481 completed, 176 unknown, 147 recruiting, 134 terminated. 354 Phase 2, 273 Phase 1, 239 Not applicable, 60 Phase 3, 17 Phase 4.
Follow Adenoma: new trials by email Literature Review of Adenoma trials Research Report on Adenoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas - Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor | Not applicable | Enrolling by invitation | Ohio State University Comprehensive Cancer Center | 12 | 2027-10-01 | 2026-10-13 |
| A Safety Study of ST316 in Participants With Familial Adenomatous Polyposis (FAP). ST316 IV - Familial Adenomatous Polyposis (FAP) | Phase 1 | Not yet recruiting | Sapience Therapeutics | 40 | 2027-01-04 | 2026-08-12 |
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas Biospecimen Collection, Computed Tomography, Incomplete Freund''s Adjuvant - Digestive System Neuroendocrine Neoplasm, Lung Neuroendocrine Neoplasm | Phase 2 | Not yet recruiting | Roswell Park Cancer Institute | 60 | 2026-12-15 | 2026-10-20 |
| A Phase 3 Trial in Advanced Epithelioid Mesothelioma VT3989, gemcitabine, Vinorelbine - Pleural Mesothelioma, Mesothelioma | Phase 3 | Not yet recruiting | Vivace Therapeutics, Inc | 350 | 2026-12-01 | 2026-09-17 |
| S-Adenosylmethionine (SAMe) for Chemoprevention of Colorectal Adenomas S-Adenosylmethionine (SAMe) - Colorectal Cancer (Diagnosis), Adenoma | Phase 1 | Not yet recruiting | Jun Gong, MD | 18 | 2026-11-01 | 2026-08-04 |
| Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma Ivonescimab Combined With Chemotherapy - Malignant Pleural Mesothelioma, Advanced | Phase 1 / Phase 2 | Recruiting | Ruijin Hospital | 78 | 2026-11-01 | 2026-10-26 |
| Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung Cancer Implantable Micro- drug delivery Microdevice (IMD) - Lung Cancer, Mesothelioma | Early Phase 1 | Not yet recruiting | Oliver Jonas | 20 | 2026-10-30 | 2026-10-23 |
| Protein Signature Based Screening of Colorectal Adenomas and Cancer Colorectal Cancer, Colorectal Adenoma | Enrolling by invitation | Region Skane | 150 | 2026-10-09 | 2026-10-19 | |
| Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging - Colorectal Neoplasms, Colonic Polyps | Not applicable | Not yet recruiting | Alexandre Vontobel Padoin | 990 | 2026-10-01 | 2026-09-01 |
| Comparison of [68Ga]Ga-HBED-CC-PEG6-Exendin-4 and [68Ga]Ga-HBED-CC-Exendin-4 PET/CT for Insulinoma Localization [68Ga]Ga-HBED-CC-PEG6-exendin-4 PET/CT, [68Ga]Ga-HBED-CC-exendin-4 PET/CT - Insulinoma | Not applicable | Recruiting | Peking Union Medical College Hospital | 20 | 2026-10-01 | 2026-09-09 |
| Optimizing Risk Assessment Through cfDNA in Pancreatic Neuroendocrine Tumors for Clinical Evaluation cfDNA molecular profiling - Pancreatic Neuroendocrine Tumor | Active not recruiting | Massimo Falconi | 30 | 2026-09-12 | 2026-09-16 | |
| Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis Rapamycin - Familial Adenomatous Polyposis | Phase 2 | Not yet recruiting | University Hospital, Toulouse | 25 | 2026-09-01 | 2026-05-08 |
| PRESTO: A Phase III Randomised Controlled Trial of Dose-escalated Proton Beam Therapy Versus Standard of Care Radiotherapy for Functioning Pituitary Tumours Standard dose Intensity-Modulated Radiation Therapy (IMRT), Standard dose Proton Beam Therapy (PBT), Escalated dose Proton Beam Therapy (PBT) - Acromegaly Due to Pituitary Adenoma, Cushing's Disease | Phase 3 | Not yet recruiting | University College, London | 82 | 2026-09-01 | 2026-10-01 |
| Effectiveness of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Routine Clinical Practice : a Prospective Multicenter Randomized Trial AI-Assisted Colonoscopy - Colorectal Neoplasms, Colonic Polyp | Not applicable | Not yet recruiting | Zhejiang University | 3300 | 2026-09-01 | 2026-09-16 |
| TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors TLN-499, Venetoclax - Small Cell Lung Cancer ( SCLC ), Neuroendocrine Cancer | Phase 1 | Recruiting | Treeline Biosciences, Inc. | 120 | 2026-08-05 | 2026-10-01 |
| FAPI PET Imaging - An Exploratory Study [18F]FAPI-74 PET/CT - Thyroid Pathology, Head and Neck Cancer (H&N) | Phase 1 / Phase 2 | Not yet recruiting | Martin Huellner | 770 | 2026-08-01 | 2026-07-15 |
| Recurrence After Gastric and Intestinal Polyp Resection Gastric Polyps, Intestinal Polyps | Not yet recruiting | LanZhou University | 2000 | 2026-07-26 | 2026-06-09 | |
| Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL) Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy - Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal | Not applicable | Recruiting | London North West Healthcare NHS Trust | 50 | 2026-07-09 | 2026-07-24 |
| A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors SHY-ONC6 - Advanced or Metastatic Solid Tumors, Triple Negative Breast Cancer (TNBC) | Phase 1 | Recruiting | SHY Therapeutics | 30 | 2026-06-24 | 2026-10-22 |
| Evaluation of Skin Tests in Biotherapy Allergies Drug skin tests (investigating hypersensitivity to a biotherapy) - Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Melanoma Neoplasms | Not applicable | Recruiting | University Hospital, Angers | 70 | 2026-06-17 | 2026-06-18 |
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Mesothelioma, Malignant (329) · Mesothelioma (295) · Colorectal Neoplasms (160) · Carcinoma, Non-Small-Cell Lung (131) · Adenoma, Islet Cell (113) · Adenomatous Polyposis Coli (92) · Pancreatic Neoplasms (91) · Neoplasms (83) · Lung Neoplasms (81) · Ovarian Neoplasms (72) · Stomach Neoplasms (70) · Colonic Neoplasms (67) · Carcinoma, Renal Cell (66) · Melanoma (66)
Neoplasms by Histologic Type (1087) · Neoplasms, Glandular and Epithelial (1087) · Neoplasms (1009) · Neoplasms by Site (894) · Neoplasms, Mesothelial (564) · Digestive System Diseases (514) · Digestive System Neoplasms (506) · Thoracic Neoplasms (461) · Respiratory Tract Diseases (458) · Respiratory Tract Neoplasms (457) · Lung Diseases (451) · Lung Neoplasms (372) · Gastrointestinal Diseases (336) · Pleural Neoplasms (335)
Cisplatin (79) · Pemetrexed (73) · pembrolizumab (39) · Nivolumab (28) · Carboplatin (25) · Colonoscopy (24) · Gemcitabine (22) · Cyclophosphamide (19) · Everolimus (16) · Ipilimumab (16) · Bevacizumab (12) · Drug Therapy (12) · Temozolomide (11) · Celecoxib (10) · Doxorubicin (10)
National Cancer Institute (NCI) (80) · Memorial Sloan Kettering Cancer Center (22) · M.D. Anderson Cancer Center (15) · Dana-Farber Cancer Institute (13) · Mayo Clinic (11) · Changhai Hospital (10) · University of Chicago (10) · Hospices Civils de Lyon (9) · Novartis Pharmaceuticals (9) · Peking Union Medical College Hospital (9) · Alliance for Clinical Trials in Oncology (8) · Fudan University (8) · Air Force Military Medical University, China (7) · Eli Lilly and Company (7) · European Organisation for Research and Treatment of Cancer - EORTC (7)
United States (518) · China (104) · United Kingdom (99) · Italy (98) · France (91) · Canada (65) · Netherlands (65) · Germany (60) · Spain (55) · Australia (49) · Belgium (42) · South Korea (31) · Denmark (27) · Switzerland (26) · Japan (24)
David S Schrump, M.D. (12) · Raffit Hassan, M.D. (12) · Ralf Kiesslich, Prof. (6) · Armando Santoro, MD (5) · Yanglin Pan, MD (5) · Dean Fennell (4) · Hedy Kindler (4) · Raphael Bueno, MD (4) · Xianjun Yu, MD, PhD (4) · Amit Rastogi, MD (3)
PMID 33358660, PMID 37119510, PMID 28192823, PMID 28970290, PMID 29802852, PMID 31576173, PMID 34289971, PMID 34499875, PMID 35048355, PMID 36053283, PMID 36104949, PMID 37279993, PMID 42580817, PMID 10500494, PMID 11165136, PMID 11487589, PMID 11880025, PMID 11950803, PMID 12059059, PMID 12190102, PMID 12244504, PMID 12374237, PMID 12390688, PMID 12565988, PMID 12584223, PMID 12612542, PMID 12621133, PMID 12803654, PMID 12825872, PMID 12872086, PMID 12934784, PMID 14627787, PMID 14673042, PMID 14750648, PMID 15081648, PMID 15084390, PMID 15306594, PMID 15764728, PMID 15951645, PMID 16030428, PMID 16148287, PMID 16192580, PMID 16267335, PMID 16281143, PMID 16329016, PMID 16373279, PMID 16374224, PMID 16412216, PMID 16446322, PMID 16554548
2016 (8), 2019 (8), 2023 (8), U10CA031946 (8), P30CA016672 (7), 2015 (5), U10CA032102 (5), 2017 (4), P30CA015083 (4), U10CA021115 (4), 2025 (3), P30CA014599 (3), P30CA068485 (3), U10CA180821 (3), U10CA180888 (3)