57 completed, 21 unknown, 8 recruiting, 6 not yet recruiting. 50 Not applicable, 5 Phase 2, 5 Phase 3, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery. Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy - Fraily, Abdominal Surgery | Not applicable | Not yet recruiting | Ente Ospedaliero Ospedali Galliera | 100 | 2026-09-01 | 2026-03-20 |
| Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery Mechanical Ventilation (PEEP) - Lumbar Disc Herniation, Spinal Surgery | Not applicable | Not yet recruiting | Harran University | 60 | 2026-08-15 | 2026-08-11 |
| Predictors and Outcomes of Ventilated Hospital-acquired Pneumonia mechanical ventilation (MV) - Hospital Acquired Pneumonia | Recruiting | Assiut University | 151 | 2026-06-01 | 2026-06-25 | |
| The Study Seeks to Determine Potential Correlations Between Ventilation and Hematological Alterations, Contributing to a Better Understanding of Its Physiological Effects and Optimizing Patient Management in Critical Care Settings. complete blood tests, mechanical ventilation (MV) - Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome | Not yet recruiting | Assiut University | 60 | 2026-04-01 | 2025-06-22 | |
| Cerebral Hemodynamics and Oxygenation in Critically Ill Patients mechanical ventilation, Sedation - Septic Shock | Withdrawn | Centre Hospitalier Universitaire de Nice | 2026-03-01 | 2026-05-26 | ||
| Minimal Flow Anesthesia and Infection Risk Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG - Minimal Flow Anesthesia, General Anaesthesia | Not applicable | Completed | Ankara City Hospital Bilkent | 140 | 2025-08-01 | 2026-10-05 |
| Accuracy of the Set Tidal Volume During Intraoperative Mechanical Ventilation Mechanical ventilation - Surgery, Mechanical Ventilation Pressure High | Withdrawn | Joseph D. Tobias | 2025-06-01 | 2025-10-27 | ||
| multipaRameter mOnitoring systeM for sedAtion iNThe ICu Sedative - Sedation Complication | Recruiting | Pontificia Universidad Catolica de Chile | 80 | 2025-02-14 | 2025-06-08 | |
| Comparison of Respiratory Support for Acute Pulmonary Edema mechanical ventilation - Pulmonary Edema - Acute | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 200 | 2025-02-06 | 2025-02-11 | |
| Desflurane Potentially Induces Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Perioperative Procedures by Modulating Cdc42 and Clock Proteins Desflurane Inhalation, mechanical ventilation (MV) - Avascular Necrosis of the Femoral Head, Coronary Artery Disease (CAD) | Not applicable | Not yet recruiting | Xiaguang Duan | 60 | 2025-02-01 | 2025-01-14 |
| The Ventilation During In-hospital Cardiac Arrest Study Positive pressure ventilation during cardiopulmonary resuscitation - Cardiac Arrest (CA), In-Hospital Cardiac Arrest | Recruiting | University of Aarhus | 900 | 2025-02-01 | 2026-03-30 | |
| "Group Based Reverse OSCE" for Teaching Mechanical Ventilation mechanical ventilation (MV) - Medical Education, Nursing Students | Not applicable | Completed | Torbat Heydariyeh University of Medical Sciences | 70 | 2025-01-10 | 2025-12-10 |
| Compare Between APRV and Bipap Ventilation in ARDS Patients mechanical ventilation (MV) - ARDS: Acute Respiratory Distress Syndrome, ARDS | Not applicable | Not yet recruiting | Ain Shams University | 50 | 2024-12-01 | 2025-01-01 |
| Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS opioid based strategy, opioid-free strategy, Laryngeal mask airway; Preserved spontaneous breathing - Video-assisted Thoracoscopic Lung Surgery；Anesthesia | Not applicable | Recruiting | Tongji Hospital | 480 | 2024-10-01 | 2025-01-03 |
| Investigation of the Optimum PEEP Mechanical Power Relationship Mechanical Ventilation (MV) with Low PEEP, Mechanical Ventilation (MV) with Optimum PEEP - Mechanical Ventilation, Mechanical Power | Completed | Kocaeli City Hospital | 101 | 2024-09-12 | 2025-11-24 | |
| Outcome and Predictors of Mortality of Patients on Prolonged Mechanical Ventilation Mechanical ventilation - Outcome | Unknown | Wollo University | 323 | 2024-07-15 | 2024-04-30 | |
| Mechanical Ventilation on Hippocampus Mechanical ventilation - Mechanical Ventilation Complication, Brain Injuries | Unknown | Beijing Sanbo Brain Hospital | 20 | 2024-05-08 | 2024-08-09 | |
| The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury General Anesthesia, Spinal Anesthesia - Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery | Not applicable | Unknown | Sisli Hamidiye Etfal Training and Research Hospital | 100 | 2024-04-05 | 2024-07-23 |
| Hemodynamic Effects of Apnoeic Oxygenation With High-flow Nasal Oxygen in Adults Undergoing Laryngeal Surgery Apnoeic oxygenation with high-flow nasal oxygen, Mechanical ventilation - Laryngeal Disease | Not applicable | Completed | Region Stockholm | 20 | 2024-03-25 | 2026-05-15 |
| CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma mechanical ventilation - Wounds and Injuries, Ventilation Therapy; Complications | Completed | Jinling Hospital, China | 1023 | 2023-10-01 | 2024-04-01 |
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Respiratory Insufficiency (13) · Respiratory Distress Syndrome (11) · Respiratory Aspiration (8) · Acute Lung Injury (7) · Heart Arrest (3) · Pneumonia (3) · Apnea (2) · Brain Injuries (2) · COVID-19 (2) · Cholecystitis (2) · Critical Illness (2) · Laryngeal Diseases (2) · Lung Injury (2) · Pneumonia, Ventilator-Associated (2) · Pulmonary Disease, Chronic Obstructive (2)
Assistance Publique - Hôpitaux de Paris (5) · Assiut University (4) · Mansoura University (4) · Policlinico Hospital (4) · Hospital Universitario de Gran Canaria Doctor Negrín (3) · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (3) · Ain Shams University (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · University Hospital, Clermont-Ferrand (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · AlRefaey Kandeel (1) · Althaia Xarxa Assistencial Universitària de Manresa (1) · Ankara City Hospital Bilkent (1) · Asociacion Latinoamericana de Torax (1) · Ataturk Training and Research Hospital (1)
France (14) · China (12) · Egypt (10) · Italy (10) · United States (8) · Spain (6) · Turkey (Türkiye) (6) · Canada (3) · Denmark (3) · Argentina (2) · Brazil (2) · Chile (2) · Germany (2) · Netherlands (2) · Sweden (2)
Davide Chiumello, MD (3) · Lai Jiang, chief doctor (2) · Ahmet Yuksek, Md (1) · Alain Kalmar, MD, PhD (1) · Alexandre Teruya, MD, PhD (1) · Alfredo Secchi, M.D. (1) · Antonello Penna, MD/PhD (1) · Ary Serpa Neto, MD, MSc, PhD (1) · Asher Mendelson, Ph.D. (1) · Basak Pehlivan, Asoc Prof (1) · Chiara Robba, MD (1) · Daniel P Lammertse, MD (1) · Daniel S Cesar, MD (1)
PMID 23093163, PMID 10424561, PMID 10712328, PMID 10816184, PMID 14525802, PMID 15187505, PMID 15636651, PMID 16394778, PMID 16517337, PMID 16870913, PMID 17668184, PMID 17893630, PMID 17962636, PMID 18451319, PMID 18786243, PMID 19636971, PMID 19841125, PMID 19841457, PMID 20055989, PMID 20116842, PMID 20138299, PMID 20802164, PMID 21045639, PMID 21463263, PMID 21542927, PMID 22166673, PMID 22491953, PMID 22797452, PMID 22850883, PMID 23361625, PMID 23385321, PMID 23596346, PMID 23764865, PMID 23880084, PMID 25058504, PMID 25466352, PMID 25484947, PMID 25978326, PMID 26643098, PMID 26947624, PMID 27179847, PMID 27654000, PMID 27717861, PMID 28323236, PMID 29508706, PMID 29561278, PMID 29715485, PMID 30139899, PMID 31123002, PMID 31399381
2015 (1), R21EB016869 (1), U01AI126610 (1), U01HL062514 (1)