10 completed, 5 unknown, 1 active not recruiting, 1 recruiting. 7 Not applicable, 2 Phase 2, 2 Phase 4, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Recruiting 1, Terminated 1 |
| Phase 1 | 1 | Active not recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow High Fructose Corn Syrup: new trials by email Literature Review of High Fructose Corn Syrup trials Research Report on High Fructose Corn Syrup
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age Prednisolone Sodium Phosphate, Sugar syrup - Bronchiolitis Acute Viral | Phase 4 | Recruiting | University of Oulu | 210 | 2022-10-11 | 2025-02-13 |
| Honey Against Sore Throat Honey - Sore Throat, Honey | Not applicable | Completed | Medipol University | 282 | 2022-01-06 | 2024-12-04 |
| Meta-analyses of Food Sources of Fructose-Containing Sugars and Obesity Fructose-containing Sugars - Body Weight, Obesity | Unknown | John Sievenpiper | 1 | 2018-09-04 | 2019-01-15 | |
| Liver Glycogen and Hypoglycemia in Humans Low Fructose, Saline, Somatostatin - Hypoglycemia; Iatrogenic | Phase 1 | Active not recruiting | Jason Winnick | 40 | 2018-08-02 | 2025-07-25 |
| Adverse Metabolic Effects of Dietary Sugar high fructose corn syrup, aspartame, Energy-balanced diet - Chronic Disease of Cardiovascular System, Type 2 Diabetes | Not applicable | Completed | University of California, Davis | 36 | 2016-02-01 | 2021-09-16 |
| Effect of Plant Omega-3 and Omega-6 Fatty Acids on Exercise Performance corn syrup, Polyunsaturated fatty acid - Effect of Essential Fatty Acids on Exercise Performance | Not applicable | Unknown | University of Western Ontario, Canada | 18 | 2016-02-01 | 2016-01-13 |
| Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases Fructose-containing Sugars - Diabetes Mellitus, Type 2, Metabolic Syndrome X | Unknown | University of Toronto | 1 | 2015-09-01 | 2016-08-24 | |
| A Study Evaluating the Effect of Vitamin D on Clinical Outcome in Autistic Children Vitamin D3, Placebo - Autism | Phase 2 | Completed | Ain Shams University | 42 | 2015-08-01 | 2016-07-12 |
| Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors Fructose-containing Sugars - Dyslipidemia, Diabetes | Unknown | University of Toronto | 1 | 2015-06-01 | 2020-06-25 | |
| Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk High Fructose Corn Syrup, Sucrose - Obesity, Dyslipidemia | Unknown | University of Toronto | 1 | 2014-06-01 | 2016-05-17 | |
| Appetite Suppression Trial With Polydextrose 12.5 g polydextrose, glucose syrup - Body Weight, Non-restrained Eaters | Not applicable | Completed | W.J. Pasman | 32 | 2014-05-01 | 2022-06-06 |
| Effect of B-GOS on GI Discomfort in Healthy Adults B-GOS, Maltodextrin - Healthy | Phase 3 | Completed | Clasado Limited | 400 | 2013-02-01 | 2013-11-27 |
| Lactose, Sucrose & Corn Syrup Tolerance corn syrup solids, sucrose - Focus of Study: Oral Tolerance Test With Glucose, Lactose, Sucrose | Not applicable | Completed | University of British Columbia | 16 | 2013-01-01 | 2026-04-13 |
| Community Based Management of Fast Breathing in Infants Aged < 60 Days in Low-income Settlements of Karachi Amoxicillin, Sugar Syrup - Fast Breathing in Young Infants | Phase 4 | Terminated | Aga Khan University | 963 | 2012-05-01 | 2014-06-03 |
| High Fructose Corn Syrup High fructose corn syrup diet, Standard diet (low in high fructose corn syrup) - Nonalcoholic Fatty Liver Disease, Obesity | Not applicable | Completed | Washington University School of Medicine | 47 | 2012-03-01 | 2017-03-27 |
| The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks Glucose, Fructose, High-Fructose Corn Syrup - Metabolic Syndrome, Insulin Resistance | Not applicable | Completed | University of California, Davis | 214 | 2008-10-01 | 2017-05-30 |
| Pharmacokinetics and Pharmacodynamics of Fructose Dr Pepper sweetened with sucrose or high fructose corn syrup - Healthy | Completed | University of Florida | 40 | 2008-03-01 | 2012-02-16 | |
| Effect of Replacing HFCS With Sucromalt in Subjects With Raised Waist Circumference High Fructose Corn Syrup, Sucromalt - Abdominal Obesity | Phase 2 | Completed | University of Toronto | 28 | 2006-09-01 | 2007-08-14 |
Body Weight (4) · Obesity (4) · Cardiovascular Diseases (3) · Dyslipidemias (3) · Gout (3) · Hypertension (3) · Insulin Resistance (3) · Non-alcoholic Fatty Liver Disease (3) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 2 (2) · Fasting (2) · Fatty Liver (2) · Metabolic Syndrome (2) · Obesity, Abdominal (2) · Prediabetic State (2)
University of Toronto (4) · University of California, Davis (2) · Aga Khan University (1) · Ain Shams University (1) · Clasado Limited (1) · Jason Winnick (1) · John Sievenpiper (1) · Medipol University (1) · University of British Columbia (1) · University of Florida (1) · University of Oulu (1) · University of Western Ontario, Canada (1) · W.J. Pasman (1) · Washington University School of Medicine (1)
Canada (7) · United States (5) · Egypt (1) · Finland (1) · Netherlands (1) · Pakistan (1) · Turkey (Türkiye) (1) · United Kingdom (1)
John L Sievenpiper, MD,PhD,FRCPC (2) · Jason Winnick, PhD (1) · Jean-Marc Schwarz, Ph.D. (1) · John Sievenpiper, MD,PhD,FRCPC (1) · Julie A Johnson, Pharm.D. (1) · Kimber L Stanhope, Ph.D, R.D. (1) · Kimber L Stanhope, Ph.D. (1) · Naguib Muhsen, MD (1) · Peter J Havel, D.V.M (1) · Peter J Havel, DVM, Ph.D (1) · Peter Lemon, PhD (1) · Samuel Klein, MD (1) · Sheila M Innis, PhD (1) · Shelby A Sullivan, MD (1)
PMID 22152650, PMID 25879513, PMID 25904601, PMID 27916475, PMID 27941119, PMID 30463844, PMID 31061018, PMID 31826724, PMID 32916151, PMID 34087940, PMID 34265055, PMID 34986271, PMID 36235639, PMID 36842451, PMID 37582096
R01HL091333 (1), R01HL107256 (1), R01HL121324 (1)