9 completed. 9 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 9 |
| Phase 1 | 4 | Completed 4 |
Follow Hyperthermia: new trials by email Literature Review of Hyperthermia trials Research Report on Hyperthermia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Cocaine and Temperature Regulation During Exercise Cocaine, Lidocaine - Hyperthermia, Cocaine Use | Phase 1 / Phase 2 | Completed | University of Texas Southwestern Medical Center | 27 | 2023-09-01 | 2025-07-14 |
| Heat Therapy, Functional Capacity, and Vascular Health in Older Adults Home-based leg heat therapy, Home-based sham therapy - Aging Well, Walking, Difficulty | Phase 1 / Phase 2 | Completed | University of North Texas Health Science Center | 21 | 2022-11-03 | 2026-06-05 |
| Assessment of Growth Factors Levels Associated with Wound Healing After Soft Tissue Crown Lengthening single intervention by Sirolase ® lower power diode laser 970 ± 15 nm (0.5 watts) continuous emission, power =3 watts, fiber 320 μm, single intervention by electrosurgical unit which was kept 38 watts rms ± 5%. The working frequency was adjusted to 1.5 MHz ± 5%. - Gingival Overgrowth | Phase 2 | Completed | Al-Azhar University | 80 | 2021-10-03 | 2025-02-04 |
| Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours Water-filtered infrared A radiation whole-body hyperthermia (HECKEL 3000MT-4T, Germany), tislelizumab (BeiGene, China) combined with PD-1 inhibitor - Gastrointestinal Tumor | Phase 1 / Phase 2 | Completed | Pengyuan Liu | 18 | 2020-06-01 | 2023-09-05 |
| Aggressive Antipyretics for Fever Reduction in CNS Malaria Acetaminophen, Ibuprofen, placebo for acetaminophen - Malaria, Seizures | Phase 2 | Completed | University of Rochester | 256 | 2019-01-07 | 2024-03-05 |
| Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury Bromocriptine 5 MG, Acetaminophen 650 MG - Subarachnoid Hemorrhage, Subdural Hematoma | Phase 1 / Phase 2 | Completed | University of California, San Francisco | 47 | 2018-11-30 | 2021-06-24 |
| Surgery and Heated Chemotherapy for Adrenocortical Carcinoma Cisplatin, Cytoreductive surgery, sodium thiosulfate - Adrenocortical Carcinoma, Peritoneal Carcinomatosis | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2013-04-12 | 2019-07-30 |
| Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer Deep regional hyperthermia, Radiotherapy, Chemotherapy (5-Fluorouracil) - Rectal Cancer, Locally Advanced Rectal Cancer | Phase 2 | Completed | University Hospital Tuebingen | 78 | 2012-08-01 | 2018-02-13 |
| A Phase II Study of Isolated Hepatic Perfusion (IHP) in Patients With Ocular Melanoma Laparotomy - Melanoma | Phase 2 | Completed | National Cancer Institute (NCI) | 40 | 2003-06-01 | 2012-08-20 |
Fever (2) · Adrenocortical Carcinoma (1) · Brain Injuries, Traumatic (1) · Camurati-Engelmann Syndrome (1) · Cerebral Hemorrhage (1) · Coma (1) · Digestive System Neoplasms (1) · Eye Neoplasms (1) · Gingival Overgrowth (1) · Hematoma, Subdural (1) · Hyperemia (1) · Ischemic Stroke (1) · Malaria (1) · Melanoma (1)
Body Temperature Changes (9) · Heat Stress Disorders (9) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Wounds and Injuries (9) · Neoplasms (4) · Neoplasms by Site (4) · Digestive System Diseases (3) · Pathologic Processes (3) · Cardiovascular Diseases (2) · Digestive System Neoplasms (2) · Neoplasms by Histologic Type (2) · Nervous System Diseases (2) · Vascular Diseases (2) · Abdominal Neoplasms (1)
Acetaminophen (2) · Bromocriptine (1) · Cisplatin (1) · Cocaine (1) · Cytoreduction Surgical Procedures (1) · Drug Therapy (1) · Fluorouracil (1) · Ibuprofen (1) · Immune Checkpoint Inhibitors (1) · Laparotomy (1) · Lidocaine (1) · Radiotherapy (1) · sodium thiosulfate (1) · spartalizumab (1) · tislelizumab (1)
National Cancer Institute (NCI) (2) · Al-Azhar University (1) · Pengyuan Liu (1) · University Hospital Tuebingen (1) · University of California, San Francisco (1) · University of North Texas Health Science Center (1) · University of Rochester (1) · University of Texas Southwestern Medical Center (1)
United States (5) · China (1) · Egypt (1) · Germany (1) · Malawi (1) · Zambia (1)
Gretchen L Birbeck, MD (1) · Jeremy L Davis, M.D. (1) · Judy H Ch'ang, MD (1) · Jun Chen (1)
PMID 30463745, PMID 33741467, PMID 36316704, PMID 38640099, PMID 38857015
R01NS102176 (1)