105 unknown, 71 recruiting, 57 completed, 43 not yet recruiting. 103 Not applicable, 52 Phase 2, 40 Phase 3, 12 Phase 4, 4 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-PCSK9 Antibody Tafolecimab and Anti-PD-1 Antibody Sintilimab Combined With Neoadjuvant Chemoradiotherapy for pMMR/ MSS Locally Advanced Rectal Cancer : A Prospective, Multicenter, Randomized, Open-Label, Parallel-Controlled Trial Short-course radiotherapy, CAPOX (oxaliplatin/capecitabine), Sintilimab - Local Advanced Rectal Cancer, PD-1 Inhibitor | Phase 3 | Not yet recruiting | Guangdong Provincial People's Hospital | 148 | 2027-01-01 | 2026-07-07 |
| Longitudinal Registry of Difficult-to-Treat Inflammatory Bowel Disease Routine IBD Management and Advanced-Therapy Exposure - Inflammatory Bowel Diseases (IBD), Crohn Disease | Not yet recruiting | First Affiliated Hospital, Sun Yat-Sen University | 2000 | 2026-11-01 | 2026-10-16 | |
| Objective Disease Control and Treatment Strategies in Ulcerative Colitis Routine Clinical Care - Ulcerative Colitis (Disorder) | Not yet recruiting | First Affiliated Hospital, Sun Yat-Sen University | 1000 | 2026-11-01 | 2026-10-16 | |
| Immune Aging and Advanced Therapy Outcomes in Older Adults With IBD Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Frailty | Not yet recruiting | First Affiliated Hospital, Sun Yat-Sen University | 300 | 2026-10-12 | 2026-10-13 | |
| mFOLFOXIRI Plus Bevacizumab for Organ Preservation in Locally Advanced Rectal Cancer FOLFOXIRI + Bevacizumab - Phase 2 Study | Phase 2 | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 119 | 2026-09-30 | 2026-09-14 |
| Node-Sparing Short-Course Radiotherapy (25 Gy/5 Fractions) Combined With Chemoimmunotherapy as Neoadjuvant Treatment for Locally Advanced Esophageal Squamous Cell Carcinoma：A Prospective Single-Arm, Phase II Study Neoadjuvant SCRT + Camrelizumab + Nab-Paclitaxel/Carboplatin - ESCC | Phase 2 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 33 | 2026-09-10 | 2026-09-09 |
| NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC Short-Course Radiotherapy, PD-1 monoclonal antibody, mFOLFOX6 regimen - Rectal Adenocarcinoma, High-Risk Cancer | Phase 2 | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 100 | 2026-09-01 | 2026-08-14 |
| Preoperative Home-based Multimodal Prehabilitation Based on 5G + Artificial Intelligence Mobile Health mHealth prehabilitation group, ERAS group - Gastric Cancer, Prehabilitation | Not applicable | Not yet recruiting | The Affiliated Hospital of Qingdao University | 490 | 2026-08-31 | 2026-08-10 |
| Inhalational Versus Intravenous Anesthesia on Postoperative Lung Injury in Septic Patients Undergoing Surgery Inhalation Anesthesia, intravenous anesthesia - Sepsis, Lung Injury | Not applicable | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 480 | 2026-08-15 | 2026-05-22 |
| Home-based Whole Course Multimodal Prehabilitation Based on 5G + Artificial Intelligence Mobile Health mHealth prehabilitation group, ERAS group - Gastric Cancer, Prehabilitation | Not applicable | Not yet recruiting | The Affiliated Hospital of Qingdao University | 328 | 2026-08-01 | 2026-08-14 |
| Efficacy and Safety of CDED With Anti-TNF-α Biologics in Crohn's Disease Crohn's Disease Exclusion Diet - Crohn Disease | Not applicable | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 185 | 2026-08-01 | 2026-07-10 |
| A Prospective, Single-Arm Clinical Study of a Dietary Supplement for the Prevention of Acute Radiation-Induced Rectal Injury During Neoadjuvant Chemoradiotherapy for Rectal Cancer Tributyrin - Radiotherapy, Radiation-Induced Complications | Not applicable | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 23 | 2026-07-01 | 2026-09-03 |
| SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC Short-Course Radiotherapy, PD-1 monoclonal antibody, mFOLFOX6 regimen - Rectal Adenocarcinoma, High-Risk Cancer | Phase 3 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 204 | 2026-05-20 | 2026-07-01 |
| Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Video-assisted Thoracoscopic Pneumonectomy Revised-Paravertebral Nerve Block, Control - Video-assisted Thoracoscopic Surgery (VATS), Postoperative Pain | Not applicable | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 200 | 2026-05-06 | 2026-05-08 |
| MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES) Dexmedetomidine, Placebo - Major Abdominal Surgery, Postoperative Delirium (POD) | Phase 2 / Phase 3 | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 400 | 2026-05-01 | 2026-04-20 |
| Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Stoma Closure Revised-Paravertebral Nerve Block - Stoma Closure, Postoperative Pain | Not applicable | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 250 | 2026-04-27 | 2026-05-11 |
| Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Laparoscopic Cholecystectomy Revised-Paravertebral Nerve Block - Benign Gallbladder Disease, Laparoscopic Cholecystectomy | Not applicable | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 250 | 2026-04-27 | 2026-05-11 |
| Improvement Effect of Dexamethasone Enema for Acute Radiation-induced Rectal Injury Experimental Group (dexamethasone enema), Control group (dexamethasone enema) - Acute Radiation Enteritis | Phase 2 | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 40 | 2026-04-24 | 2026-04-23 |
| Real-World Study of IL-23 Inhibitors in Active Crohn's Disease IL-23 inhibitor, TNF inhibitors - Crohn's Disease | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 665 | 2026-04-16 | 2026-07-09 | |
| Akkermansia Muciniphila Combined With Infliximab for Promoting Intestinal Mucosal Healing in Crohn's Disease Infliximab, Akkermansia muciniphila + Infliximab - Crohn's Diseases | Phase 4 | Not yet recruiting | Chinese Medical Association | 400 | 2026-04-01 | 2026-02-17 |
Showing 20 of 288. Sign in to see all of them.
Rectal Neoplasms (46) · Crohn Disease (38) · Colorectal Neoplasms (34) · Stomach Neoplasms (17) · Colitis, Ulcerative (12) · Inflammatory Bowel Diseases (12) · Colonic Neoplasms (8) · Neoplasms (8) · Neoplasm Metastasis (7) · Pathologic Complete Response (6) · Pain, Postoperative (5) · Low Anterior Resection Syndrome (4) · Postoperative Nausea and Vomiting (4) · Adenocarcinoma (3) · Constriction, Pathologic (3)
Oxaliplatin (15) · Fluorouracil (13) · Infliximab (9) · upadacitinib (9) · Drug Therapy (7) · Bevacizumab (6) · Docetaxel (6) · Neoadjuvant Therapy (6) · Surgical Procedures, Operative (6) · Capecitabine (5) · Folfox protocol (5) · Irinotecan (5) · Azathioprine (4) · Immune Checkpoint Inhibitors (4) · Midazolam (4)
China (231) · Italy (1) · Thailand (1)
Jun Huang, MD (6) · Sanqing Jin, MD (6) · Jian Xiao, MD (5) · Ping Lan, MD (4) · Xiangbo Wan, MD, PhD (4) · Zerong Cai, MD (4) · Hong Li, MD (3) · Jun Huang, PhD. (3) · SanQing Jin, MD (3) · Yun-Long Wang, Ph.D (3) · Hu Hao (2) · Jian Xiao (2) · Lei Wang, MD, PhD (2)
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