25 completed, 11 unknown, 2 not yet recruiting, 2 recruiting. 22 Not applicable, 3 Phase 3, 2 Phase 1, 2 Phase 2, 2 Phase 4.
Follow Hyperventilation: new trials by email Literature Review of Hyperventilation trials Research Report on Hyperventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hyperventilation Effects on Bodily Self-Consciousness Voluntary hyperventilation (guided paced breathing), Normal spontaneous breathing (within-subject control), Synchronous respiratory-visual VR feedback - Bodily Self-Consciousness, Interoception | Not applicable | Not yet recruiting | University of Fribourg | 35 | 2026-09-01 | 2026-08-18 |
| Optimizing Liver MRI Using Breath-Holding With and Without Oxygen Breath-hold conditions - MRI, MRI Image Enhancement | Not applicable | Recruiting | University of California, San Francisco | 10 | 2025-12-01 | 2026-04-13 |
| Voluntary Isocapnic Hyperpnea in Hypoxia to Mitigate Acute Mountain Sickness VIH - Acute Mountain Sickness | Not applicable | Active not recruiting | Institute of Sport - National Research Institute, Poland | 20 | 2025-06-01 | 2025-08-20 |
| Investigation of the Relationship Between Dysfunctional Breathing and Physical Fitness Parameters in Healty Adults Dysfunctional Breathing | Not yet recruiting | Elif Tunç | 38 | 2025-05-15 | 2025-04-24 | |
| To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU. Placebo drug ( normal saline ), neostigmine (reversal agent) - Tachycardia, Hypertension | Phase 1 / Phase 2 | Completed | Ziauddin University | 100 | 2025-03-12 | 2025-07-31 |
| Dysfunctional Breathing in Post COVID-19 Condition. Post COVID-19 Condition (PCC), Dysfunctional Breathing | Recruiting | Karolinska Institutet | 200 | 2025-01-15 | 2025-02-14 | |
| Detecting Absence Seizures Using Hyperventilation and Eye Movement Recordings Eysz Hyperventilation Recorder - Absence Epilepsy, Childhood, Absence Seizures | Completed | Eysz, Inc. | 65 | 2023-12-01 | 2025-10-15 | |
| Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on Memory Nose-breathing training, Mouth-breathing training - Hypoventilation, Hyperventilation | Not applicable | Unknown | Universität des Saarlandes | 75 | 2023-06-03 | 2024-04-17 |
| Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia Chemoreflex Testing, Baroreflex testing, Orthostatic stress testing - Postural Orthostatic Tachycardia Syndrome, Hypocapnia | Not applicable | Unknown | New York Medical College | 30 | 2022-09-23 | 2023-06-28 |
| The Use of a Monitoring Device by General Practitioners During Out-of-hours Care Use of the PICO(TM) monitoring device - Emergencies, Heart Failure | Not applicable | Unknown | KU Leuven | 866 | 2022-05-01 | 2022-02-03 |
| Effects of Chest Physiotherapy in Hyperventilation Syndrome chest physiotherapy - Hyperventilation | Completed | Centre Hospitalier des Pays de Morlaix | 46 | 2021-10-01 | 2023-08-31 | |
| Drug Intervention of Spontaneous Hyperventilation in Patients With Aneurysmal Subarachnoid Hemorrhage Remifentanil Injection [Ultiva] - Hyperventilation, Aneurysmal Subarachnoid Hemorrhage | Not applicable | Unknown | Capital Medical University | 30 | 2021-06-01 | 2021-06-25 |
| Treatment of Spontaneous Hyperventilation With Remifentanil in Traumatic Brain Injury Patients Remifentanil Injection - Hyperventilation, Traumatic Brain Injury | Not applicable | Unknown | Capital Medical University | 30 | 2021-06-01 | 2021-07-29 |
| The Effect of Different Ventilation Strategies on Cerebral Oxygenation Using Near Infrared Spectroscopy (NIRS) in Pediatrics Undergoing Posterior Fossa Tumor Surgery cerebral oximetry - Infratentorial Neoplasms, Hyperventilation | Not applicable | Completed | Kasr El Aini Hospital | 42 | 2020-01-01 | 2022-03-07 |
| Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in isolated plasma., In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in whole blood, Biomolecular analysis of plasma proteins. - Sepsis, Septic Shock | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 90 | 2019-06-03 | 2019-06-04 | |
| Hyperventilation and Oxygenation to Prolong Breath Hold in Breast Cancer Irradiation Treatment Optiflow/Ventilator - Breast Cancer | Not applicable | Completed | University Hospital, Ghent | 40 | 2019-03-15 | 2023-01-04 |
| Prevalence of the Hyperventilation Syndrome in Pulmonary Arterial Hypertension Hyperventilation test - Pulmonary Arterial Hypertension | Not applicable | Unknown | Assistance Publique - Hôpitaux de Paris | 50 | 2019-01-14 | 2019-01-18 |
| Evaluation of Respiratory Function in Fibromyalgia Fibromyalgia, Respiratory Alkalosis and Metabolic Acidosis | Completed | Uppsala University | 90 | 2018-06-28 | 2022-03-21 | |
| Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics. Acute Hyperventilation, Chronic hyperventilation, Effects of anticholinergic medication - Hyperventilation, Larynx | Completed | Monash Medical Centre | 24 | 2018-06-01 | 2025-05-08 | |
| Cerebrospinal Acid-base in Pregnant and Non-pregnant Fertile Women Acid - Base characterization - Acid-Base Imbalance, Respiratory Alkalosis | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 40 | 2018-04-13 | 2018-04-17 |
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Alkalosis, Respiratory (8) · Respiratory Aspiration (6) · Acid-Base Imbalance (3) · Acidosis, Respiratory (3) · Apnea (3) · Altitude Sickness (2) · Anxiety Disorders (2) · Asthma (2) · Coronary Artery Disease (2) · Dyspnea (2) · Fibromyalgia (2) · Heart Arrest (2) · Hypocapnia (2) · Hypoventilation (2)
Respiration Disorders (43) · Respiratory Tract Diseases (43) · Pathological Conditions, Signs and Symptoms (41) · Signs and Symptoms (39) · Signs and Symptoms, Respiratory (36) · Pathologic Processes (11) · Nervous System Diseases (10) · Alkalosis (8) · Metabolic Diseases (8) · Nutritional and Metabolic Diseases (8) · Cardiovascular Diseases (6) · Acid-Base Imbalance (5) · Heart Diseases (5) · Respiratory Insufficiency (5)
Injections (2) · Oxygen (2) · Remifentanil (2) · Amoxicillin (1) · Cognitive Behavioral Therapy (1) · Electroconvulsive Therapy (1) · Etomidate (1) · High Fructose Corn Syrup (1) · Ketamine (1) · Monitoring, Physiologic (1) · Neostigmine (1) · Saline Solution (1) · Standard of Care (1) · Ventilation (1) · Ventilators, Mechanical (1)
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (3) · Capital Medical University (2) · Charite University, Berlin, Germany (2) · Radboud University Medical Center (2) · University of Utah (2) · Aga Khan University (1) · Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier des Pays de Morlaix (1) · Elif Tunç (1) · Eysz, Inc. (1) · Goethe University (1) · Insel Gruppe AG, University Hospital Bern (1) · Institute of Sport - National Research Institute, Poland (1) · KU Leuven (1) · Karolinska Institutet (1)
United States (6) · Germany (5) · France (4) · Canada (3) · Italy (3) · Sweden (3) · Switzerland (3) · United Kingdom (3) · Belgium (2) · China (2) · Netherlands (2) · Pakistan (2) · Poland (2) · Australia (1) · Czechia (1)
Thomas Langer, MD (3) · Antonio Pesenti, MD (2) · Giacomo Grasselli, MD (2) · Antonio M Pesenti, MD (1) · Asma Abdus Salam, Consultant anaesthesiology (1) · Balthasar Eberle, MD (1) · Christoph Krick, Dr.rer.med. (1) · Dwayne Westenskow (1) · Edoardo Calderini, MD (1) · Frantisek Duska, MD (1) · Giorgio Giudici, MD (1) · Gregor Hasler, Prof. Dr. med. (1)
PMID 35213875, PMID 10492412, PMID 10793602, PMID 12717123, PMID 1356374, PMID 17893459, PMID 20576632, PMID 21522210, PMID 22091288, PMID 22901344, PMID 23372884, PMID 26400417, PMID 27941119, PMID 28807986, PMID 29261883, PMID 29730991, PMID 30573962, PMID 30760295, PMID 31640632, PMID 32089047, PMID 34364365, PMID 34667360, PMID 3605668, PMID 36096944, PMID 36351728, PMID 37139057, PMID 40670486, PMID 40706939, PMID 41433250, PMID 6161627, PMID 9366929, PMID 9793671, PMID 9797517
R01MH066953 (1), R43NS129363 (1)