8 completed, 3 recruiting, 3 unknown, 1 available. 7 Phase 3, 5 Phase 2, 3 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 3, Recruiting 2, Unknown 2 |
| Phase 2 | 5 | Completed 3, Recruiting 2 |
| Not applicable | 3 | Completed 3 |
| Phase 4 | 1 | Unknown 1 |
Follow fluorocholine: new trials by email Literature Review of fluorocholine trials Research Report on fluorocholine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors 18F-FCH, NeuroEXPLORER - Primary Hyperparathyroidism, Parathyroid Cancer | Phase 2 / Phase 3 | Recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 193 | 2026-04-16 | 2026-10-29 |
| Prospective Comparative Study for Patients With Biochemical Recurrence Prostate Cancer Detecting by 18F-JK-PSMA-7 Radiopharmaceutical 18F-JK-PSMA-7, Radiopharmaceutical 18F-Fluorocholine - Prostate Cancer, 18F- Fluorocholine | Phase 3 | Unknown | ITEL Telecomunicazioni Srl | 106 | 2022-12-19 | 2024-05-22 |
| Choline-PET: Exploratory Study Assessing the Potential Role of F-choline PET Imaging in New and Emerging Indications F-choline intravenous injection - Lesion With Known or Suspected F-choline Uptake | Phase 3 | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 500 | 2022-08-01 | 2026-03-19 |
| Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma Fluorine-18 fluorocholine - Hepatocellular Carcinoma Non-resectable | Phase 2 | Recruiting | Queen's Medical Center | 80 | 2022-03-28 | 2026-08-12 |
| 18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid Adenomas 18F-Fluorocholine, Positron emission tomography (PET) - Hyperparathyroidism, Primary | Phase 3 | Completed | Thomas Hope | 139 | 2021-06-30 | 2026-04-29 |
| Combination PET With 18F-fluorodeoxyglucose (18F-FDG) and 18 F-choline in Patient With HCC PET-TDM with 18F-FDG + PET-TDM with 18F-fluorocholine - Hepatocellular Carcinoma | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 230 | 2020-07-17 | 2023-11-18 |
| 18F-fluorocholine and 18F-fluoride PET in Prostate Cancer 18F-fluorocholine - Prostate Cancer, Fluorocholine | Not applicable | Completed | Buddhist Tzu Chi General Hospital | 36 | 2018-02-01 | 2020-04-13 |
| 18F-Fluorocholine for the Detection of Parathyroid Adenomas 18F-Fluorocholine, Positron Emission Tomography (PET) - Hyperparathyroidism, Primary | Phase 2 / Phase 3 | Completed | Thomas Hope | 98 | 2016-09-21 | 2021-10-19 |
| The Safety and Efficacy of 18F-Fluoromethylcholine (18F-FCH) PET/CT in Prostate Cancer 18F-Fluoromethylcholine (18F-FCH) - Prostate Cancer | Phase 3 | Completed | Sir Mortimer B. Davis - Jewish General Hospital | 60 | 2016-09-01 | 2018-08-09 |
| 11C- and 18F-Choline PET/MR Imaging for Prostate Cancer Carbon C 11 Choline, Fluorine F 18 Choline, Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI) - Prostate Cancer | Phase 2 | Completed | University of California, San Francisco | 18 | 2015-04-09 | 2020-11-19 |
| To Evaluate the Efficacy and Safety of (18F-FCH) Comparing With (18F-FDG) for Detecting Hepatocellular Carcinoma 18F- fluorocholine, 18F- fluorodeoxyglucose - Hepatocellular Carcinoma, Liver Disease | Phase 3 | Unknown | National Taiwan University Hospital | 150 | 2014-02-01 | 2014-02-28 |
| 18F-FCH (Fluorocholine)-PET/MR in Staging of High-Risk Prostate Cancer Fluorocholine (18F-FCH) Injection, PET scan, Whole body MRI - Prostate Cancer | Not applicable | Completed | University Health Network, Toronto | 50 | 2013-12-01 | 2017-01-13 |
| Proton MR Spectroscopy and 18F-Fluorocholine PET for Breast Cancer Diagnosis 18F-FCH, Magnevist - Breast Cancer Diagnosis, Positron Emission Tomography | Phase 4 | Unknown | National Taiwan University Hospital | 80 | 2012-09-01 | 2016-02-04 |
| PET/CT in Diagnosing Patients With Liver Cancer Undergoing Surgical Resection Computed Tomography, 18F-fluoromethylcholine, Positron Emission Tomography - Adult Hepatocellular Carcinoma, Localized Resectable Adult Liver Carcinoma | Phase 2 | Completed | Queen's Medical Center | 64 | 2011-08-15 | 2018-09-26 |
| Expanded Access:18F-Fluorocholine for the Detection of Parathyroid Adenomas 18F-Fluorocholine (FCH), Positron emission tomography (PET) - Parathyroid Adenomas | Available | Thomas Hope | 2025-10-20 |
Prostatic Neoplasms (5) · Carcinoma, Hepatocellular (4) · Hyperparathyroidism, Primary (3) · Parathyroid Neoplasms (2) · Breast Neoplasms (1) · Disease (1) · Liver Diseases (1) · Multiple Endocrine Neoplasia Type 1 (1)
Thomas Hope (3) · National Taiwan University Hospital (2) · Queen's Medical Center (2) · Assistance Publique - Hôpitaux de Paris (1) · Buddhist Tzu Chi General Hospital (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · ITEL Telecomunicazioni Srl (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · University Health Network, Toronto (1) · University of California, San Francisco (1)
United States (6) · Canada (3) · Taiwan (3) · France (1) · Italy (1)
Thomas Hope, MD (3) · Albert J Chang, MD, PhD (1) · Daniel Juneau, MD (1) · Jane Wang, PhD (1) · Kai-Yuan Tzen, MD (1) · Sandi A Kwee, MD, PhD (1) · Sandi Kwee, MD (1) · Smita Jha, M.D. (1) · Ur Metser, MD (1) · Yu-Hung Chen, M.D. (1)
PMID 15840561, PMID 20800404, PMID 21350618, PMID 21844889, PMID 23559588, PMID 23797218, PMID 24072344, PMID 24207135, PMID 24920079, PMID 25203127, PMID 25411132, PMID 25447835, PMID 27363387, PMID 27513849, PMID 28518227, PMID 29315063, PMID 30027419, PMID 30174470, PMID 30389823, PMID 30448957, PMID 30507748, PMID 31324713, PMID 31516367, PMID 31836681, PMID 31836682, PMID 34895925, PMID 39987937
R01CA148708 (1), R01CA161209 (1), R01CA262460 (1)