27 completed, 5 unknown, 3 not yet recruiting, 1 enrolling by invitation. 21 Not applicable, 7 Phase 4, 3 Phase 2, 3 Phase 3.
Follow Major Abdominal Surgery: new trials by email Literature Review of Major Abdominal Surgery trials Research Report on Major Abdominal Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Preoperative Parenteral Nutrition With Omega-3 Fish Oil Lipid Emulsion on Postoperative Outcomes in Patients Undergoing Major Abdominal Surgery ω-3 fish oil lipid emulsion, Conventional lipid without ω-3 fish oil - Parenteral Nutrition, Nutritional Status | Phase 4 | Not yet recruiting | Second Affiliated Hospital of Nanchang University | 158 | 2026-10-01 | 2026-10-16 |
| MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES) Dexmedetomidine, Placebo - Major Abdominal Surgery, Postoperative Delirium (POD) | Phase 2 / Phase 3 | Not yet recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 400 | 2026-05-01 | 2026-04-20 |
| Effect of taVNS on Perioperative Anxiety in Major Abdominal Surgery transauricular auricular vagus nerve stimulation - Perioperative Anxiety, Major Abdominal Surgery | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 282 | 2026-05-01 | 2026-05-19 |
| Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Ventilation Different interval of PARM - Major Abdominal Surgery, Atelectasis | Not applicable | Enrolling by invitation | Sixth Affiliated Hospital, Sun Yat-sen University | 52 | 2025-12-10 | 2026-05-15 |
| Glycocalyx Monitoring in Major Abdominal Surgery Cytoreduction surgery with Hyperthermic Intraperitoneal Chemotherapy, Cephalic DuodenoPancreatectomy - Major Abdominal Surgery | Completed | University Hospital, Rouen | 78 | 2022-07-05 | 2026-05-22 | |
| Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients alveolar recruitment maneuver - Cardiac Output, Decreased Cardiac Output | Not applicable | Completed | University Hospital, Clermont-Ferrand | 20 | 2022-03-09 | 2023-06-18 |
| Persistent Opioid Consumption After Major Abdominal Surgery and Its Determinants Questionnaires - Major Abdominal Surgery, Chronic Pain | Completed | Centre hospitalier de l'Université de Montréal (CHUM) | 700 | 2022-02-13 | 2025-02-12 | |
| Preoperative Oral Carbohydrate Loading Versus Fasting in Patients Undergoing Major Abdominal Surgery Placebo drink, Carbohydrate - Carbohydrate, Fasting | Not applicable | Unknown | Tanta University | 54 | 2022-01-01 | 2024-02-06 |
| Immunomodulatory Effects of Dexmedetomidine Infusion Dexmedetomidine, 0.9% sodium chloride - Major Abdominal Surgery | Not applicable | Unknown | Alexandria University | 100 | 2022-01-01 | 2022-06-01 |
| Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Postoperative Organ Dysfunction Ephedrine, Norepinephrine - Norepinephrine, Hypotension | Phase 3 | Completed | Centre Hospitalier Universitaire, Amiens | 500 | 2021-11-17 | 2025-12-03 |
| Effects of Lavender Aromatherapy and Cold Application on Pain During Drain Removal cold application, lavender oil inhalation, oxygen administration - Major Abdominal Surgery | Not applicable | Completed | Muğla Sıtkı Koçman University | 121 | 2021-09-01 | 2022-06-21 |
| Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation Vasopressin, Arginine - Major Abdominal Surgery, General Anesthesia | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 20 | 2021-06-09 | 2022-12-05 |
| Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block Triamcinolone, Methylprednisolone, bupivacaine - Major Abdominal Surgery | Phase 2 / Phase 3 | Completed | ghada fouad | 84 | 2020-07-15 | 2021-03-03 |
| Bolus Versus Continuous Enteral Tube Feeding Quadriceps Muscle Layer Fitness, Muscle Strength, Acute Physiology and Chronic Health Evaluation - Trauma Injury, Major Abdominal Surgery | Not applicable | Completed | University Hospital Ostrava | 60 | 2019-10-01 | 2022-12-07 |
| ValidationTurkishVersionQualityofRecovery-15 Quality of Recovery 15 questionnaire - Major Abdominal Surgery, Patient-reported Outcome | Completed | Ankara University | 510 | 2019-09-01 | 2024-06-13 | |
| Ketamine Versus Propofol Effect on the Immune-mediatory Response for Abdominal Surgery Ketamine, Propofol - Major Abdominal Surgery | Not applicable | Unknown | Mansoura University Hospital | 36 | 2019-01-10 | 2019-01-07 |
| Can the Use of Ear Plugs and Eye Masks Help to Improve Sleep Quality After Major Abdominal Surgery? Ear plugs and eye masks - Sleep, Major Abdominal Surgery | Not applicable | Completed | Singapore General Hospital | 100 | 2018-08-29 | 2019-10-14 |
| Preoperative Intravenous Iron Infusion to Reduce Post-surgical Complications: a Pilot Randomised Control Trial Ferric carboxymaltose, Ferrous Fumarate - Anemia, Major Abdominal Surgery | Phase 4 | Unknown | Singapore General Hospital | 60 | 2017-11-22 | 2018-12-05 |
| Individualized Goal-directed Sufentanil Administration Versus Standard Therapy in Patients Undergoing Major Abdominal Surgery Analgesia Nociception Index (ANI)-guided sufentanil administration - Major Abdominal Surgery | Not applicable | Completed | University Hospital, Clermont-Ferrand | 128 | 2017-07-04 | 2023-10-16 |
| Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine TAP block, Epidural analgesia, EXPAREL - Pain, Postoperative, Major Abdominal Surgery | Not applicable | Completed | The Cleveland Clinic | 514 | 2016-12-01 | 2024-01-31 |
Showing 20 of 37. Sign in to see all of them.
Accidental Injuries (1) · Anemia (1) · Cardiac Output, Low (1) · Chronic Pain (1) · Diabetes Insipidus (1) · Emergence Delirium (1) · Fasting (1) · Hyperphagia (1) · Hypotension (1) · Inflammation (1) · Lung Diseases (1) · Pain (1) · Pain, Postoperative (1) · Pancreatitis (1) · Parasomnias (1)
Pathological Conditions, Signs and Symptoms (10) · Pathologic Processes (6) · Signs and Symptoms (6) · Neurologic Manifestations (4) · Cardiovascular Diseases (2) · Pain (2) · Postoperative Complications (2) · Respiratory Tract Diseases (2) · Behavior (1) · Confusion (1) · Delirium (1) · Digestive System Diseases (1) · Endocrine System Diseases (1) · Feeding Behavior (1) · Female Urogenital Diseases (1)
Standard of Care (3) · Bupivacaine (2) · Dexmedetomidine (2) · Norepinephrine (2) · Analgesia, Epidural (1) · Anesthesia, General (1) · Arginine Vasopressin (1) · Atropine (1) · Carbohydrates (1) · Cytidine Diphosphate (1) · Dobutamine (1) · Ear Protective Devices (1) · Echocardiography, Doppler (1) · Enteral Nutrition (1) · Ephedrine (1)
University Hospital Ostrava (3) · University Hospital, Clermont-Ferrand (3) · Singapore General Hospital (2) · Sixth Affiliated Hospital, Sun Yat-sen University (2) · The Cleveland Clinic (2) · Alexandria University (1) · Ankara University (1) · Centre Hospitalier Universitaire de Nīmes (1) · Centre Hospitalier Universitaire, Amiens (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Domonkos Trásy (1) · Dr Cipto Mangunkusumo General Hospital (1) · Enrique Alday Muñoz (1) · Erasme University Hospital (1) · Hospices Civils de Lyon (1)
France (9) · China (3) · Czechia (3) · Egypt (3) · Singapore (2) · Spain (2) · Turkey (Türkiye) (2) · United States (2) · Belgium (1) · Canada (1) · Germany (1) · Hungary (1) · Israel (1) · Lebanon (1) · Sweden (1)
Alparslan Turan, MD (1) · Andrea Kurz (1) · Damien Candela, MD (1) · David Yates, MB ChB (1) · Hairil Rizal Abdullah (1) · Jiaqing Cao (1) · Mehmet A Koc, MD (1) · Murat Urkan, Assoc.Prof. (1)
PMID 12406842, PMID 20156348, PMID 20663275, PMID 22002191, PMID 24510642, PMID 24725276, PMID 25607594, PMID 25930169, PMID 26041437, PMID 26161341, PMID 26313170, PMID 27222707, PMID 27877032, PMID 28767805, PMID 29750699, PMID 33881774, PMID 34754645, PMID 34969004, PMID 38684243, PMID 8265725
2016 (1)