15 completed, 11 recruiting, 5 unknown, 3 not yet recruiting. 34 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow Brain-Computer Interfaces: new trials by email Literature Review of Brain-Computer Interfaces trials Research Report on Brain-Computer Interfaces
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia BrainGate Neural Interface System - Expressive Aphasia, Aphasia Following Cerebral Infarction | Not applicable | Not yet recruiting | Leigh R. Hochberg, MD, PhD. | 5 | 2026-11-01 | 2026-10-22 |
| Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device. Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental - Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline | Early Phase 1 | Not yet recruiting | Noah Tech, Corp. | 600 | 2026-09-01 | 2026-03-10 |
| Using Motor Imagery-based Brain-computer Interface With Multiple Sclerosis Patients. Brain Computer Interface - Multiple Sclerosis | Not applicable | Not yet recruiting | Pasquale Arpaia | 40 | 2026-07-01 | 2026-03-16 |
| Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system - Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete) | Not applicable | Recruiting | Case Western Reserve University | 3 | 2026-01-13 | 2026-02-19 |
| Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation for Peripheral Facial PalsyStimulation in the Treatment of Peripheral Facial Palsy Brain-Computer Interface （BCI）, Pulsed Radiofrequency （PRF）, Standard Therapy - Peripheral Facial Palsy, Pulsed Radiofrequency | Not applicable | Enrolling by invitation | Nanjing Medical University | 30 | 2025-11-30 | 2026-01-08 |
| Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface Brain-computer interface with neurofeedback with 3D game sessions - Acquired Brain Injury Including Stroke, Epilepsy | Not applicable | Recruiting | KK Women's and Children's Hospital | 70 | 2025-11-01 | 2026-09-18 |
| BCI@Home: Brain Computer Interface Solutions to Enable Youth Living With Severe Disabilities Brain computer interface - Cerebral Palsy, Pediatric Stroke | Not applicable | Recruiting | University of Calgary | 18 | 2025-11-01 | 2026-05-05 |
| Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game Brain-Computer Interface (BCI)-HABIT-VR, Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR) - Healthy Children, CP (Cerebral Palsy) | Not applicable | Recruiting | University of Nebraska | 51 | 2025-07-30 | 2026-09-03 |
| Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury Brain-Machine Interface - Spinal Cord Injury, Able Bodied | Not applicable | Enrolling by invitation | José Gabriel da Silva Figueiredo | 20 | 2025-07-22 | 2026-07-29 |
| Gait Rehabilitation in Stroke Patients Using Functional Electrical Stimulation and Visual Feedback recoveriX, Control - Stroke | Not applicable | Completed | g.tec medical engineering GmbH | 30 | 2025-06-03 | 2026-04-17 |
| fNIRS-BCI Neurofeedback in Stroke Rehabilitation Brain-computer interface, Sham brain-computer interface - Stroke | Not applicable | Recruiting | The Hong Kong Polytechnic University | 44 | 2024-12-12 | 2025-08-22 |
| Neurofeedback Rehabilitation With FES and VR for PD Brain-Computer Interface with FES and VR, Motor imagery with Functional Electrical Stimulation and Virtual Reality feedback - Parkinson Disease | Not applicable | Completed | g.tec medical engineering GmbH | 30 | 2024-12-09 | 2026-09-03 |
| BCI-Guided Tibialis Anterior FES for Gait Training in Spinal Cord Injury Ankle Dorsiflexion Rehabilitation - Spinal Cord Injury | Not applicable | Active not recruiting | Santos Dumont Institute | 10 | 2024-11-01 | 2026-08-17 |
| Effects of Motor Imagery and Action Observation on Upper Limb Motor Chances and Cognitive Chances in Parkinson's Disease Motor Imagery, Action Observation, Exoskeletons - Parkinson Disease | Not applicable | Completed | Federal University of Health Science of Porto Alegre | 60 | 2023-02-01 | 2025-04-25 |
| Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation Brain-Computer Interface, Sham Brain-Computer Interface - Cervical Spinal Cord Injury | Not applicable | Recruiting | Instituto Nacional de Rehabilitacion | 32 | 2022-08-01 | 2025-06-25 |
| EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke NeuroExo co-robot neurorehabilitation system - Stroke, Hemiparesis | Not applicable | Unknown | University of Houston | 30 | 2022-04-25 | 2022-05-16 |
| BCI for Hemiparetic Upper Extremities in Patients Due to Stroke Brain Computer Interface/ Functional Electrical Stimulation/ Virtual Reality - Stroke, Brain Computer Interface | Not applicable | Completed | The Hong Kong Polytechnic University | 30 | 2021-08-11 | 2026-06-08 |
| Validation of a Brain-Computer Interface for Stroke Neurological Upper Limb Rehabilitation Brain-Computer Interface, Sham Brain-Computer Interface - Stroke, Ischemic, Stroke | Not applicable | Completed | Instituto Nacional de Rehabilitacion | 23 | 2021-03-16 | 2024-07-12 |
| An Online Home-based Intervention for Anxiety Regulation Brain-Computer Interface - Anxiety | Not applicable | Unknown | Duke-NUS Graduate Medical School | 30 | 2021-01-05 | 2021-11-17 |
Showing 20 of 40. Sign in to see all of them.
Quadriplegia (8) · Spinal Cord Injuries (8) · Stroke (7) · Amyotrophic Lateral Sclerosis (4) · Brain Stem Infarctions (4) · Alzheimer Disease (3) · Cognitive Dysfunction (3) · Dementia (3) · Muscular Dystrophies (3) · Parkinson Disease (3) · Cerebral Palsy (2) · Paresis (2) · Anxiety Disorders (1) · Aphasia (1) · Aphasia, Broca (1)
Duke-NUS Graduate Medical School (3) · University of Michigan (3) · Instituto Nacional de Rehabilitacion (2) · Leigh R. Hochberg, MD, PhD. (2) · Michael Boninger (2) · National Healthcare Group, Singapore (2) · The Hong Kong Polytechnic University (2) · g.tec medical engineering GmbH (2) · Beijing Tiantan Hospital (1) · Case Western Reserve University (1) · Centre d'Investigation Clinique et Technologique 805 (1) · Chinese University of Hong Kong (1) · Federal University of Health Science of Porto Alegre (1) · Johns Hopkins University (1) · José Gabriel da Silva Figueiredo (1)
United States (14) · Singapore (6) · China (3) · Hong Kong (3) · Austria (2) · Brazil (2) · Canada (2) · France (2) · Mexico (2) · Italy (1) · Portugal (1) · Russia (1)
Jessica Cantillo-Negrete, PhD (2) · Michael L Boninger, MD (2) · Tih Shih Lee, MD, PhD (2) · Ahad Behboodi, PhD (1) · Choon Guan Lim (1) · David Orlikowski, MDPhD (1) · Emily Graczyk, Ph.D. (1) · Felipe A Medeiros, MD, PhD (1) · Gerard Francisco, MD (1) · Guo-Guang Zhao, M.D. (1) · Henry Tseng, MD, PhD (1) · Jane E. Huggins, PhD (1) · Jane Huggins, PhD (1) · Janis J Daly, PhD, MS (1) · Jennifer L Collinger, PhD (1)
PMID 26987662, PMID 29209023, PMID 29553484, PMID 32494819, PMID 34847547, PMID 21436513, PMID 22596161, PMID 23115630, PMID 23253623, PMID 23838067, PMID 24260218, PMID 24626608, PMID 25385765, PMID 25514320, PMID 26413781, PMID 27900953, PMID 28220753, PMID 28278476, PMID 28363483, PMID 29160240, PMID 29363625, PMID 29761128, PMID 30429772, PMID 32122766, PMID 33770779, PMID 34793641, PMID 35234665, PMID 35287119, PMID 35875789, PMID 36639237, PMID 36698168, PMID 37007675, PMID 38579696, PMID 38642555, PMID 39141853, PMID 39720868, PMID 39808922, PMID 39854845, PMID 39883960, PMID 40033447, PMID 40064104, PMID 40106898, PMID 40193313, PMID 40280150, PMID 40506548, PMID 40606836, PMID 40832410, PMID 41337760, PMID 42349111
2023 (1), P20GM109090 (1), R01DC009899 (1), R01DC014034 (1), R01EY029885 (1), R01HD117313 (1), R15HD117277 (1), U01DC017844 (1), U01NS123101 (1), UH2NS095548 (1)