8 completed, 3 terminated, 3 unknown, 1 not yet recruiting. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 8, Terminated 3, Unknown 3, Not yet recruiting 1 |
Follow Ileus: new trials by email Literature Review of Ileus trials Research Report on Ileus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Preoperative Intrathecal Dexamethasone Versus Dexmedetomidine on Paralytic Ileus After Major Abdominal Surgery Dexamethasone, Dexmedetomidine - Paralytic Ileus | Phase 4 | Not yet recruiting | Assiut University | 60 | 2025-01-01 | 2024-12-30 |
| The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction Neostigmine / Glycopyrrolate, Sugammadex - Hernia, Ventral, Ileus | Phase 4 | Completed | Clayton Petro | 184 | 2024-01-15 | 2025-11-21 |
| Neostigmine Route for Acute Colonic Pseudo Obstruction Neostigmine - Ogilvie Syndrome | Phase 4 | Unknown | University of Southern California | 90 | 2022-02-04 | 2023-08-25 |
| Preoperative High-dose Dexamethasone and Emergency Laparotomy Dexamethasone 1 mg/kg, Physiologic saline - Intestinal Obstruction and Ileus, Perforated Viscus | Phase 4 | Completed | Mirjana Cihoric | 120 | 2021-03-01 | 2022-12-14 |
| Alvimopan as a Rescue Treatment of Postoperative Ileus Alvimopan - Ileus, Gastrointestinal Dysfunction | Phase 4 | Completed | Scott Steele | 65 | 2020-08-01 | 2025-08-20 |
| The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus Naloxone - Ileus, Fusion of Spine | Phase 4 | Terminated | Loyola University | 53 | 2017-09-20 | 2024-07-01 |
| Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Acetaminophen, Gabapentin, Orphenadrine - Colon Cancer, Colon Diverticulosis | Phase 4 | Unknown | University of Illinois College of Medicine at Peoria | 80 | 2017-01-01 | 2017-03-20 |
| Laparoscopic Cholecystectomy: General Anesthesia With Opioid Versus General Opioid Free Anesthesia dexter ketamine, Lidocaine Hydrochloride, Fentanyl Hydrochloride - Pain, Postoperative, Anesthesia Complication | Phase 4 | Unknown | Federal University of São Paulo | 40 | 2016-11-01 | 2016-11-04 |
| Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery Simethicone, Oral Suspending Vehicle - Postoperative Ileus, Ileus | Phase 4 | Completed | McMaster University | 100 | 2014-10-01 | 2015-12-04 |
| Intravenous Nutrition in Hospitalized Patients: Comparison of Two Oils Intralipid, ClinOleic - Obstruction, Cancer | Phase 4 | Completed | Johane Allard | 303 | 2013-07-01 | 2025-02-03 |
| Nicotine Gum Recovery After Colorectal Surgery Nicotine gum, Regular chewing gum - Post-operative Ileus | Phase 4 | Terminated | The Cleveland Clinic | 4 | 2012-08-01 | 2017-08-22 |
| Effect of Ketamine on Postoperative Clinical Outcomes Placebo, Ketamine high-dose, Ketamine low-dose - Colorectal Surgery | Phase 4 | Terminated | Cedars-Sinai Medical Center | 21 | 2011-05-01 | 2022-03-02 |
| A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy Alvimopan, Placebo - Postoperative Ileus | Phase 4 | Completed | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 280 | 2009-03-01 | 2016-01-08 |
| Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery Docusate natrium and sorbitol, Bisacodyl - Constipation, Ileus | Phase 4 | Completed | Oslo University Hospital | 45 | 2007-12-01 | 2013-06-18 |
| A New Approach of Neostigmine in Unavoidable Post Operative Ileus Neostigmine, Saline - Ileus | Phase 4 | Completed | Baqiyatallah Medical Sciences University | 3 | 2007-08-01 | 2008-05-13 |
Constipation (3) · Agnosia (2) · Pain, Postoperative (2) · Sepsis (2) · Abdominal Pain (1) · Bites and Stings (1) · Colonic Neoplasms (1) · Colonic Pseudo-Obstruction (1) · Diverticulitis, Colonic (1) · Diverticulosis, Colonic (1) · Flatulence (1) · Hernia, Ventral (1) · Hyperphagia (1) · Infections (1)
Digestive System Diseases (15) · Gastrointestinal Diseases (15) · Intestinal Diseases (15) · Intestinal Obstruction (14) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (6) · Signs and Symptoms, Digestive (6) · Pathologic Processes (5) · Neurologic Manifestations (4) · Pain (3) · Colonic Diseases (2) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2)
Ketamine (3) · Neostigmine (3) · Bupivacaine (2) · Dexamethasone (2) · Fentanyl (2) · Lidocaine (2) · alvimopan (2) · Acetaminophen (1) · Bisacodyl (1) · ClinOleic (1) · Clonidine (1) · Dexmedetomidine (1) · Excipients (1) · Gabapentin (1) · Glycopyrrolate (1)
Assiut University (1) · Baqiyatallah Medical Sciences University (1) · Cedars-Sinai Medical Center (1) · Clayton Petro (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Federal University of São Paulo (1) · Johane Allard (1) · Loyola University (1) · McMaster University (1) · Mirjana Cihoric (1) · Oslo University Hospital (1) · Scott Steele (1) · The Cleveland Clinic (1) · University of Illinois College of Medicine at Peoria (1) · University of Southern California (1)
United States (8) · Canada (2) · Brazil (1) · Denmark (1) · Iran (1) · Norway (1)
Cagla Eskicioglu, MD, MSc (1) · Clayton C Petro, MD (1) · Conor Delaney, MD, PhD (1) · Ida T Bjork, MNSc, PhD, (1) · Johane P Allard, MD, FRCPC (1) · Lee Techner, DPM (1) · Meghan Lewis, MD (1) · Nicolai Bang Foss, Professor (1) · Roya Yumul, MD PhD (1) · Roya Yumul, MD., PhD (1) · Russell Nockels, MD (1) · S.Ahmad Fanaei, M.D. (1) · S.Ali Ziaee, M.D. (1) · Shawn S Forbes, MD, MSc (1)
PMID 10403850, PMID 17959952, PMID 19135997, PMID 19209273, PMID 19535182, PMID 24630419, PMID 39028763