27 completed, 6 unknown, 5 active not recruiting, 4 recruiting. 30 Not applicable, 2 Phase 2, 2 Phase 3, 2 Phase 4, 1 Phase 1.
Follow Hearing Loss, Unilateral: new trials by email Literature Review of Hearing Loss, Unilateral trials Research Report on Hearing Loss, Unilateral
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Cochlear Implantation in Unilateral or Asymmetric Hearing Loss in Children. Cochlear implantation, CROS or BiCROS device fitting, French simplified matrix test (FraSimat) - Unilateral Hearing Loss, Asymmetric Hearing Loss | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 36 | 2026-09-03 | 2026-10-22 |
| Impact of Anatomy-Based Cochlear Implant Programming on Early Performance Programming of cochlear implant audio processor frequency settings - Hearing Loss, Unilateral, Cochlear Implants | Not applicable | Enrolling by invitation | Med-El Corporation | 50 | 2025-11-10 | 2026-03-27 |
| Use of Functional Near-infrared Spectroscopy to Investigate Role of Human Auditory Cortex Plasticity and Multi-sensory Integration on Cochlear Implant Performance After Single-sided Deafness FNIRS Observational - Hearing Loss | Withdrawn | University of Michigan | 2025-05-01 | 2025-06-26 | ||
| Preschool Hearing Screening Otoacoustic Emissions Testing, Pure Tone Audiometry - Hearing Loss, Hearing Disorders in Children | Not applicable | Recruiting | University of California, San Francisco | 13764 | 2023-10-01 | 2026-02-02 |
| Cochlear Implants in Young Children With SSD Cochlear Implant - Single Sided Deafness, Unilateral Deafness | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 60 | 2023-07-07 | 2026-06-26 |
| PRINCE22 System Complete Performance Study Measures of speech intelligibility in a noisy situation with speech from the side and from behind (measured with CC-OLSA Test), Measures of the subjective speech recognition threshold in a noisy situation with speech from the side and from behind (measured with HEISS test), Ability to multitask in the auditory and visual domains in noisy situation with speech from the side and from behind (Multitask test) - Hearing Loss, Bilateral, Hearing Loss, Unilateral | Not applicable | Completed | Sonova AG | 22 | 2022-11-03 | 2023-03-27 |
| Efficacy and Safety of AC102 Compared to Steroids in Adults With Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) AC102 gel, Prednisolone, Placebo Tablets - Hearing Loss, Sensorineural | Phase 2 | Active not recruiting | AudioCure Pharma GmbH | 210 | 2022-10-13 | 2026-01-16 |
| Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness The Cochlear™ Nucleus® Cochlear Implant (CI) System - Hearing Loss, Unilateral, Deafness, Unilateral | Not applicable | Active not recruiting | Cochlear | 60 | 2022-08-19 | 2026-09-30 |
| Evaluation of BiCROS Fitting Benefits Hearing aid fitting - Unilateral Deafness | Not applicable | Completed | Sonova AG | 22 | 2022-07-11 | 2025-06-11 |
| Evaluation of Rehabilitation Results in the Single-sided Deafness With Cochlear Implantation cochlear implant - Unilateral Deafness | Not applicable | Unknown | Chinese PLA General Hospital | 30 | 2022-07-05 | 2023-06-07 |
| Single-Sided Deafness in the Medicare Population MED-EL Cochlear Implant System - Hearing Loss, Unilateral | Not applicable | Completed | Med-El Corporation | 18 | 2022-06-27 | 2026-08-31 |
| iotaSOFT Pediatric Study iotaSOFT Insertion System - Hearing Loss, Sensorineural, Hearing Loss, Bilateral | Not applicable | Completed | iotaMotion, Inc. | 20 | 2022-05-17 | 2026-08-06 |
| Cross-sectional Evaluation of the Subjective Performance and Satisfaction With Ponto Sound Processors Ponto Sound processor - Hearing Loss, Hearing Loss, Conductive | Completed | Oticon Medical | 170 | 2022-04-11 | 2025-08-17 | |
| Clinical Investigation Study of Safety and Performance of the Sentio System. Active transcutaneous bone conduction hearing system - Hearing Loss, Conductive, Hearing Loss, Mixed | Not applicable | Unknown | Oticon Medical | 51 | 2022-01-19 | 2024-04-03 |
| Hear Again, Work Again Cochlear implant - Hearing Loss, Sensorineural, Severe, Hearing Loss, Sensorineural, Bilateral | Unknown | University Hospital, Antwerp | 200 | 2021-12-10 | 2024-12-10 | |
| Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial Cochlear Implant - Asymmetric Hearing Loss, Single-sided Deafness | Not applicable | Active not recruiting | Washington University School of Medicine | 80 | 2021-09-20 | 2026-03-11 |
| Single-Sided Deafness and Asymmetric Hearing Loss MED-EL Cochlear Implant System - Hearing Loss, Unilateral, Hearing Loss, Sensorineural | Not applicable | Active not recruiting | Med-El Corporation | 65 | 2021-02-22 | 2026-10-20 |
| Pilot Study to Evaluate the Long-term Chronic Care of Patients Who Could or do Utilize an Osseointegrated Device (OID) No intervention - Hearing Loss, Conductive, Hearing Loss, Mixed | Recruiting | University of South Florida | 50 | 2021-01-29 | 2026-09-09 | |
| Single-sided Deafness and Cochlear Implantation Cochlear implantation - Hearing Loss, Hearing Loss, Sensorineural | Completed | Johns Hopkins University | 78 | 2020-11-19 | 2023-11-13 | |
| Cochlear Implant Electrostimulation and the Influence on the Vestibular Organ Cochlea Implant - Deafness Unilateral, Deafness, Bilateral | Not applicable | Completed | RWTH Aachen University | 10 | 2020-09-09 | 2021-10-11 |
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Hearing Loss (16) · Hearing Loss, Conductive (11) · Hearing Loss, Sensorineural (9) · Hearing Loss, Mixed Conductive-Sensorineural (8) · Hearing Loss, Bilateral (6) · Deafness (5) · Ear Diseases (3) · Otorhinolaryngologic Diseases (3) · Hearing Disorders (2) · Sensation Disorders (2) · Signs and Symptoms (2) · Speech Disorders (2) · Articulation Disorders (1) · Blindness (1)
Pathological Conditions, Signs and Symptoms (49) · Nervous System Diseases (48) · Neurologic Manifestations (48) · Hearing Disorders (47) · Sensation Disorders (47) · Signs and Symptoms (47) · Ear Diseases (46) · Otorhinolaryngologic Diseases (46) · Hearing Loss (33) · Communication Disorders (3) · Language Disorders (3) · Neurobehavioral Manifestations (3) · Cranial Nerve Diseases (1) · Cranial Nerve Neoplasms (1) · Eye Diseases (1)
Cochlear Implants (8) · Cochlear Implantation (3) · D-JNKI-1 (2) · Drug Delivery Systems (2) · Control Groups (1) · Hearing Aids (1) · Prednisolone (1) · Quality of Life (1) · Stapes Surgery (1)
Oticon Medical (5) · Sonitus Medical Inc (5) · Cochlear (3) · Med-El Corporation (3) · University of North Carolina, Chapel Hill (3) · Sonova AG (2) · University Hospital, Toulouse (2) · University of Miami (2) · Assistance Publique - Hôpitaux de Paris (1) · AudioCure Pharma GmbH (1) · Auris Medical AG (1) · Auris Medical, Inc. (1) · Chinese PLA General Hospital (1) · Hadassah Medical Organization (1) · Henry Ford Health System (1)
United States (28) · Germany (5) · Canada (4) · France (4) · Belgium (3) · Netherlands (3) · Austria (2) · United Kingdom (2) · Bulgaria (1) · China (1) · Czechia (1) · Denmark (1) · Israel (1) · Poland (1) · Serbia (1)
Myrthe Hol, MD, PhD (3) · Michael Murray, MD (2) · Assen Koitschev, Prof. Dr. (1) · Astrid van Wieringen, PhD (1) · Camille Dunn, PhD (1) · Carol A Silverman, PhD, MPH (1) · Charles Syms, MD (1) · Christopher J Linstrom, MD (1) · Daniel Sun, MD (1) · Dylan K Chan, MD, PhD (1) · Emmanuel Mylanus, MD, PhD (1) · Eric W Sargent, MD (1) · George Cire (1) · Gerald Popelka, PhD (1) · Hillary Snapp, AuD (1)
PMID 21221045, PMID 21799455, PMID 25690605, PMID 28375876, PMID 28623107, PMID 33846850, PMID 34415079, PMID 35447955, PMID 36625869, PMID 36879386, PMID 36889821, PMID 38552429, PMID 41250191