10 completed, 6 unknown, 2 terminated, 1 not yet recruiting. 21 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 21 | Completed 10, Unknown 6, Terminated 2, Not yet recruiting 1, Recruiting 1, Suspended 1 |
| Phase 2 | 7 | Unknown 4, Completed 2, Recruiting 1 |
Follow Language Disorders: new trials by email Literature Review of Language Disorders trials Research Report on Language Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation tDCS - Aphasia, Broca's Aphasia | Phase 2 / Phase 3 | Recruiting | University of South Carolina | 130 | 2026-07-14 | 2026-07-21 |
| EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION ON NAMING IN APHASIC PATIENTS WITH ACUTE ISCHEMIC STROKE Transcranial Direct Current Stimulation - Acute Ischemic Cerebrovascular Disease, Post Stroke Aphasia | Phase 3 | Not yet recruiting | Dr. Ram Manohar Lohia Hospital | 28 | 2026-03-31 | 2026-03-27 |
| Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy Magnetic Spinal Stimulation - Spastic Cerebral Palsy, Dysarthria | Phase 2 / Phase 3 | Unknown | Sociedad Argenttina de Neuromodulación | 20 | 2024-11-18 | 2023-11-21 |
| Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment Precision Medicine Approach, Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises, Standard-of-Care - Mild Cognitive Impairment, Dementia, Mild | Phase 3 | Completed | Alzheimer's Prevention and Reversal Project, Inc. | 73 | 2023-07-31 | 2026-02-18 |
| Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia Donepezil, Intensive-Language Action Therapy, Transcranial direct current stimulation - Aphasia, Stroke | Phase 3 | Completed | University of Malaga | 20 | 2019-01-08 | 2020-11-05 |
| Efficacy and Tolerability of Ecopipam in Adults With Childhood Onset Fluency Disorder (Stuttering). Ecopipam 50mg, Ecopipam 100mg - Stuttering, Adult, Childhood-onset Fluency Disorder | Phase 2 / Phase 3 | Unknown | Gerald Maguire, MD | 10 | 2016-09-01 | 2016-10-26 |
| Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment AM-111 0.4 mg/ml, AM-111 0.8 mg/ml, Placebo - Hearing Loss, Idiopathic Sudden Sensorineural | Phase 3 | Terminated | Auris Medical, Inc. | 56 | 2016-06-01 | 2020-08-07 |
| Use of Local Intraoperative Steroid in MIS TLIF Methylprednisolone, Dexamethasone - Dysphasia | Phase 3 | Completed | Rush University Medical Center | 105 | 2015-11-13 | 2020-11-20 |
| AM-111 in the Treatment of Acute Inner Ear Hearing Loss Placebo, AM-111 0.4 mg/ml, AM-111 0.8 mg/ml - Hearing Loss | Phase 3 | Completed | Auris Medical AG | 256 | 2015-11-01 | 2023-09-14 |
| Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke Patients Transcranial Magnetic Stimulation (TMS-r), Placebo Transcranial Magnetic Stimulation - Aphasia, Broca | Phase 3 | Unknown | Fundación Cardiovascular de Colombia | 100 | 2014-08-01 | 2014-09-16 |
| A Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Tolerability of Asenapine With Flexible Dosing From 5mg to 20mg in Adults With Developmental Stuttering Asenapine - Stuttering | Phase 3 | Suspended | University of California, Irvine | 32 | 2012-09-01 | 2014-05-20 |
| Non-invasive Repetitive Paraorbital Alternating Current Stimulation Therapy for Aphasia rtACS stimulation (Verum condition), placebo condition - Aphasia | Phase 3 | Terminated | University of Magdeburg | 30 | 2010-12-01 | 2013-12-19 |
| A Study to Assess the Efficacy and Safety of Pagoclone for Adults With Stuttering pagoclone, placebo - Stuttering | Phase 2 / Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 321 | 2009-02-01 | 2012-08-28 |
| Improvement of Language Disturbances After Stroke by Intensive Training and Electrical Brain Stimulation anodal tDCS, cathodal tDCS, sham stimulation - Aphasia, Stroke | Phase 2 / Phase 3 | Unknown | University Hospital Muenster | 20 | 2009-01-01 | 2009-01-14 |
| Randomized Clinical Trial of Phonological Interventions Speech Production Intervention, Speech Perception Intervention, Articulation Parent Group - Speech Articulation Disorder, Developmental Articulation Disorder | Phase 2 / Phase 3 | Unknown | McGill University | 96 | 2008-11-01 | 2009-09-23 |
| Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia Melodic Intonation Therapy, Speech-Repetition-Therapy - Aphasia, Stroke | Phase 3 | Completed | Beth Israel Deaconess Medical Center | 30 | 2008-02-01 | 2020-09-21 |
| Augmenting Language Therapy for Aphasia: Levodopa levodopa/carbidopa, Placebo comparator - Nonfluent Aphasia, Stroke | Phase 2 / Phase 3 | Completed | Shirley Ryan AbilityLab | 36 | 2007-10-01 | 2013-12-25 |
| Effectiveness of Early Parent-Based Language Intervention Heidelberg Parent-based Language Intervention HPLI - Language Delay, Developmental Language Disorders | Phase 3 | Unknown | Heidelberg University | 150 | 2003-10-01 | 2008-02-28 |
| A Comparison of Language Intervention Programs Fast ForWord, Computer Assisted Language Intervention, Individual Language Intervention - Language Disorders | Phase 3 | Completed | National Institute on Deafness and Other Communication Disorders (NIDCD) | 216 | 2002-06-01 | 2006-04-24 |
| Treatment of Childhood Social Phobia Social Effectiveness Therapy for Children (SET-C), Fluoxetine, Pill Placebo - Social Phobia | Phase 3 | Completed | University of Central Florida | 139 | 2001-04-01 | 2013-08-01 |
Showing 20 of 21. Sign in to see all of them.
Aphasia (9) · Stroke (7) · Speech Disorders (4) · Aphasia, Broca (3) · Stuttering (3) · Communication Disorders (2) · Deafness (2) · Dyslexia (2) · Ear Diseases (2) · Hearing Disorders (2) · Hearing Loss (2) · Hearing Loss, Sensorineural (2) · Hearing Loss, Unilateral (2) · Otorhinolaryngologic Diseases (2)
Neurobehavioral Manifestations (21) · Pathological Conditions, Signs and Symptoms (21) · Nervous System Diseases (20) · Neurologic Manifestations (20) · Communication Disorders (19) · Signs and Symptoms (19) · Speech Disorders (13) · Brain Diseases (9) · Central Nervous System Diseases (9) · Cardiovascular Diseases (7) · Vascular Diseases (7) · Cerebrovascular Disorders (6) · Mental Disorders (6) · Neurodevelopmental Disorders (5)
Transcranial Direct Current Stimulation (4) · D-JNKI-1 (2) · Dexamethasone (1) · Donepezil (1) · Exercise (1) · Fluoxetine (1) · Hormones (1) · Methylprednisolone (1) · Standard of Care (1) · Transcranial Magnetic Stimulation (1) · Transcutaneous Electric Nerve Stimulation (1) · asenapine (1) · carbidopa, levodopa drug combination (1) · ecopipam (1) · pagoclone (1)
Alzheimer's Prevention and Reversal Project, Inc. (1) · Auris Medical AG (1) · Auris Medical, Inc. (1) · Beth Israel Deaconess Medical Center (1) · Dr. Ram Manohar Lohia Hospital (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Fundación Cardiovascular de Colombia (1) · Gerald Maguire, MD (1) · Heidelberg University (1) · McGill University (1) · National Institute on Deafness and Other Communication Disorders (NIDCD) (1) · Rush University Medical Center (1) · Shirley Ryan AbilityLab (1) · Sociedad Argenttina de Neuromodulación (1)
United States (10) · Germany (3) · Canada (2) · Argentina (1) · Bulgaria (1) · Colombia (1) · India (1) · South Korea (1) · Spain (1)
Agnes Floel, MD (1) · Andrea Norton, BM (1) · Anke Buschmann, MA (1) · Ashish Kumar Duggal, DM (Neurology) (1) · Barbara R. Foorman (1) · Bernhard A Sabel, Prof. Dr. (1) · Dale Bredesen, MD (1) · Federico A Silva, MD,MSc (1) · Gerald Maguire, M.D. (1) · Gottfried Schlaug, MD, PhD (1) · Juan Carlos M Andreani, MD (1) · Kat Toups, MD (1) · Kern Singh, MD (1) · Marcelo L Berthier, MD, PhD (1) · Ronald Gillam, PhD (1)
PMID 10917410, PMID 12849360, PMID 15026214, PMID 15212606, PMID 15328899, PMID 18030084, PMID 19673813, PMID 20013046, PMID 20075648, PMID 21197418, PMID 21391024, PMID 21636820, PMID 24434529, PMID 30497132, PMID 35433325
R01DC008796 (1), R01HD030995 (1), R01MH053703 (1), U01DC022447 (1)