9 completed, 1 enrolling by invitation, 1 not yet recruiting, 1 recruiting. 10 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 7, Enrolling by invitation 1, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Hypocapnia: new trials by email Literature Review of Hypocapnia trials Research Report on Hypocapnia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Correcting Hypocapnia in Aneurysmal Subarachnoid Hemorrhage. Normobaric Facemask Oxygen, control group - Aneurysmal Subarachnoid Hemorrhage (aSAH) | Not yet recruiting | The Chinese University of Hong Kong, Shenzhen | 80 | 2026-01-01 | 2026-01-15 | |
| End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children High normal ETCO2: ETCO2 50 mmHg (+/- 3mmHg), Normal ETCO2: ETCO2 40 mmHg (+/- 3mmHg), Low Normal ETCO2: ETCO2 30 mmHg (+/- 3mmHg) - Anesthesia, Hypercapnia | Not applicable | Recruiting | University of British Columbia | 100 | 2024-06-25 | 2026-05-22 |
| Intraoperative Hypocapnia in PROVHILO and PROBESE intraoperative mechanical ventilation with hypocapnia (etCO2 < 35 mm Hg) - Mechanical Ventilation Complication, Surgery | Completed | NMC Specialty Hospital | 2793 | 2022-11-29 | 2023-05-06 | |
| Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia Chemoreflex Testing, Baroreflex testing, Orthostatic stress testing - Postural Orthostatic Tachycardia Syndrome, Hypocapnia | Not applicable | Unknown | New York Medical College | 30 | 2022-09-23 | 2023-06-28 |
| A Study to Evaluate the Effects of Sharpened Romberg Testing (SRT) in Healthy Subjects Increased breathing, sharpened Romberg test (SRT) - Hypocapnia, Balance; Distorted | Not applicable | Completed | Mayo Clinic | 20 | 2021-05-17 | 2023-01-17 |
| The Effect of Respiratory Challenge on the BOLD Signal Carbon Dioxide - Hypoxia, Brain, Hyperoxia | Not applicable | Enrolling by invitation | Washington University School of Medicine | 48 | 2020-01-29 | 2026-01-16 |
| Pulse Oximeter and Respiratory Rate Test Spry Loop Band - Hypoxia, Hypercapnia | Not applicable | Completed | Spry Health | 12 | 2018-12-12 | 2019-01-09 |
| Comparison of Transcutaneous Vs End-tidal CO2 Pressure Measurements in Hyperventilation Syndrome Diagnosis Simultaneous Transcutaneous and End-tidal CO2 measurements - Hyperventilation Syndrome, Hypocapnia | Not applicable | Completed | University Hospital, Rouen | 14 | 2017-12-21 | 2020-06-29 |
| Hypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2 5% carbon-dioxide inhalation - Hypoxic-Ischaemic Encephalopathy, Perinatal Asphyxia | Phase 1 | Completed | Semmelweis University | 10 | 2016-02-01 | 2021-04-26 |
| Study of the Impact of Changes in Carbonemia on Microcirculation in Patients Achieving a Test Hypercapnia confocal microscopy - Microcirculation, Blood Circulation | Not applicable | Completed | Centre Hospitalier Universitaire de Saint Etienne | 10 | 2013-05-01 | 2015-09-15 |
| The Role of Perioperative Ventilation (Gas Exchange) During Intrabdominal Surgery on Cognitive Function mechanical ventilation - Response to Hyperoxia, Hypocapnia | Not applicable | Completed | Northern State Medical University | 109 | 2012-10-01 | 2016-09-22 |
| Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol Rebreathing tube, No rebreathing tube (Nothing) - Anesthesia, Intravenous, Anesthesia Recovery Period | Not applicable | Completed | DongGuk University | 30 | 2012-01-01 | 2015-02-16 |
| Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR) End tidal CO2 monitor - Delivery Room Resuscitation | Not applicable | Completed | Neil Finer | 50 | 2009-10-01 | 2019-12-17 |
Hypercapnia (5) · Hyperoxia (2) · Hyperventilation (2) · Alkalosis, Respiratory (1) · Cognitive Dysfunction (1) · Hypoxia (1) · Hypoxia, Brain (1) · Hypoxia-Ischemia, Brain (1) · Intraoperative Complications (1) · Postoperative Complications (1) · Postural Orthostatic Tachycardia Syndrome (1) · Respiratory Aspiration (1) · Subarachnoid Hemorrhage (1)
Pathological Conditions, Signs and Symptoms (13) · Signs and Symptoms (13) · Signs and Symptoms, Respiratory (13) · Nervous System Diseases (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Pathologic Processes (3) · Respiration Disorders (3) · Respiratory Tract Diseases (3) · Cardiovascular Diseases (2) · Cerebrovascular Disorders (2) · Hypoxia (2) · Vascular Diseases (2) · Acid-Base Imbalance (1) · Alkalosis (1)
Carbon Dioxide (1) · Control Groups (1) · Microscopy, Confocal (1) · Respiration, Artificial (1)
Centre Hospitalier Universitaire de Saint Etienne (1) · DongGuk University (1) · Mayo Clinic (1) · NMC Specialty Hospital (1) · Neil Finer (1) · New York Medical College (1) · Northern State Medical University (1) · Semmelweis University (1) · Spry Health (1) · The Chinese University of Hong Kong, Shenzhen (1) · University Hospital, Rouen (1) · University of British Columbia (1) · Washington University School of Medicine (1)
United States (5) · France (2) · Brazil (1) · Canada (1) · China (1) · Germany (1) · Hungary (1) · Italy (1) · Russia (1) · South Korea (1) · Spain (1)
Christopher A Chin, MBBS, FRCA, FRCP, MA (1) · David MP van Meenen, PhD (1) · Frederique Paulus, PhD (1) · Jan Stepanek, MD, MPH (1) · Junyong In, M.D. (1) · Marcus J Schultz, PhD (1) · Marvin S Medow, Ph.D. (1) · Mikhail Y. Kirov, MD, PhD (1) · Renzhi Wang, MD (1) · Sabrine NT Hemmes, PhD (1) · Tina A Leone, MD (1) · Xinyu Yang (1)
PMID 12352026, PMID 17205016, PMID 19965840, PMID 25846710, PMID 34331211, PMID 34584136, PMID 38294526, PMID 39640813, PMID 40532319, PMID 40930872