27 completed, 9 unknown, 3 active not recruiting, 3 recruiting. 21 Not applicable, 6 Phase 3, 4 Phase 2, 2 Phase 4, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Intravenous Lidocaine Versus Placebo in Patients Receiving Morphine-rachi Analgesia rachi morphine anesthesia, laparotomy, Lidocaine IV - Digestive System Disease, Surgery | Phase 3 | Not yet recruiting | GCS Ramsay Santé pour l'Enseignement et la Recherche | 76 | 2026-09-01 | 2026-08-25 |
| The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in Rats Dexmedetomidine, Remifentanil, Laparotomy - Acute Kidney Injury, Crush Injury | Not applicable | Completed | Ankara City Hospital Bilkent | 28 | 2024-07-10 | 2025-07-30 |
| Study of the Influence of Intraperitoneal Insufflation of CO2 by Laparoscopy on the Short-term Evolution of Premature Infants With Ulcerative Necrotizing Enterocolitis laparotomy, Laparoscopy - Preterm Birth, Enterocolitis, Necrotizing | Not applicable | Unknown | Assistance Publique - Hôpitaux de Paris | 54 | 2024-02-22 | 2024-02-28 |
| The Use of MicroRNAs Dysregulation as Potential Biomarkers for Effective Diagnosis of Endometriosis 100 women undergoing surgery (laparoscopy / laparotomy) with presumed diagnosis of endometriosis, women with intraoperative and / or histopathology findings suggestive of endometriosis - Endometriosis | Not applicable | Active not recruiting | Asian Institute of Gastroenterology, India | 200 | 2023-11-15 | 2023-12-13 |
| Ovary Syndrome for Efficient Diagnosis and Targeted Therapy laparoscopy / laparotomy, NO INTERVENTION - Polycystic Ovary Syndrome | Not applicable | Not yet recruiting | Asian Institute of Gastroenterology, India | 200 | 2023-11-05 | 2023-10-26 |
| Diagnostic Accuracy of Ultrasound and Tumors Markers in Diagnosis of Complex Ovarian Cysts Laparotomy or laparoscopic ovarian cystectomy - Complex Ovarian Cyst | Not applicable | Completed | Al-Azhar University | 48 | 2023-02-10 | 2025-06-05 |
| Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy Epidural analgesia, Bilateral rectus sheath block, Laparotomy - Laparotomy | Not applicable | Recruiting | Centre Hospitalier Régional Metz-Thionville | 110 | 2021-10-11 | 2025-12-16 |
| Value of the Laparoscopic Approach in the Surgical Management of Resectable Hepatocellular Carcinoma Laparoscopy, Laparotomy - Hepatocellular Carcinoma | Not applicable | Active not recruiting | Assistance Publique - Hôpitaux de Paris | 252 | 2021-05-21 | 2025-05-28 |
| Endometrial Carcinoma: Comparison of Surgical Approaches (Laparoscopy vs Laparotomy) Laparotomy, Laparoscopy - Endometrial Carcinoma | Active not recruiting | Azienda USL Reggio Emilia - IRCCS | 700 | 2021-05-10 | 2026-05-07 | |
| The Best Care for Abdominal Emergencies Study Laparotomy or laparoscopy - Acute Abdomen, Bowel Obstruction | Completed | Portsmouth Hospitals NHS Trust | 2500 | 2021-01-08 | 2025-12-26 | |
| Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial Chemotherapy, Laparotomy, Minimally Invasive Surgery - Advanced Ovarian Carcinoma, Fallopian Tube Clear Cell Adenocarcinoma | Phase 3 | Recruiting | M.D. Anderson Cancer Center | 580 | 2020-08-05 | 2026-09-14 |
| Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies Hydromorphone, Laparotomy, Liposomal Bupivacaine - Malignant Female Reproductive System Neoplasm | Phase 4 | Completed | Mayo Clinic | 105 | 2020-07-09 | 2024-10-16 |
| Impact of Nutritional Deficit in Emergency Surgery Emergency laparotomy - Emergencies, Surgery | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 59 | 2020-01-01 | 2021-10-08 | |
| A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes Exploratory laparotomy - Pancreatic Trauma, Pancreatic Duct Injury | Completed | Kern Medical Center | 31 | 2019-11-01 | 2024-01-29 | |
| Survival Outcome After Minilaparotomy for the Treatment of Colorectal Cancer Colorectal cancer resection via minilaparotomy, Laparoscopic colorectal cancer resection - Colorectal Cancer | Not applicable | Unknown | Changhai Hospital | 992 | 2019-04-01 | 2019-02-18 |
| Outcomes After Laparotomy for Penetrating Abdominal Trauma Laparotomy - Penetrating Abdominal Trauma | Completed | Karolinska Institutet | 196 | 2019-04-01 | 2020-09-03 | |
| Fibroids and Infertility - a Study of the Significance of Removal of Fibroids With Regard to Endometrial Receptivity Transcervical resection of fibroids, Myomectomy per laparoscopy or laparotomy - Leiomyoma, Uterine | Unknown | Oslo University Hospital | 80 | 2019-03-01 | 2020-06-11 | |
| Comparison of Open Laparoscopic and Robotic Surgery in Gastric Cancer Resection. laparotomy, Laparoscopic, Robotic - Stomach Neoplasms | Not applicable | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 500 | 2018-02-28 | 2018-03-02 |
| HIPEC and Systemic Chemotherapy in Unresectable Peritoneal Metastases From Colorectal Cancer exploratory laparoscopy or laparotomy, HIPEC, Systemic chemotherapy - Peritoneal Metastases From Colorectal Cancer | Not applicable | Terminated | Wuhan University | 15 | 2018-02-01 | 2020-03-24 |
| OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer OTL38, near infrared camera imaging system, laparotomy - Ovarian Cancer | Phase 3 | Completed | On Target Laboratories, LLC | 140 | 2018-01-26 | 2022-02-04 |
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Ovarian Neoplasms (8) · Endometriosis (4) · Colonic Neoplasms (3) · Enterocolitis, Necrotizing (3) · Premature Birth (3) · Colorectal Neoplasms (2) · Endometrial Neoplasms (2) · Fallopian Tube Neoplasms (2) · Infertility (2) · Intestinal Obstruction (2) · Intestinal Perforation (2) · Pancreatitis, Acute Necrotizing (2) · Abdomen, Acute (1) · Abdominal Abscess (1) · Abdominal Injuries (1)
Assistance Publique - Hôpitaux de Paris (3) · Asian Institute of Gastroenterology, India (2) · National Cancer Institute (NCI) (2) · On Target Laboratories, LLC (2) · Wuhan University (2) · Al-Azhar University (1) · Alliance for Clinical Trials in Oncology (1) · Angle plc (1) · Ankara City Hospital Bilkent (1) · Azienda USL Reggio Emilia - IRCCS (1) · Centre Francois Baclesse (1) · Centre Hospitalier Régional Metz-Thionville (1) · Changhai Hospital (1) · EZH EAH (1) · First Affiliated Hospital Xi'an Jiaotong University (1)
United States (12) · France (8) · China (3) · Turkey (Türkiye) (3) · India (2) · Italy (2) · Netherlands (2) · United Kingdom (2) · Australia (1) · Austria (1) · Canada (1) · Egypt (1) · Finland (1) · Germany (1) · Hong Kong (1)
Shraddha Ramchandani (2) · Abbot R. Laptook, MD (1) · Abhik Das, PhD (1) · Amber Jones, DO, MPH (1) · Amy D. Tiersten, MD (1) · Antti Perheentupa, MD, PhD (1) · Barbara Schmidt, MD, MSc (1) · Berna Dilbaz, Prof. (1) · Brad Yoder, MD (1) · Brenda Poindexter, MD, MS (1) · C. Michael Cotten, MD (1) · Carl D'Angio, MD (1) · Cuneyt Kayaalp (1) · David Carlton, MD (1)
PMID 11913730, PMID 12782596, PMID 16505413, PMID 16723614, PMID 19138791, PMID 19142813, PMID 19337252, PMID 19663710, PMID 20026830, PMID 20783577, PMID 22426487, PMID 22969138, PMID 23347808, PMID 23574119, PMID 23657066, PMID 24224624, PMID 24907872, PMID 25010612, PMID 25024303, PMID 25099244, PMID 25137424, PMID 25294552, PMID 25613736, PMID 26166344, PMID 27598600, PMID 28079776, PMID 28331287, PMID 29748435, PMID 30125215, PMID 31801485, PMID 32317860, PMID 32717180, PMID 34432874, PMID 34761118, PMID 35289396, PMID 35882475, PMID 36070540, PMID 37026805, PMID 37169336, PMID 37221022, PMID 37741988, PMID 39570589
2009 (1), 2025 (1), M01RR008084 (1), U10CA031946 (1), U10CA032102 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD027851 (1), U10HD027853 (1), U10HD027856 (1), U10HD027871 (1), U10HD027880 (1), U10HD027904 (1), U10HD034216 (1)