 2021-03-22 |
| Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years Meperidine, Hydroxyzine, Midazolam - Dental Caries in Children, Pediatric Dental Sedation | Phase 4 | Completed | University of Washington | 37 | 2019-06-25 | 2024-01-24 |
| Midazolam Additive to Local Anesthetic in Peribulbar Block Peribulbar block (control), Peribulbar block(M1), Peribulbar block(M2) - Postoperative Pain, Cataract | Not applicable | Completed | Al Jedaani Hospital | 90 | 2018-01-01 | 2018-08-14 |
Showing 20 of 23. Sign in to see all of them.
Anxiety Disorders (2) · Pain, Postoperative (2) · Agnosia (1) · Apnea (1) · Cataract (1) · Colorectal Neoplasms (1) · Depression (1) · Dyssomnias (1) · Nervous System Diseases (1) · Parasomnias (1) · Pre-Eclampsia (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Sleep Apnea Syndromes (1) · Sleep Apnea, Obstructive (1)
Mental Disorders (4) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Nervous System Diseases (2) · Pain (2) · Pathologic Processes (2) · Postoperative Complications (2) · Behavior (1) · Behavioral Symptoms (1) · Chemically-Induced Disorders (1) · Colonic Diseases (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Eye Diseases (1)
Midazolam (19) · Dexmedetomidine (7) · Fentanyl (2) · remimazolam (2) · Calorimetry (1) · Calorimetry, Indirect (1) · Control Groups (1) · Flurbiprofen (1) · Hydroxyzine (1) · Ketamine (1) · Meperidine (1) · Propofol (1) · Sodium Chloride (1) · ZSP1273 (1)
Tanta University (4) · Cairo University (2) · Sixth Affiliated Hospital, Sun Yat-sen University (2) · Al Jedaani Hospital (1) · Beijing Tiantan Hospital (1) · Brugmann University Hospital (1) · Centre Hospitalier Universitaire, Amiens (1) · Cukurova University (1) · Guangdong Raynovent Biotech Co., Ltd (1) · Hospital Sao Domingos (1) · King Abdullah International Medical Research Center (1) · Peking University (1) · Peking University People's Hospital (1) · Theresa Jacob, PhD, MPH (1) · University of Washington (1)
China (7) · Egypt (5) · Saudi Arabia (3) · Belgium (2) · United States (2) · Brazil (1) · South Korea (1) · Turkey (Türkiye) (1)
Ersel Gulec, MD (1) · Mohamed Abdulatif, Professor (1) · Olivier Vanderveken, MD, PhD (1) · Theresa Jacob, PhD, MPH (1) · Travis M Nelson, DDS (1) · Xudong Yang, MD (1)
PMID 30627737, PMID 34950101, PMID 37568242, PMID 38760702, PMID 42683653