245 completed, 37 unknown, 16 recruiting, 9 active not recruiting. 74 Phase 3, 71 Not applicable, 71 Phase 4, 34 Phase 2, 24 Phase 1.
Follow Osteoporosis, Postmenopausal: new trials by email Literature Review of Osteoporosis, Postmenopausal trials Research Report on Osteoporosis, Postmenopausal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis Exercise training - Osteopenia, Osteoporosis | Not applicable | Withdrawn | University of Alabama at Birmingham | 2026-12-01 | 2026-07-01 | |
| Study of TST002 Injection in Postmenopausal Women With Osteoporosis or Low Bone Mass Denosumab, Placebo - Postmenopausal Osteoporosis, Low Bone Mass | Phase 2 | Not yet recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 110 | 2026-10-31 | 2026-09-11 |
| Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization - Postmenopausal Osteoporosis | Not applicable | Not yet recruiting | Riphah International University | 40 | 2026-09-01 | 2026-10-15 |
| The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation Ibandronate IV, Zoledronic acid IV - Postmenopausal Osteoporosis, Postmenopausal Osteopenia | Phase 4 | Recruiting | National Taiwan University Hospital | 52 | 2026-08-20 | 2026-08-25 |
| High-Intensity Laser Therapy and Physiotherapy for Bone Health in Postmenopausal Women: A Randomized Trial High-Intensity Laser Therapy, Sham Laser, Standardised Physiotherapy Programme - Osteoporosis, Postmenopausal, Osteopenia | Not applicable | Not yet recruiting | Iuliu Hatieganu University of Medicine and Pharmacy | 40 | 2026-07-27 | 2026-07-29 |
| Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females Blackcurrant (BC) extract, Placebo - Postmenopausal Osteoporosis, Gut Microbiome | Phase 1 | Recruiting | University of Connecticut | 159 | 2026-07-01 | 2026-07-23 |
| Romosozumab Effects on Bone Density, Muscle Mass, and Spine Surgery Outcomes Romosozumab, Alendronate (Fosamax), Placebo Romosozumab - Osteoporosis, Post-menopausal | Phase 2 | Withdrawn | University of Pittsburgh | 2026-06-20 | 2026-06-04 | |
| A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women Menopause, Menopausal Hormone Therapy | Not yet recruiting | IRCCS San Raffaele | 5000 | 2026-06-01 | 2026-05-26 | |
| Can Serum Lumican Level Identify a Hidden Fragility Phenotype Beyond Bone Mineral Density in Postmenopausal Women? Osteoporosis, Postmenopausal Osteoporosis | Recruiting | Kanuni Sultan Suleyman Training and Research Hospital | 98 | 2026-05-15 | 2026-06-30 | |
| AGE Burden and Response to Antiresorptive Therapy in Osteoporosis Osteoporosis, Postmenopausal Osteoporosis | Not yet recruiting | Bursa City Hospital | 240 | 2026-01-15 | 2026-01-09 | |
| Telerehabilitation Versus Traditional Balance Training in Women With Osteoporosis. Telerehabilitation group, Traditional balance training group - Osteoporosis Postmenopausal | Not applicable | Withdrawn | Riphah International University | 2026-01-01 | 2026-08-27 | |
| Prunes Preventing Bone Loss in Perimenopause Prunes, Calcium supplement, Vitamin D Supplement - Perimenopausal Bone Loss | Not applicable | Recruiting | Penn State University | 124 | 2025-12-11 | 2026-02-04 |
| The Investigation of the Effectiveness of Virtual Reality Applications in Postmenopausal Osteoporosis Patients Conventional treatment, Virtual reality treatment - Osteoperosis | Not applicable | Recruiting | Kirsehir Ahi Evran Universitesi | 50 | 2025-11-20 | 2026-02-27 |
| Effect of Mechanical Loading and Bone Loss on Motor Neuron Activity-H-Reflex Relationship H-reflex, Bone myoregulation reflex - Osteoporosis Postmenopausal | Not applicable | Recruiting | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 24 | 2025-11-18 | 2025-11-28 |
| StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis a second infusion of ZOL when crosslaps levels reach 300 pg/mL, a rescue second infusion at month-12 (standard traitment) - Postmenopausal Osteoporosis | Phase 4 | Recruiting | University Hospital, Toulouse | 200 | 2025-10-02 | 2025-12-31 |
| COMPASS - COpenhagen MenoPAuSe Study Triptorelin 11.25 mg, Sodium Chloride 0.9%, Estradiol (E2) - Menopausal Osteoporosis, Bone Markers | Phase 2 | Recruiting | Martin Blomberg Jensen | 192 | 2025-10-02 | 2026-03-02 |
| Bone Turnover Markers and Treatment Efficacy in Postmenopausal Osteoporosis Alendronate, Ibandronate; Risedronate, Teriparatide - Osteoporosis, Osteoporosis, Postmenopausal | Not applicable | Completed | Khyber Medical University Peshawar | 40 | 2025-10-01 | 2026-08-13 |
| Evaluation of Osteo-Buddy in Improving Osteoporosis Knowledge Osteo-Buddy, Usual Care - Osteoporosis Risk, Osteoporosis, Postmenopausal | Not applicable | Not yet recruiting | SingHealth Polyclinics | 80 | 2025-07-01 | 2025-07-01 |
| Effects of Cycle Therapy vs Sequential Therapy With Romosozumab and Denosumab in Postmenopausal Osteoporosis Patients Romosozumab followed by Denosumab, Romosozumab and Denosumab Cycle Therapy - Osteoporosis, Osteoporosis Postmenopausal | Phase 4 | Recruiting | National Taiwan University Hospital | 70 | 2025-04-08 | 2026-06-23 |
| Evaluation of a Decision Analysis Model in the DASH-Osteo Decision Aid. Decision aid with decision analysis model, Decision aid alone, Usual Care - Osteoporosis, Postmenopausal, Osteoporotic Fractures | Not applicable | Enrolling by invitation | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 114 | 2025-04-03 | 2025-08-13 |
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Osteoporosis (125) · Bone Diseases, Metabolic (45) · Motor Activity (11) · Osteoporotic Fractures (10) · Bone Diseases (8) · Fractures, Bone (7) · Musculoskeletal Diseases (6) · Diabetes Mellitus, Type 2 (5) · Sarcopenia (5) · Spinal Fractures (5) · Breast Neoplasms (4) · Hot Flashes (4) · Sclerosteosis (4) · Bone Resorption (3)
Metabolic Diseases (330) · Nutritional and Metabolic Diseases (330) · Musculoskeletal Diseases (324) · Bone Diseases (322) · Bone Diseases, Metabolic (285) · Osteoporosis (205) · Wounds and Injuries (21) · Pathological Conditions, Signs and Symptoms (20) · Fractures, Bone (14) · Behavior (13) · Signs and Symptoms (13) · Endocrine System Diseases (11) · Neurologic Manifestations (9) · Nervous System Diseases (8) · Glucose Metabolism Disorders (6)
Denosumab (46) · Teriparatide (35) · Alendronate (32) · Ibandronic Acid (28) · Risedronic Acid (23) · Zoledronic Acid (18) · Cholecalciferol (15) · romosozumab (15) · Raloxifene Hydrochloride (12) · Calcium (11) · Calcium Carbonate (11) · Vitamin D (11) · Exercise (8) · abaloparatide (7) · salmon calcitonin (5)
Eli Lilly and Company (25) · Amgen (24) · Hoffmann-La Roche (21) · Massachusetts General Hospital (10) · Sanofi (10) · Organon and Co (9) · GlaxoSmithKline (7) · Radius Health, Inc. (7) · Merck Sharp & Dohme LLC (5) · Warner Chilcott (5) · 424 General Military Hospital (4) · Bayer (4) · Novartis (4) · Novartis Pharmaceuticals (4) · Riphah International University (4)
United States (106) · Poland (36) · Canada (26) · Spain (26) · China (25) · Denmark (24) · Czechia (23) · France (22) · Italy (22) · Germany (21) · United Kingdom (21) · Belgium (20) · Hungary (19) · Turkey (Türkiye) (19) · Australia (17)
Benjamin Leder, MD (5) · Athanasios D Anastasilakis, MD, PhD (3) · Patricia Loranca-Moreno, M.D., M.Sc. (3) · Susan L Greenspan, MD (3) · Ahmed M Maged (2)
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