9 completed, 3 unknown, 1 withdrawn. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 9, Unknown 3, Withdrawn 1 |
Follow Knee Pain Chronic: new trials by email Literature Review of Knee Pain Chronic trials Research Report on Knee Pain Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty NaCl 0.9%, Dexamethasone 4mg - Osteoarthritis, Knee, Knee Pain Chronic | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2025-09-13 | 2026-05-22 |
| Two-level ESPB in Total Knee Arthroplasty 2 x 20 ml of Ropivacaine 0.2% Injectable Solution, 2 x 20ml of Ropivacaine 0.2% Injectable Solution - Knee Osteoarthritis, Knee Pain Chronic | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-11-07 | 2025-11-25 |
| Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty 0.9% Sodium Chloride Injection, Dexamethasone, Dexmedetomidine - Knee Osteoarthritis, Knee Arthritis | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-08-13 | 2026-03-30 |
| Dexamethasone for iPACK Block With ACB in Total Knee Arthroplasty Ropivacaine, Ropivacaine+Dexamethasone - Knee Osteoarthritis, Knee Pain Chronic | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-08-13 | 2025-07-23 |
| ESPB vs iPACK+ACB in Total Knee Arthroplasty Ropivacaine 0.2% Injectable Solution, control group - Knee Arthritis, Knee Arthropathy | Phase 4 | Unknown | Poznan University of Medical Sciences | 60 | 2024-04-01 | 2024-03-08 |
| NLR and PLR Levels Following IPACK Block in Knee Arthroplasty 0.9% Sodium Chloride Injection, Ropivacaine 0.2% Injectable Solution - Knee Arthropathy, Knee Osteoarthritis | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2024-03-30 | 2025-03-24 |
| Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty Control Test - spinal anesthesia, Ropivacaine 0.2% Injectable Solution ESPB, Ropivacaine 0.2% Injectable Solution iPACK+ACB - Knee Osteoarthritis, Knee Pain Chronic | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-03-30 | 2024-09-26 |
| Can Simplified and More Detailed Instructions Affect Post-Operative Narcotic Consumption Improved Opioid-Tapering Instructions, Clinical Patient Educator - Opioid Use, Opioid Dependence | Phase 4 | Withdrawn | Brigham and Women's Hospital | 2022-06-06 | 2023-02-27 | |
| Phenol Neurolysis of Genicular Nerves for Osteoarthritic Knee Pain 6% aqueous phenol, Isotonic saline - Osteoarthritis, Knee, Knee Pain Chronic | Phase 4 | Unknown | Kessler Foundation | 30 | 2021-11-01 | 2022-03-31 |
| The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement Venlafaxine 37.5 MG, Placebo - Acute Pain, Chronic Pain | Phase 4 | Completed | University of California, San Francisco | 100 | 2021-05-10 | 2025-05-20 |
| Pain Management After Adductor Canal Block for Total Knee Arthroplasty Ropivacaine 0.2% Injectable Solution, 0.9%sodium chloride - Knee Osteoarthritis, Knee Arthritis | Phase 4 | Completed | Poznan University of Medical Sciences | 361 | 2020-06-18 | 2023-10-17 |
| iPACK Block for Total Knee Arthroplasty Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL - Knee Osteoarthritis, Knee Pain Chronic | Phase 4 | Unknown | Poznan University of Medical Sciences | 350 | 2020-06-16 | 2023-10-18 |
| Gabapentin Regimens and Their Effects on Opioid Consumption Gabapentin - Knee Osteoarthritis, Knee Pain Chronic | Phase 4 | Completed | Brigham and Women's Hospital | 77 | 2018-05-15 | 2021-02-18 |
Osteoarthritis, Knee (12) · Opioid-Related Disorders (2) · Acute Pain (1) · Agnosia (1) · Chronic Pain (1) · Neuralgia (1)
Arthritis (12) · Joint Diseases (12) · Musculoskeletal Diseases (12) · Osteoarthritis (12) · Rheumatic Diseases (12) · Chemically-Induced Disorders (2) · Mental Disorders (2) · Narcotic-Related Disorders (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Substance-Related Disorders (2) · Neurobehavioral Manifestations (1) · Neuromuscular Diseases (1)
Ropivacaine (7) · Sodium Chloride (5) · Dexamethasone (2) · Anesthesia, Spinal (1) · Control Groups (1) · Dexmedetomidine (1) · Gabapentin (1) · Phenol (1) · Saline Solution (1) · Venlafaxine Hydrochloride (1)
Poznan University of Medical Sciences (9) · Brigham and Women's Hospital (2) · Kessler Foundation (1) · University of California, San Francisco (1)
Poland (9) · United States (4)
Malgorzata Domagalska, Ph.D. (2) · Malgorzata Reysner, M.D. Ph.D. (2) · Malgorzata Domagalska, M.D. PhD. (1) · Matthias Behrends, MD (1) · Paul So, MD (1) · Wolfgang Fitz, M.D. (1) · Wolfgang Fitz, MD (1)