19 completed, 11 recruiting, 11 unknown, 4 not yet recruiting. 15 Not applicable, 3 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 8, Recruiting 3, Unknown 3, Not yet recruiting 1 |
| Phase 2 | 3 | Recruiting 2, Unknown 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow Intracranial Arteriovenous Malformations: new trials by email Literature Review of Intracranial Arteriovenous Malformations trials Research Report on Intracranial Arteriovenous Malformations
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase II Trial of Fetal Embolization for Vein of Galen Malformation Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils - Vein of Galen Malformations | Not applicable | Recruiting | Darren Orbach | 20 | 2026-07-20 | 2026-07-23 |
| Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases | Not yet recruiting | Duan Chuanzhi | 630 | 2026-02-01 | 2026-01-20 | |
| Postmarket Study of Tarvos Microguidewire in Neurovascular Interventional Surgery Tarvos Microguidewire - Intracranial Aneurysm, AVM - Cerebral Arteriovenous Malformation | Completed | Keuro MedTech | 121 | 2026-01-29 | 2026-04-02 | |
| Efficacy and Safety of Anti-angiogenic Therapy With IV Bevacizumab in Patients With Symptomatic Cerebral Arteriovenous Malformations Bevacizumab, Placebo - Cerebral AV Malformation | Phase 2 / Phase 3 | Recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 54 | 2026-01-16 | 2026-01-22 |
| In Situ Injection of Anti-angiogenics in Patients With Brain Arteriovenous Malformations Not Eligible for Exclusion Treatment Single in situ intra-arterial injection of bevacizumab - Brain Arteriovenous Malformations | Phase 1 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 20 | 2025-10-01 | 2025-07-20 |
| Liquid Biopsies for Detecting Somatic Mutations in Sporadic Cerebral Arteriovenous Malformations. Search for activating somatic genetic mutations - Cerebral Arteriovenous Malformations | Not yet recruiting | University Hospital, Rouen | 16 | 2025-09-01 | 2025-09-08 | |
| Clinical Trial for the Validation of AR Based Neuronavigation System AR-based navigation - Brain Neoplasms, Cerebral Aneurysm | Not applicable | Not yet recruiting | Seoul National University Hospital | 80 | 2025-05-01 | 2024-12-03 |
| Clinical Study on Emergency Treatment of Cerebral Arteriovenous Malformation Bleeding Arteriovenous Malformation, Bleeding | Recruiting | Beijing Tiantan Hospital | 162 | 2025-04-01 | 2025-08-12 | |
| Vein of Galen Aneurysm embolization therapy - Vein of Galen Malformation | Completed | Erasme University Hospital | 19 | 2024-10-01 | 2025-05-21 | |
| Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping Endovascular treatment - Intracranial Aneurysm, Arteriovenous Malformations, Cerebral | Recruiting | University Hospital, Ghent | 500 | 2024-08-13 | 2026-05-13 | |
| Efficacy and Safety of the Liquid Embolic System (Tonbridge) for Endovascular Treatment of Cerebrovascular Malformations Liquid Embolic System (Tonbridge), Onyx Liquid Embolic System (Medtronic) - Intracranial Arteriovenous Malformations | Not applicable | Recruiting | Ton-Bridge Medical Tech. Co., Ltd | 170 | 2024-06-27 | 2024-09-19 |
| Comprehensive HHT Outcomes Registry of the United States (CHORUS) Hereditary Hemorrhagic Telangiectasia, Arteriovenous Malformations | Recruiting | Cure HHT | 10000 | 2023-11-13 | 2026-07-17 | |
| Fetal Treatment of Galenic Malformations Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils - Vein of Galen Malformations | Not applicable | Completed | Darren Orbach | 7 | 2022-09-30 | 2026-10-21 |
| ACtive Catheterization for EndovaScular TreatmentS GECKO Active Guidewire - Unruptured Intracranial Aneurysm, Arteriovenous Cerebral Malformations | Not applicable | Completed | Basecamp Vascular | 10 | 2022-06-27 | 2022-11-03 |
| Hereditary Hemorrhagic Telangiectasia and Neurovascular Manifestations, in the Danish HHT Database Brain MRI - Telangiectasia, Hereditary Hemorrhagic, Intracranial Arteriovenous Malformations | Active not recruiting | Odense University Hospital | 300 | 2022-04-01 | 2025-03-30 | |
| Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN) Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis - Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial | Not applicable | Completed | Erasme University Hospital | 22 | 2022-03-01 | 2024-02-21 |
| Non-adhesive Liquid Embolic System in the Embolization of Cerebral Arteriovenous Malformations embolism - Intracranial Arteriovenous Malformations | Not applicable | Unknown | Suzhou Hengruihongyuan Medical Technology Co. LTD | 116 | 2021-12-02 | 2022-05-06 |
| Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform BALT medical devices - Intracranial Aneurysm, Brain Arterial Disease | Recruiting | Balt Extrusion | 10000 | 2021-07-12 | 2025-09-18 | |
| Cerebral Vascular Malformations: From Multimodal Imaging, to Endovascular, Surgical or Combined Treatment Endovascular embolization or surgery - AVM (Arteriovenous Malformation) Intracranial | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 200 | 2021-06-24 | 2023-02-15 | |
| Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT) Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT) - Diabetic Foot Ulcer, Coronary Artery Disease | Not applicable | Unknown | Hospices Civils de Lyon | 339 | 2021-01-29 | 2024-04-04 |
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Intracranial Aneurysm (10) · Arteriovenous Malformations (6) · Brain Neoplasms (5) · Arteriovenous Fistula (4) · Cerebral Hemorrhage (4) · Vein of Galen Malformations (4) · Stroke (3) · Subarachnoid Hemorrhage (3) · Telangiectasia, Hereditary Hemorrhagic (3) · Carotid Stenosis (2) · Congenital Abnormalities (2) · Intracranial Arterial Diseases (2) · Intracranial Hemorrhages (2) · Ischemic Stroke (2)
Central Nervous System Diseases (47) · Cerebrovascular Disorders (47) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (47) · Nervous System Diseases (47) · Nervous System Malformations (47) · Brain Diseases (46) · Cardiovascular Abnormalities (46) · Cardiovascular Diseases (46) · Central Nervous System Vascular Malformations (46) · Vascular Diseases (46) · Congenital Abnormalities (45) · Intracranial Arterial Diseases (45) · Vascular Malformations (45) · Arteriovenous Malformations (41) · Pathological Conditions, Signs and Symptoms (13)
Bevacizumab (1) · Embolic Protection Devices (1) · Embolization, Therapeutic (1) · Indocyanine Green (1) · Lovastatin (1) · Magnetic Resonance Imaging (1) · Practice Management, Medical (1) · Radiosurgery (1) · Single Person (1) · Spectroscopy, Near-Infrared (1) · Surgical Procedures, Operative (1)
Beijing Tiantan Hospital (6) · Darren Orbach (2) · Erasme University Hospital (2) · Fondation Ophtalmologique Adolphe de Rothschild (2) · University Hospital, Antwerp (2) · Alejandro Berenstein (1) · Assistance Publique - Hôpitaux de Paris (1) · Balt Extrusion (1) · Basecamp Vascular (1) · Bispebjerg Hospital (1) · Cedars-Sinai Medical Center (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Columbia University (1) · Cure HHT (1) · Dr. Yong Cao (1)
China (13) · France (12) · United States (10) · Belgium (7) · Germany (5) · Denmark (4) · Canada (3) · Italy (3) · Spain (3) · Austria (2) · Netherlands (2) · South Korea (2) · United Kingdom (2) · Australia (1) · Brazil (1)
Shuo Wang, MD (3) · Darren Orbach, MD PhD (2) · Tomas Menovsky, MD, PhD (2) · Vera Saldien, MD (2) · Adrien Guenego, MD (1) · Ahmed Otokiti, MBBS (1) · Alan J. Moskowitz, MD (1) · Alejandro Berenstein, M.D (1) · Alejandro Berenstein, MD (1) · Cassi Friday, PhD (1) · Christian Stapf, MD (1) · Christophe Cognard, Prof. Dr. (1) · Chuanzhi Duan, MD (1) · Chul-Kee Park, MD, PhD (1) · Claudia S. Moy, PhD (1)
PMID 31379715, PMID 17962585, PMID 19953376, PMID 22826821, PMID 24268105, PMID 25341453, PMID 26089327, PMID 26093360, PMID 26451020, PMID 27367242, PMID 28132013, PMID 28526977, PMID 28642352, PMID 28878048, PMID 29547081, PMID 30843441, PMID 32197246, PMID 32562682, PMID 35613814, PMID 37139817, PMID 39043982, PMID 40143818, PMID 40788723, PMID 41843464, PMID 41962956, PMID 42399096, PMID 42532457
2023 (1), R01CA238783 (1), U01NS051483 (1), U01NS051566 (1), U54NS065705 (1)