20 recruiting, 20 unknown, 11 completed, 2 enrolling by invitation. 26 Not applicable, 3 Phase 1, 2 Phase 3, 1 Phase 2.
Follow Moyamoya Disease: new trials by email Literature Review of Moyamoya Disease trials Research Report on Moyamoya Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multicenter, Prospective, Double-blind, Randomized Controlled Study on the Efficacy and Safety of Ischemic Preconditioning Therapy Versus Optimal Medical Therapy in Reducing the Recurrence of Ischemic Events in Symptomatic Moyamoya Disease remote ischemic conditioning (RIC), Control - Moya Moya Disease, Moyamoya Syndrome | Not applicable | Recruiting | Beijing Tiantan Hospital | 256 | 2026-10-10 | 2026-10-22 |
| Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project) AI, healthy dialogue - Stroke, Moyamoya Disease | Not applicable | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 20 | 2026-10-01 | 2026-08-28 |
| Evaluating Antiplatelet and Physical Therapy for Slowing Progression in Mild Moyamoya Disease. aspirin treatment, Aspirin placebo, Remote Ischemic Conditioning - Moyamoya Disease, Moyamoya Syndrome | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 724 | 2026-07-15 | 2026-08-13 |
| Application of Extended Reality (XR)-Assisted Computed Tomography (CT)-Guided Localization in Extracranial-intracranial (EC-IC) Bypass Surgery NTU OpVerse surgical simulation platform - Chronic Cerebral Ischemia, Moyamoya Disease | Recruiting | National Taiwan University Hospital | 30 | 2026-06-26 | 2026-07-23 | |
| Remimazolam Consumption: TCI vs. Manual Infusion Target-Controlled Infusion (TCI) of Remimazolam, Manual Infusion of Remimazolam - Moyamoya Disease | Not applicable | Recruiting | Seoul National University Hospital | 58 | 2026-02-04 | 2026-04-23 |
| 5T MRI and Metabolomics-Based Hemorrhage Risk Prediction in Moyamoya Disease Moyamoya Disease, Intracranial Hemorrhages | Recruiting | Beijing Hospital | 500 | 2026-02-01 | 2026-08-24 | |
| Chinese Herbal Therapy (Qiqi Shengmai Formula) for Moyamoya Vasculopathy: The CHIMES Trial Traditional Chinese Medicine (TCM) Treatment, Conventional medical treatment, TCM Placebo - Moyamoya Disease, Moyamoya Syndrome | Phase 1 | Not yet recruiting | Fudan University | 66 | 2025-12-30 | 2025-12-22 |
| Cardiac Index-Guided Intraoperative Hemodynamic Management in Pediatric Moyamoya Surgery Cardiac Index-Guided Hemodynamic Management, Blood Pressure-Guided Standard Hemodynamic Management - Moyamoya Disease | Not applicable | Recruiting | Seoul National University Hospital | 94 | 2025-12-02 | 2025-12-26 |
| The Symani Restore Study Symani Surgical System - Moyamoya Disease | Not applicable | Recruiting | Jacobs institute | 15 | 2025-09-20 | 2025-10-16 |
| Cognitive-Motor Incorporated Training and Its Relations in Cerebrovascular Diseases With Cognitive and Motor Impairments MCIT program, Motor training program - Moyamoya Disease, Healthy | Not applicable | Recruiting | National Taiwan University Hospital | 210 | 2025-06-23 | 2026-08-28 |
| Treatment of Moyamoya Disease With iPSC-derived Exosomes iPSC-EVs - Moyamoya Disease | Phase 1 | Recruiting | Huaqiu Zhang | 9 | 2025-05-26 | 2025-10-01 |
| Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease Standard of Care - Moya Moya Disease | Recruiting | Stanford University | 88 | 2025-05-21 | 2025-05-28 | |
| Study on the Mechanism of Cognitive Impairment in Patients with Moyamoya Disease Revascularization - Moyamoya Disease | Recruiting | Beijing Tiantan Hospital | 360 | 2024-12-16 | 2025-02-18 | |
| Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya Disease Revascularization/Conservative management - Moyamoya Disease | Recruiting | Beijing Tiantan Hospital | 330 | 2024-12-15 | 2025-02-10 | |
| Family-Based Moyamoya Susceptibility and Early Detection 5T High-Resolution MRI - Moyamoya Disease | Recruiting | Beijing Tiantan Hospital | 700 | 2024-11-12 | 2026-04-08 | |
| A Study of Cerebral Perfusion With tDCS in Chronic Hypoperfusion Soterix® 4x1HD-TDCS, Soterix® 1x1 tDCS, Cognitive training program - Moyamoya Syndrome, Moyamoya Disease | Not applicable | Completed | Mayo Clinic | 7 | 2024-10-24 | 2026-08-05 |
| Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization Therapy RIC group, Medication group - Moyamoya Disease, Pediatric | Not applicable | Unknown | Capital Medical University | 42 | 2024-09-10 | 2024-09-19 |
| Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients MRI, H2 15O PET/CT, Biosampling - Moyamoya Disease, Moyamoya | Not applicable | Recruiting | University Hospital Tuebingen | 50 | 2024-07-01 | 2024-09-26 |
| Functional Magnetic Resonance-Based Observations of Brain Networks in Moyamoya Disease Patients Under Anesthesia Moyamoya Disease | Recruiting | Beijing Tiantan Hospital | 48 | 2023-10-24 | 2025-02-13 | |
| Prognostic Prediction Model in Patients With Moyamoya Disease Undergoing Revascularization Surgery Moyamoya Disease | Unknown | Beijing Tiantan Hospital | 350 | 2023-10-01 | 2023-09-25 |
Showing 20 of 59. Sign in to see all of them.
Stroke (10) · Ischemic Stroke (4) · Cerebrovascular Disorders (3) · Cognitive Dysfunction (3) · Ischemic Attack, Transient (3) · Subarachnoid Hemorrhage (3) · CADASIL (2) · Cerebral Hemorrhage (2) · Depression (2) · Intracranial Aneurysm (2) · Muscle Spasticity (2) · 3-Methylglutaconic Aciduria, Type V (1) · Achalasia Addisonianism Alacrimia syndrome (1) · Acrodysostosis (1)
Brain Diseases (59) · Cardiovascular Diseases (59) · Carotid Artery Diseases (59) · Central Nervous System Diseases (59) · Cerebral Arterial Diseases (59) · Intracranial Arterial Diseases (59) · Nervous System Diseases (59) · Vascular Diseases (59) · Arterial Occlusive Diseases (58) · Cerebrovascular Disorders (56) · Mental Disorders (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7) · Stroke (6) · Brain Ischemia (5)
Conservative Treatment (4) · Erythropoietin (2) · Saline Solution (2) · 3-n-butylphthalide (1) · Aspirin (1) · Cerebral Revascularization (1) · Magnetic Resonance Imaging (1) · Medicine, Chinese Traditional (1) · Sevoflurane (1) · Spectroscopy, Near-Infrared (1) · Standard of Care (1) · Surveys and Questionnaires (1) · Therapeutics (1) · Transcobalamins (1) · Transcranial Magnetic Stimulation (1)
Beijing Tiantan Hospital (13) · Seoul National University Hospital (6) · Capital Medical University (4) · Huashan Hospital (4) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (3) · Affiliated Hospital to Academy of Military Medical Sciences (2) · Assistance Publique - Hôpitaux de Paris (2) · Chinese PLA General Hospital (2) · Great Ormond Street Hospital for Children NHS Foundation Trust (2) · Mayo Clinic (2) · National Taiwan University Hospital (2) · Stanford University (2) · Ajou University School of Medicine (1) · Beijing Hospital (1) · Cedars-Sinai Medical Center (1)
China (29) · United States (8) · South Korea (7) · France (3) · Italy (3) · Taiwan (2) · United Kingdom (2) · Australia (1) · Germany (1)
Yuanli Zhao, MD (2) · Yuxiang Gu, MD,PhD (2) · Colin Derdeyn, MD (1) · Dong Xu, MD (1) · Dong Zhang, MD (1) · Eugene Kim, MD (1) · Greg Zaharchuk (1) · Hao Wang, MD (1) · Hee Pyung Park, MD PhD (1) · Hee Pyung Park, MD, PhD (1) · Heze Han, MD (1) · Huaqiu Zhang (1) · James Meschia, MD (1)
PMID 19021845, PMID 23394336, PMID 28283605, PMID 29626135, PMID 30361434, PMID 30688272, PMID 30898819, PMID 34000646, PMID 35972776, PMID 36367058, PMID 36645250, PMID 37386744, PMID 37576009, PMID 37620982, PMID 38228908, PMID 40079509, PMID 41093253, PMID 41205868, PMID 42219999, PMID 42532457
R01NS051631 (1), R01NS133101 (1)