58 completed, 15 recruiting, 13 unknown, 5 terminated. 30 Not applicable, 11 Phase 2, 10 Phase 3, 10 Phase 4, 5 Phase 1.
Follow Hyperparathyroidism, Primary: new trials by email Literature Review of Hyperparathyroidism, Primary trials Research Report on Hyperparathyroidism, Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Parathyroid Adenoma Detection With Rubidium-82 Imaging PET/CT imaging with rubidium-82 - Parathyroid Adenomas, Hyperparathyroidism, Primary | Enrolling by invitation | Matthieu Pelletier-Galarneau, MD MSc | 20 | 2026-11-01 | 2026-10-27 | |
| Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism Scheduling Navigation, Without Scheduling Navigation - Hyperparathyroidism, Primary | Not applicable | Recruiting | University of Pennsylvania | 76 | 2026-10-01 | 2026-08-27 |
| NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism NIRAF-camera - Primary Hyperparathyroidism | Not applicable | Recruiting | The Cleveland Clinic | 80 | 2026-08-31 | 2026-09-11 |
| Shortwave Infrared Surgical Imaging Device Study Observational study of SWIR imaging device in surgery - Cholecystitis, Cholecystitis, Chronic | Enrolling by invitation | Cision Vision, Inc. | 50 | 2026-05-29 | 2026-08-04 | |
| Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors 18F-FCH, NeuroEXPLORER - Primary Hyperparathyroidism, Parathyroid Cancer | Phase 2 / Phase 3 | Recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 193 | 2026-04-16 | 2026-06-02 |
| Aldosterone Variations in Patients With Primary Hyperparathyroidism After Surgery Primary Hyperparathyroidism, Primary Hyperparathyroidism Due to Adenoma | Not yet recruiting | Central Hospital, Nancy, France | 400 | 2026-02-01 | 2026-02-05 | |
| Evaluation of the Role of Luteinizing Hormone (LH) and Human Chorionic Gonadotropin (hCG) in Adult Patients Undergoing Assessment for Endocrine Disorders Osteoporosis, Hypercalcemia | Recruiting | Martin Blomberg Jensen | 20000 | 2026-01-01 | 2026-09-17 | |
| Is Intraoperative PTH Monitoring Obsolete in Times of Choline PET/CT? a Prospective Multicenter Cohort Study to Determine Whether the Regular Preoperative Use of Choline-PET/CT Scan Obviate the Need for Intraoperative PTH-measurement in Patients with Primary Hyperparathyreoidism Primary Hyperparathyroidism | Not yet recruiting | University of Zurich | 1000 | 2025-09-01 | 2025-02-03 | |
| WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-Making Near-Infrared Parathyroid Tissue Sensor Imaging (PTS), Rim-Preservation Technique, En-bloc Resection Technique - Hyperparathyroidism, Primary, Parathyroid Neoplasms | Not applicable | Not yet recruiting | Fujian Medical University | 120 | 2025-07-01 | 2025-06-29 |
| Bisphosphonate Prior to Parathyroidectomy in Primary Hyperparathyroidism Zoledronic acid 4 mg, Natriumklorid 9 mg/ml, Fresenius Kabi - Primary Hyperparathyroidism | Phase 4 | Recruiting | University of Aarhus | 140 | 2025-03-01 | 2026-10-01 |
| Diagnostic Performance of [11C]Choline PET/CT In the Preoperative Assessment of Primary Hyperparathyroidism PET/CT - Primary Hyperparathyroidism | Not yet recruiting | IRCCS San Raffaele | 200 | 2025-01-01 | 2024-10-22 | |
| Near Infrared Autofluorescence Imaging in Minimally-Invasive Video-Assisted Parathyroidectomy (NIRAF MIVAP Study) parathyroidectomy - Primary Hyperparathyroidism Due to Adenoma | Completed | Aristotle University Of Thessaloniki | 24 | 2024-09-20 | 2025-01-17 | |
| Parathyroid Assessment of Symptoms French Version SF-36 questionnaire French version and PAS.fr questionnaire - Quality of Life in Primary Hyperparathyroidism | Recruiting | Nantes University Hospital | 548 | 2024-07-01 | 2026-05-04 | |
| Evaluation of the Role of Intraoperative Neuromonitoring(IONM) in Patients Undergoing Parathyroid Surgery for Solitary Parathyroid Adenoma INTRAOPERATIVE NEUROMONITORING - Evaluation of the Role of IONM in Minimally Invasive Parathyroidectomy Performed for Solitary Parathyroid Adenoma | Not applicable | Completed | Izmir Katip Celebi University | 100 | 2024-02-21 | 2026-09-23 |
| Autofluorescence in Surgery for Primary Hyperparathyroidism Surgery with autofluorescence - Hyperparathyroidism, Primary | Not applicable | Recruiting | Aarhus University Hospital | 100 | 2024-01-01 | 2025-01-29 |
| Upfront Ultrasound for Preoperative Localization in Primary Hyperparathyroidism Primary Hyperparathyroidism | Completed | Odense University Hospital | 99 | 2023-09-01 | 2026-01-14 | |
| Parathyroid Tumor Clonal Status Parathyroid Tumor, Primary Hyperparathyroidism | Recruiting | Washington University School of Medicine | 839 | 2023-07-28 | 2026-05-12 | |
| Glycemic Control, Type II Diabetes, Parathyroidectomy Urine and Blood Test - Primary Hyperparathyroidism, Type 2 Diabetes | Active not recruiting | The Cleveland Clinic | 80 | 2023-02-27 | 2026-05-26 | |
| 18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Imaging for Localizing Diseased Parathyroid Glands in Primary Hyperparathyroidism Parathyroidectomy - Primary Hyperparathyroidism | Not applicable | Recruiting | Region Skane | 88 | 2023-01-01 | 2025-08-24 |
| European Multicentric Study on Parathyroid Carcinoma Surgical treatment of parathyroid carcinoma - Parathyroid Carcinoma | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 17 | 2022-12-15 | 2023-03-29 |
Showing 20 of 101. Sign in to see all of them.
Parathyroid Neoplasms (22) · Hypercalcemia (13) · Hyperparathyroidism (13) · Osteoporosis (11) · Bone Diseases, Metabolic (8) · Vitamin D Deficiency (6) · Hyperparathyroidism, Secondary (4) · Multiple Endocrine Neoplasia Type 1 (3) · Osteoporosis, Postmenopausal (3) · Parathyroid Diseases (3) · Thyroid Diseases (3) · Hypocalcemia (2) · Acromegaly (1) · Adenoma (1)
Endocrine System Diseases (100) · Parathyroid Diseases (98) · Hyperparathyroidism (88) · Nutritional and Metabolic Diseases (30) · Metabolic Diseases (29) · Neoplasms (24) · Neoplasms by Site (23) · Endocrine Gland Neoplasms (22) · Head and Neck Neoplasms (22) · Musculoskeletal Diseases (17) · Bone Diseases (16) · Calcium Metabolism Disorders (16) · Water-Electrolyte Imbalance (15) · Bone Diseases, Metabolic (7) · Avitaminosis (6)
Cinacalcet (13) · Parathyroidectomy (6) · Cholecalciferol (5) · Vitamin D (4) · Alendronate (3) · Denosumab (3) · fluorocholine (3) · Magnetic Resonance Spectroscopy (2) · Surgical Procedures, Operative (2) · Zoledronic Acid (2) · Amiloride (1) · Calcitonin (1) · Calcium (1) · Calcium Carbonate (1) · Congresses as Topic (1)
Amgen (7) · Columbia University (6) · M.D. Anderson Cancer Center (4) · Nantes University Hospital (3) · The Cleveland Clinic (3) · University of Aarhus (3) · University of Pennsylvania (3) · Aristotle University Of Thessaloniki (2) · Assistance Publique - Hôpitaux de Paris (2) · Central Hospital, Nancy, France (2) · HaEmek Medical Center, Israel (2) · Karolinska University Hospital (2) · Kyowa Kirin Co., Ltd. (2) · Medical University of Vienna (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2)
United States (31) · France (12) · Denmark (9) · Canada (5) · Italy (5) · Sweden (5) · Israel (3) · Switzerland (3) · Austria (2) · China (2) · India (2) · Japan (2) · Mexico (2) · Poland (2) · Russia (2)
Nancy D. Perrier, MD (3) · Bruno Niederle, Prof., MD (2) · Judy Jin, MD (2) · Shonni J Silverberg, MD (2) · Shonni J. Silverberg, MD (2) · Smita Jha, M.D. (2) · Thomas Hope, MD (2) · Adrienne Brouwers, MD PhD (1) · Anand Vaidya, MD MMSc (1) · Anders Bergenfelz, MD, Ass Prof (1) · Anders OJ Bergenfelz, MD, PhD (1) · Anne F Cailleux, MD (1) · Arturo Chiti, MD (1)
PMID 40668552, PMID 20943783, PMID 10898180, PMID 15522938, PMID 15663056, PMID 16540904, PMID 16785355, PMID 17071309, PMID 17216827, PMID 17284629, PMID 17666472, PMID 17879694, PMID 19160424, PMID 19351725, PMID 19470620, PMID 19837909, PMID 19950385, PMID 20035529, PMID 20395857, PMID 21044114, PMID 21207016, PMID 21679561, PMID 24026893, PMID 24115138, PMID 25162665, PMID 25414430, PMID 25636048, PMID 25645432, PMID 25820553, PMID 25975331, PMID 26031271, PMID 26435425, PMID 27626477, PMID 28522130, PMID 28937873, PMID 29294178, PMID 30727928, PMID 30860588, PMID 31595982, PMID 32333877, PMID 33585500, PMID 35018442, PMID 35138562, PMID 35436153, PMID 36917123, PMID 37052913, PMID 37284613, PMID 37288292, PMID 37339334, PMID 37597095
R01CA212147 (3), R01DK032333 (2), R01DK084986 (2), 2008 (1), 2016 (1), 2018 (1), 2023 (1), P30CA016672 (1), R01DK066329 (1)