232 completed, 68 unknown, 42 recruiting, 31 terminated. 148 Not applicable, 55 Phase 3, 42 Phase 2, 37 Phase 4, 11 Phase 1.
Follow Pneumonia, Ventilator-Associated: new trials by email Literature Review of Pneumonia, Ventilator-Associated trials Research Report on Pneumonia, Ventilator-Associated
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| Resistance-Optimised Antimicrobial Dosing in Critically Ill Patients, a Randomised Controlled Trial Resistance-Optimised Precision Dosing, Standard Care Dosing - Hospital-acquired Pneumonia (HAP), Ventilator-Associated Pneumonia (VAP) | Not applicable | Not yet recruiting | The University of Queensland | 610 | 2026-11-01 | 2026-09-15 |
| Role of Inhaled Polymyxin as an Adjunct to Intravenous Therapy in Multidrug Resistant Ventilator-associated Pneumonia in Stroke Patients Inhaled colistin, Saline - Ventilator Associated Pneumonia ( VAP) | Early Phase 1 | Not yet recruiting | Ain Shams University | 78 | 2026-10-10 | 2026-10-08 |
| Tobramycin Nebulization to Prevent Multidrug-Resistant Ventilator-Associated Pneumonia Tobramycin inhalation solution, 0.9% Sodium Chloride Placebo - Pneumonia, Ventilator-Associated | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 574 | 2026-10-07 | 2026-10-02 |
| Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury Closed endotracheal suction system, Open endotracheal suction - Ventilator-associated Pneumonia, Traumatic Brain Injury | Not applicable | Not yet recruiting | Minia University | 120 | 2026-10-04 | 2026-10-20 |
| National Surveillance and Prevention of Neonatal VAP Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD) | Not yet recruiting | University of Alberta | 1500 | 2026-10-01 | 2026-06-25 | |
| BIS in ICU Interventional Study Device-guided sedation, standard sedation practice - Cardiac Surgical Procedures (Postoperative Population), Critical Illness | Not applicable | Not yet recruiting | Medical University of Graz | 144 | 2026-10-01 | 2026-10-07 |
| Mobile-Based Microlearning for Improving ICU Nurses' Adherence to Ventilator-Associated Pneumonia Prevention Protocols Mobile-Based Microlearning Program, Routine Education - Ventilator-Associated Pneumonia | Not applicable | Not yet recruiting | Alexandria University | 110 | 2026-10-01 | 2026-10-21 |
| Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily - Intubation Complication, Stroke, Ischemic | Phase 4 | Not yet recruiting | Hospital San Carlos, Madrid | 60 | 2026-09-15 | 2026-08-06 |
| Systemic Traditional Chinese Medicine in Multidrug-Resistant Bacterial Pneumonia Multi Drug Resistant Infections, Pneumnia | Not yet recruiting | Henan University of Traditional Chinese Medicine | 528 | 2026-08-01 | 2026-07-28 | |
| Procalcitonin Versus Serum Zinc for Diagnosis of Ventilator-Associated Pneumonia in ICU Patients Serum Procalcitonin Measurement, Serum Zinc Measurement - Ventilator Acquired Pneumonia | Not yet recruiting | Sohag University | 84 | 2026-07-07 | 2026-07-10 | |
| Early Identification of Pathogens in Children With Respiratory Tract Infection by Mechanical Ventilation Using mNGS mNGS diagnose of VAP - VAP - Ventilator Associated Pneumonia | Not yet recruiting | Children's Hospital of Fudan University | 400 | 2026-07-01 | 2026-02-17 | |
| Probiotic Role in Prevention of Ventilator Associated Pneumonia in Critically- Ill Children Admitted at Pediatric Intensive Care Unit Probiotics, Standard management - Probiotic, Ventilator Associated Pneumonia | Not applicable | Recruiting | Tanta University | 68 | 2026-07-01 | 2026-09-29 |
| EARLY Antibiotics aDAptation in Severe Pneumonia(The EARLY ADAPT Study) PCR multiplex BioFire Pneumonia plus - VAP - Ventilator Associated Pneumonia, Antibiotic | Not applicable | Not yet recruiting | University Hospital, Geneva | 170 | 2026-06-05 | 2026-04-29 |
| Inhaled Amikacin Versus Placebo in Patients With Ventilator-associated Tracheobronchitis Optimized and protocolized nebulization procedure. - Ventilator-Associated Pneumonia, Ventilator-Associated Tracheobronchitis | Phase 3 | Not yet recruiting | University Hospital, Tours | 250 | 2026-06-01 | 2026-06-24 |
| Impact of BioFire FilmArray Pneumonia Panel vs Routine Diagnostics on Antimicrobial Outcomes (DOOR-MAT) Multiplex PCR-based pneumonia panel (BIOFIRE® FILMARRAY® Pneumonia Panel) - Pneumonia - Bacterial | Not applicable | Recruiting | Hospital de Clinicas de Porto Alegre | 150 | 2026-05-20 | 2026-09-17 |
| Microbiome-guided Prophylaxis to Reduce Ventilator-Associated Pneumonia in Intensive Care Units: A Pilot Randomized Controlled Trial Microbiome-guided inhaled antibiotic prophylaxis, Placebo - Critical Illness, Mechanical Ventilation | Phase 2 | Not yet recruiting | University of Calgary | 70 | 2026-05-01 | 2026-03-11 |
| ClusterVAP: Multicentre Proteomic Endotyping of Ventilator-associated Pneumonia Ventilator Acquired Pneumonia, Mechanical Ventilation Complication | Recruiting | Region Skane | 400 | 2026-05-01 | 2026-06-30 | |
| Innate Immune Immunoparalysis and Ventilator-Associated Pneumonia in Critically Ill Elderly Patients Intubated ICU Patients, Ventilator Associated Pneumonia ( VAP) | Recruiting | Hospital Universitari de Bellvitge | 170 | 2026-05-01 | 2026-05-19 | |
| Combined Use of a Respiratory Multiplex PCR and Algorithm-based Therapy to Improve Early Optimization of Antibiotic Therapy in Critically Ill Patients With Ventilator-associated Pneumonia strategy combining respiratory mPCR and algorithm-based therapy developed using local epidemiology - Ventilator Associated Pneumonia ( VAP) | Phase 4 | Recruiting | Centre Hospitalier Universitaire de Nīmes | 124 | 2026-03-27 | 2026-10-13 |
Showing 20 of 417. Sign in to see all of them.
Pneumonia (56) · Healthcare-Associated Pneumonia (53) · Cross Infection (28) · Critical Illness (21) · Sepsis (16) · Infections (15) · Pneumonia, Bacterial (15) · COVID-19 (12) · Respiratory Tract Infections (11) · Urinary Tract Infections (9) · Pseudomonas Infections (7) · Brain Injuries, Traumatic (6) · Communicable Diseases (6) · Community-Acquired Pneumonia (6)
Disease Attributes (417) · Pathologic Processes (417) · Pathological Conditions, Signs and Symptoms (417) · Iatrogenic Disease (416) · Lung Diseases (416) · Respiratory Tract Diseases (416) · Respiratory Tract Infections (406) · Infections (402) · Cross Infection (389) · Healthcare-Associated Pneumonia (364) · Pneumonia (361) · Bacterial Infections and Mycoses (41) · Bacterial Infections (35) · Systemic Inflammatory Response Syndrome (23) · Inflammation (22)
Chlorhexidine (10) · Colistin (10) · Doripenem (10) · Vancomycin (9) · Saline Solution (7) · Toothbrushing (7) · Linezolid (6) · Meropenem (6) · chlorhexidine gluconate (6) · Amikacin (5) · Cilastatin, Imipenem Drug Combination (5) · Sodium Chloride (5) · Standard of Care (5) · Amoxicillin-Potassium Clavulanate Combination (4) · Ceftriaxone (4)
Assistance Publique - Hôpitaux de Paris (9) · Assiut University (9) · Pfizer (8) · Ain Shams University (5) · Fondation Hôpital Saint-Joseph (5) · University Hospital, Lille (5) · Region Skane (4) · University of Thessaly (4) · Alexandria University (3) · Basilea Pharmaceutica (3) · Cairo University (3) · Centre Hospitalier Departemental Vendee (3) · Centre Hospitalier Universitaire de Nīmes (3) · Hospital do Coracao (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3)
France (80) · United States (62) · Egypt (28) · China (25) · Spain (25) · Brazil (20) · Turkey (Türkiye) (20) · Canada (18) · Italy (17) · Greece (15) · India (14) · Thailand (14) · Belgium (12) · Israel (11) · United Kingdom (11)
Marin Kollef, MD (3) · Sutep Jaruratanasirikul, MD (3) · Daren Heyland, MD (2) · Deborah J Cook, MD (2) · Jean-Damien Ricard, MD, PhD (2) · Lucy B Palmer, MD (2) · Nazima Pathan, FRCPCH PhD (2) · Philippe Seguin, MD, PhD (2)
PMID 17872488, PMID 24723282, PMID 26472037, PMID 26836896, PMID 30808293, PMID 33960817, PMID 34155899, PMID 34792787, PMID 35076335, PMID 38676438, PMID 41251370, PMID 10816031, PMID 11445675, PMID 11778260, PMID 11888973, PMID 11934711, PMID 1424930, PMID 14707570, PMID 15345979, PMID 15447947, PMID 15865552, PMID 15942342, PMID 17994522, PMID 18096127, PMID 18421435, PMID 18641114, PMID 18707849, PMID 18714060, PMID 18719064, PMID 18752007, PMID 18951395, PMID 18990201, PMID 18991508, PMID 19237884, PMID 19482956, PMID 19605577, PMID 19670912, PMID 19698010, PMID 19765321, PMID 20125046, PMID 20211892, PMID 20302428, PMID 20407057, PMID 20459721, PMID 20463812, PMID 20522788, PMID 20522796, PMID 20584505, PMID 20693381, PMID 20936977
2016 (3), 2025 (2), R01NR007652 (2), 2009 (1), 2014 (1), 2015 (1), 2017 (1), 2018 (1), 2019 (1), 2023 (1), 5UL1TR002240-05 (1), 5UM1AI104681 (1), K24AI141580 (1), R01DE014685 (1), R01GM115353 (1)