88 completed, 42 unknown, 35 recruiting, 23 not yet recruiting. 205 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 205 | Completed 88, Unknown 42, Recruiting 35, Not yet recruiting 23, Terminated 7, Withdrawn 6, Active not recruiting 2, Enrolling by invitation 2 |
Follow Mechanical Ventilation: new trials by email Literature Review of Mechanical Ventilation trials Research Report on Mechanical Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Flow-Controlled Ventilation to Improve Postoperative Pulmonary Outcome After Thoracic Surgery Flow-Controlled Ventilation, Volume-Controlled Ventilation - Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs) | Not applicable | Not yet recruiting | Cantonal Hospital of St. Gallen | 140 | 2026-12-01 | 2026-10-20 |
| The Hemodynamic Impact of High-frequency Oscillatory Ventilation and Periodic Sighs in Preterm Infants Superimposed sigh breaths, High frequency ventilation - Preterm, Respiratory Distress Syndrome in Premature Infant | Not applicable | Not yet recruiting | Alexandria University | 100 | 2026-11-15 | 2026-10-27 |
| Planned Operating-Room Extubation After Cardiac Surgery Planned Operating-Room Extubation, Standard Early ICU Extubation - Mechanical Ventilation, Cardiac Surgery | Not applicable | Not yet recruiting | Nova Scotia Health Authority | 336 | 2026-11-01 | 2026-10-15 |
| Effect of PEEP on Indirect Calorimetry in Critically Ill Patients Protocolized PEEP Adjustment - Indirect Calorimetry, Mechanical Ventilation | Not applicable | Not yet recruiting | Vastra Gotaland Region | 20 | 2026-11-01 | 2026-09-01 |
| Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure-Targeted Assist/Control Ventilation Positive end-expiratory pressure 11, Positive end-expiratory pressure 9, Positive end-expiratory pressure 7 - Mechanical Ventilation, Critical Care | Not applicable | Not yet recruiting | Jian-Xin Zhou | 30 | 2026-11-01 | 2026-10-21 |
| Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure Support Ventilation Pressure support 15, Pressure support 13, Pressure support 11 - Mechanical Ventilation, Critical Care | Not applicable | Not yet recruiting | Jian-Xin Zhou | 30 | 2026-11-01 | 2026-10-21 |
| Trcheal High-flow for Weaning From Mechanical Ventilation Oxygen therapy - Tracheostomy, Mechanical Ventilation | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2026-10-01 | 2026-07-20 |
| BURN-ASV Trial: Adaptive Support Ventilation in Severe Burn Injury Adaptive Support Ventilation (ASV), Conventional Lung-Protective Mechanical Ventilation - Burn, Mechanical Ventilation | Not applicable | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 100 | 2026-09-23 | 2026-06-29 |
| Effort of Breathing and Dyssynchrony Burden During Assisted Ventilation in Paediatric Patients Pressure Control Mode, Pressure Support Mode - Mechanical Ventilation, Paediatric Intensive Care | Not applicable | Not yet recruiting | The Hospital for Sick Children | 25 | 2026-09-21 | 2026-09-01 |
| Titration of PS Guided by FI : A Pilot Study FI-guided ventilator support adjustment, Conventional PS titration - Mechanical Ventilation | Not applicable | Recruiting | Capital Medical University | 60 | 2026-09-01 | 2026-10-23 |
| Mechanical Ventilator Adjustments and Patient Dyspnea Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow - Respiratory Failure, Dyspnea During Mechanical Ventilation | Not applicable | Not yet recruiting | Beth Israel Deaconess Medical Center | 20 | 2026-09-01 | 2026-07-14 |
| PERMISSive Lung-protective Ventilation RCT Permissive lung-protective ventilation, Conventional lung-protective ventilation - Invasive Ventilation, Critical Illness | Not applicable | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 926 | 2026-09-01 | 2026-09-23 |
| Effect of Maternal Voice on Pain, Sedation, and Physiological Parameters in Mechanically Ventilated Children Recorded Maternal Voice - Pain, Sedation | Not applicable | Not yet recruiting | TC Erciyes University | 28 | 2026-08-15 | 2026-08-10 |
| Bronchoscopic Airway Clearance for Improving Lung Aeration in Mechanically Ventilated Patients With Atelectasis Flexible Bronchoscopy-Guided Airway Clearance, Usual Airway Care - Atelectasis, Mechanical Ventilation | Not applicable | Recruiting | Southeast University, China | 104 | 2026-08-05 | 2026-10-21 |
| The Impact of Ventilator Synchrony on Muscle Relaxant Consumption and Surgeon Satisfaction During Laparoscopic Cholecystectomy. Non-Synchronized Group (Control), Synchronized group - Muscle Relaxant Consumption, Mechanical Ventilation | Not applicable | Not yet recruiting | Hitham Mohammed Aly Elsayed | 60 | 2026-08-01 | 2026-06-15 |
| Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Consequence and Intraoperative Indicator of Fluid Responsiveness Alveolar Recruitment Maneuver (ARM), Passive Leg Raising (PLR) Test - Hypotension Drug-Induced, General Anesthesia Using Endotracheal Intubation | Not applicable | Not yet recruiting | University of Health Sciences Balikesir Hospital Eduation and Research | 70 | 2026-07-15 | 2026-08-17 |
| Heart Rate Variability for Practitioner Stimulated Reflection and Decision-making Optimisation Critical Participatory Action Intervention with HRV Feedback - Critical Care Nursing, Decision Making | Not applicable | Recruiting | Papworth Hospital NHS Foundation Trust | 20 | 2026-07-14 | 2026-09-18 |
| COMPARE-VENT Feasibility Pilot Study Volume Controlled Mode, Pressure Controlled Mode - Respiration Failure, Cardio Vascular Disease | Not applicable | Recruiting | Mayo Clinic | 75 | 2026-07-01 | 2026-08-10 |
| Mechanical Power During Different Ventilation Modes in Laparoscopic Surgery Volume-Controlled Ventilation (VCV), Pressure-Regulated Volume Control (PRVC) - Laparoscopic Cholecystectomy, Mechanical Ventilation | Not applicable | Recruiting | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 80 | 2026-07-01 | 2026-07-08 |
| Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery FCV Group, VCV Group - Lumbar Disc Herniation Surgery, Mechanical Ventilation | Not applicable | Recruiting | Ankara Etlik City Hospital | 80 | 2026-05-28 | 2026-06-01 |
Showing 20 of 205. Sign in to see all of them.
Critical Illness (25) · Respiratory Insufficiency (22) · Respiratory Distress Syndrome (13) · Pulmonary Atelectasis (6) · Obesity (5) · Pneumonia, Ventilator-Associated (5) · Respiratory Aspiration (5) · Agnosia (4) · Pain (4) · Brain Injuries (3) · COVID-19 (3) · Delirium (3) · Sepsis (3) · Shock (3) · Ventilator-Induced Lung Injury (3)
Pathological Conditions, Signs and Symptoms (63) · Respiratory Tract Diseases (58) · Pathologic Processes (43) · Respiration Disorders (38) · Lung Diseases (34) · Disease Attributes (30) · Signs and Symptoms (28) · Nervous System Diseases (18) · Neurologic Manifestations (17) · Infections (14) · Neurobehavioral Manifestations (10) · Respiratory Tract Infections (10) · Cardiovascular Diseases (9) · Mental Disorders (9) · Heart Diseases (7)
Continuous Positive Airway Pressure (4) · Dexmedetomidine (4) · Respiration, Artificial (4) · Standard of Care (3) · Educational Status (2) · Positive-Pressure Respiration (2) · Propofol (2) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Acupressure (1) · Anesthetics, Local (1) · Brain-Computer Interfaces (1) · Control Groups (1) · Deep Sedation (1) · Diagnostic Imaging (1) · Ear Protective Devices (1)
Capital Medical University (7) · Jian-Xin Zhou (6) · University Hospital, Clermont-Ferrand (6) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (4) · Assistance Publique - Hôpitaux de Paris (3) · Assiut University (3) · Alexandria University (2) · Ankara Etlik City Hospital (2) · Beth Israel Deaconess Medical Center (2) · Brazilian Institute of Higher Education of Censa (2) · Centre Hospitalier Régional d'Orléans (2) · Centre d'Investigation Clinique et Technologique 805 (2) · Erasmus Medical Center (2) · Hospices Civils de Lyon (2) · Hospital Clinic of Barcelona (2)
China (30) · France (26) · United States (25) · Turkey (Türkiye) (17) · Brazil (12) · Netherlands (10) · Canada (9) · Taiwan (9) · Egypt (7) · Italy (7) · Spain (6) · Austria (4) · Belgium (4) · Greece (4) · Chile (3)
Annemijn Jonkman, PhD (2) · Brian Fuller, MD (2) · Jian-Xin Zhou (2) · Jian-Xin Zhou, MD, PhD (2) · Alberto Zanella, MD (1) · Alejandro Bruh Bruhn (1) · Alexandre B Cavalcanti, MD, PhD (1) · Alexandre Biasi Cavalcanti, MD, PhD (1) · Amal R Ali, MD (1) · Ana Paula C Carlotti, MD, PhD (1) · Annop Piriyapatsom, MD (1) · Antonello Penna, MD/PhD (1) · Antonius H. Pudjiadi, MD, PhD (1)
PMID 14707570, PMID 15942342, PMID 18492267, PMID 19255741, PMID 21406514, PMID 22976857, PMID 23152333, PMID 24670166, PMID 24687313, PMID 25232415, PMID 25425705, PMID 26471790, PMID 26515515, PMID 26938617, PMID 28030555, PMID 28186222, PMID 28259058, PMID 29336938, PMID 29404723, PMID 29777534, PMID 31272379, PMID 31618346, PMID 32376293, PMID 33306936, PMID 33328261, PMID 33368159, PMID 33688090, PMID 33980526, PMID 34609548, PMID 35523498, PMID 35589091, PMID 35607967, PMID 35660485, PMID 35767435, PMID 35866657, PMID 36564808, PMID 36958363, PMID 36963903, PMID 36964614, PMID 37487152, PMID 38001507, PMID 38046681, PMID 38342951, PMID 38528475, PMID 38631841, PMID 38715118, PMID 38737762, PMID 38849605, PMID 38865147, PMID 39076742
5KL2TR002734-03 (1), K23GM068842 (1), K23HL175246 (1), R01HL162721 (1), R34HL150404 (1)