113 completed, 21 unknown, 10 recruiting, 10 terminated. 58 Phase 4, 30 Phase 3, 29 Phase 2, 19 Not applicable, 17 Phase 1.
Follow this drug Literature Review of Venlafaxine Hydrochloride trials Research Report on Venlafaxine Hydrochloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures - Postsurgical Pain Management, Postsurgical Pain, Chronic | Phase 3 | Not yet recruiting | University of California, San Francisco | 474 | 2026-10-01 | 2026-10-09 |
| The Efficacy and Safety of Pregabalin Combined With Venlafaxine in Patients With Fibromyalgia Pregabalin, Pregabalin with venlafaxine - Fibromyalgia, Pregabalin | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-09-20 | 2026-09-02 |
| Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure Clozapine, Esketamine Nasal Product, Escitalopram - Schizophrenia and Related Disorders, Major Depressive Disorder | Phase 3 | Recruiting | Dr. Inge Winter | 1254 | 2025-04-27 | 2026-01-22 |
| Effect of Exercise on Tapering Antipsychotics in Patients With Psycho-cardiological Disease(EXTRA-study) Moderate-intensity continuous movement and Antipsychotics intervention, Antipsychotics intervention(sertraline, escitalopram, fluoxetine, duloxetine, paroxetine, venlafaxine, and fluvoxamine) - Cardiovascular Diseases (CVD), Depression Anxiety Disorder | Not applicable | Recruiting | Guangdong Provincial People's Hospital | 106 | 2025-04-22 | 2025-06-17 |
| Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder Venlafaxine, Dosulepin - Somatic Symptom Disorder (DSM-V) | Phase 4 | Recruiting | All India Institute of Medical Sciences, Bhubaneswar | 84 | 2025-03-11 | 2025-09-24 |
| The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. Escitalopram, Sertraline, Venlafaxine - Bipolar Depression | Phase 3 | Recruiting | Dr. Inge Winter | 418 | 2025-02-11 | 2025-09-26 |
| Neurobiological and Genomic Predictors of Relapse in Depression Antidepressant Medications - Healthy, Major Depressive Disorder (MDD) | Recruiting | Mehmet Kemal Arikan | 204 | 2025-01-01 | 2026-01-09 | |
| Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea Atomoxetine 80mg combined with oxybutynin 5mg, Venlafaxine 37.5mg, oxybutynin 5mg combined with trazodone 100mg - Obstructive Sleep Apnea of Adult | Phase 4 | Completed | China Medical University Hospital | 45 | 2024-11-05 | 2026-04-23 |
| REDucing Hot FLASHes in Women Using Endocrine Therapy. Oxybutynin, Venlafaxine - Breast Cancer, Hot Flash Due to Medication | Phase 3 | Recruiting | Reinier de Graaf Groep | 260 | 2024-10-03 | 2025-02-04 |
| Mood Disorders in Head and Neck Cancer Patients Venlafaxine - Depressive Disorder, Head and Neck Cancer | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2024-01-05 | 2025-02-04 | |
| A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats Fezolinetant, Paroxetine, Citalopram - Hot Flashes | Completed | Astellas Pharma Global Development, Inc. | 999 | 2023-11-15 | 2026-06-05 | |
| Venlafaxine for the Prevention of Depression in Patients With Head and Neck Cancer Venlafaxine, Placebo - Head and Neck Cancer, Depression | Phase 2 | Withdrawn | Vanderbilt University Medical Center | 2023-08-01 | 2024-01-18 | |
| Venlafaxine for Postoperative Pain of Laparoscopic Cholecystectomy Venlafaxine, Placebo - Laparoscopic Cholecystectomy | Phase 1 / Phase 2 | Unknown | Mansoura University | 60 | 2023-05-30 | 2023-06-01 |
| Preventive Approach Using Venlafaxine Venlafaxine 75 MG, Gabapentin 400 mg - Peripheral Neuropathy Due to Chemotherapy | Phase 4 | Unknown | Mit Ghamr Oncology Center | 60 | 2023-05-01 | 2023-05-25 |
| Comparative Responses to 15 Different Antidepressants in Major Depressive Disorder Antidepressant - Major Depressive Disorder | Completed | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | 73336 | 2022-10-01 | 2023-08-18 | |
| Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea Escitalopram, Paroxetine, Fluoxetine - Major Depression | Completed | Pfizer | 370212 | 2022-07-04 | 2024-12-09 | |
| A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR - Posttraumatic Stress Disorder | Phase 4 | Active not recruiting | University of Pennsylvania | 304 | 2022-05-25 | 2026-06-09 |
| The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN) Venlafaxine - Major Depressive Disorder, Bipolar Affective Disorder, Currently Depressed, Moderate | Phase 4 | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 30 | 2022-03-01 | 2023-11-14 |
| Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities Vortioxetine, Venlafaxine - Major Depressive Disorder | Phase 3 | Unknown | Scotmann Pharmaceuticals | 500 | 2022-02-01 | 2021-11-18 |
| The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement Venlafaxine 37.5 MG, Placebo - Acute Pain, Chronic Pain | Phase 4 | Completed | University of California, San Francisco | 100 | 2021-05-10 | 2025-05-20 |
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Depression (58) · Depressive Disorder, Major (46) · Depressive Disorder (11) · Anxiety Disorders (10) · Bipolar Disorder (10) · Hot Flashes (8) · Pain (7) · Mood Disorders (5) · Stress Disorders, Post-Traumatic (5) · Breast Neoplasms (4) · Cognitive Dysfunction (4) · Dysthymic Disorder (4) · Alzheimer Disease (3) · Fibromyalgia (3) · Obsessive-Compulsive Disorder (3)
Wyeth is now a wholly owned subsidiary of Pfizer (7) · New York State Psychiatric Institute (6) · Teva Pharmaceuticals USA (5) · University of California, Los Angeles (5) · University of Pittsburgh (5) · Massachusetts General Hospital (4) · Mayo Clinic (4) · University of Pennsylvania (4) · Centre for Addiction and Mental Health (3) · Duke University (3) · University of Washington (3) · All India Institute of Medical Sciences, Bhubaneswar (2) · Dr. Inge Winter (2) · Eli Lilly and Company (2) · Icahn School of Medicine at Mount Sinai (2)
United States (69) · Canada (22) · China (11) · Germany (10) · France (9) · Australia (4) · India (4) · Poland (4) · Romania (4) · South Korea (4) · Sweden (4) · Taiwan (4) · Austria (3) · Belgium (3) · Brazil (3)
Benoit Girard, M.D. (4) · Ajay Wasan, MD, MSc (1) · Albert Pinhasov, PhD (1) · Anatoly Kreinin, MD, PhD (1) · Andrea Allen, PhD (1) · Andrew Bishara, MD (1) · Andrew F Leuchter, MDe (1) · Andrew F. Leuchter, MD (1) · Andrew Leuchter, MD (1) · Anthony Chiodo, M.D. (1) · Anthony Harris, MD (1) · Anurag Singh (1)
PMID 18635722, PMID 21102344, PMID 22249355, PMID 30358242, PMID 31846575, PMID 41401709, PMID 10568846, PMID 11032384, PMID 11166482, PMID 11522260, PMID 11689978, PMID 11888224, PMID 12053639, PMID 16505409, PMID 17173978, PMID 17227907, PMID 17414743, PMID 17474806, PMID 17559726, PMID 18174510, PMID 18227745, PMID 18251622, PMID 18314433, PMID 19081579, PMID 19182688, PMID 19183470, PMID 19210951, PMID 19223438, PMID 19358791, PMID 19472307, PMID 19485586, PMID 19574030, PMID 19653973, PMID 19730273, PMID 19730274, PMID 19858762, PMID 19963436, PMID 19968380, PMID 20008943, PMID 20080793, PMID 20187947, PMID 20478877, PMID 21135327, PMID 21170955, PMID 21192150, PMID 21208417, PMID 21208583, PMID 21255766, PMID 21269443, PMID 21334569
2005 (1), 2008 (1), 2023 (1), P50DA009236 (1), R01AA013727 (1), R01AG040093 (1), R01AT002479 (1), R01DA015451 (1), R01MH043832 (1), R01MH055121 (1), R01MH060353 (1), R01MH061410 (1), R01MH061609 (1), R01MH065963 (1), R01MH070919 (1)