52 completed, 20 unknown, 7 recruiting, 5 active not recruiting. 27 Not applicable, 13 Phase 2, 13 Phase 3, 9 Phase 4, 4 Phase 1.
Follow Hypocalcemia: new trials by email Literature Review of Hypocalcemia trials Research Report on Hypocalcemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ionized Calcium as a Severity Marker in Septic Shock Patients Sepsis, Septic Shock | Not yet recruiting | Assiut University | 160 | 2026-10-01 | 2026-09-10 | |
| NIRAF-Guided Parathyroid Identification During Thyroidectomy Wearable Near-Infrared Autofluorescence Imaging System - Hypocalcemia, Hypoparathyroidism | Not applicable | Not yet recruiting | Ss. Cyril and Methodius University of Skopje | 280 | 2026-06-01 | 2026-06-01 |
| Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia total thyroidectomy - Hypocalcemia After Total Thyroidectomy | Completed | Al Safwa University College | 123 | 2025-09-17 | 2025-10-08 | |
| Comparing PTeye-assisted Versus Conventional Total Thyroidectomy PTeye™ parathyroid detection system - Hypocalcemia, Parathyroid | Not applicable | Recruiting | The University of Hong Kong | 210 | 2025-09-16 | 2026-02-17 |
| WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-Making Near-Infrared Parathyroid Tissue Sensor Imaging (PTS), Rim-Preservation Technique, En-bloc Resection Technique - Hyperparathyroidism, Primary, Parathyroid Neoplasms | Not applicable | Not yet recruiting | Fujian Medical University | 120 | 2025-07-01 | 2025-06-29 |
| Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence Imaging ntra-operative Indocyanine Green (ICG) Fluorescence Quantification - Thyroid Surgery | Recruiting | Fujian Medical University | 210 | 2025-05-01 | 2025-07-15 | |
| Calcium Administration in Life-saving Management During Massive Hemorrhage calcium gluconate, Control: Placebo - Massive Hemorrhage, Trauma | Phase 2 / Phase 3 | Not yet recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 81 | 2025-05-01 | 2025-02-11 |
| Empiric Calcium in Massive Transfusion Calcium Gluconate - Hemorrhage, Trauma | Phase 3 | Withdrawn | University of California, Irvine | 2025-01-01 | 2026-03-30 | |
| Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults AMOR-1, Crystalline Calcium Carbonate - Hypoparathyroidism | Phase 2 | Active not recruiting | Amorphical Ltd. | 62 | 2024-12-15 | 2026-08-14 |
| COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C - Cardiopulmonary Failure, Myocardial Infarction (MI) | Enrolling by invitation | Peerbridge Health, Inc | 15000 | 2024-11-16 | 2025-01-08 | |
| Hypoglycemia Prevention and Awareness Program Hypoglycemia prevention and awareness program (HypoPAP) - Diabetes, Hypocalcemia | Not applicable | Active not recruiting | Merve DerviAYoAYlu | 62 | 2024-11-01 | 2025-01-15 |
| Therapeutic Effects of Oat-based Cereal on Fetomaternal Outcomes Among Hypocalcemic Antenatal Women Oat-Based porridge, Calcium & Vitamin D3 supplementation - Hypocalcemia, Pregnancy Complications Affecting Fetus (Diagnosis) | Not applicable | Completed | University of Lahore Hospital (ULH) | 192 | 2024-08-01 | 2026-08-12 |
| The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and Hypocalcaemia Dexamethasone, Normal saline - Voice Change, Hypocalcemia | Phase 2 | Unknown | Tseung Kwan O Hospital, Hong Kong | 100 | 2024-07-01 | 2024-07-09 |
| A Comparative Analysis of Hypocalcemia Incidence in Patients Undergoing Thyroidectomy: Ligasure vs Conventional Ligation of Vessels by Knot Tying Using Ligasure for heamostasis, Use of conventional knot tying technique for heamostasis - Hypocalcemia After Total Thyroidectomy, Hypocalcemia | Not applicable | Completed | Gulab Devi Hospital | 76 | 2024-04-20 | 2025-06-10 |
| PTH-independent Effects of Encaleret encaleret - Post-Surgical Hypoparathyroidism | Phase 2 | Completed | National Institute of Dental and Craniofacial Research (NIDCR) | 13 | 2023-09-01 | 2026-03-11 |
| Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients Calcium Gluconate, Calcium chloride - Postpartum Hemorrhage, Pregnancy Related | Early Phase 1 | Completed | Stanford University | 34 | 2023-08-19 | 2024-04-11 |
| Complications After Thyroid Surgeries: 10 Years' Experience Thyroidectomy - Thyroid | Completed | South Valley University | 241 | 2023-01-30 | 2023-10-24 | |
| Comparison of Liagure Safety in Thyroidectomy With Conventional Thyroidectomy liagsure device - Ligature; Hemorrhage, Recurrent Laryngeal Nerve Injuries | Not applicable | Unknown | Imam Mohammad ibn Saud Islamic University | 20 | 2023-01-15 | 2023-01-13 |
| Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 Encaleret, Standard of Care - Autosomal Dominant Hypocalcemia (ADH) | Phase 3 | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 67 | 2023-01-06 | 2026-07-29 |
| Effect of Preoperative High-dose Cholecalciferol in Prevention of Post-thyroidectomy Hypocalcaemia Cholecalciferol - Hypocalcemia | Not applicable | Unknown | Pak Emirates Military Hospital | 170 | 2022-11-01 | 2023-03-29 |
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Hypoparathyroidism (24) · Hyperparathyroidism, Secondary (9) · Thyroid Diseases (7) · Vitamin D Deficiency (7) · Renal Insufficiency, Chronic (5) · Hemorrhage (4) · Postoperative Complications (4) · Hypercalcemia (3) · Hypercalciuria (3) · Hypercalciuric Hypocalcemia, Familial (3) · Hyperparathyroidism (3) · Musculoskeletal Diseases (3) · Thyroid Neoplasms (3) · Thyroid Nodule (3)
Nutritional and Metabolic Diseases (94) · Water-Electrolyte Imbalance (94) · Calcium Metabolism Disorders (92) · Metabolic Diseases (92) · Endocrine System Diseases (43) · Parathyroid Diseases (35) · Pathological Conditions, Signs and Symptoms (26) · Pathologic Processes (22) · Urogenital Diseases (16) · Female Urogenital Diseases and Pregnancy Complications (14) · Male Urogenital Diseases (13) · Deficiency Diseases (12) · Female Urogenital Diseases (12) · Kidney Diseases (12) · Malnutrition (12)
Calcitriol (7) · Calcium (6) · Vitamin D (5) · Calcium Carbonate (4) · Calcium Gluconate (4) · Cholecalciferol (4) · etelcalcetide hydrochloride (4) · Dexamethasone (3) · Saline Solution (3) · Thyroidectomy (3) · Parathyroid Hormone (2) · Teriparatide (2) · Thymus Extracts (2) · alfacalcidol (2) · Antilymphocyte Serum (1)
Amgen (4) · Assiut University (3) · National Institutes of Health Clinical Center (CC) (3) · Calcilytix Therapeutics, Inc., a BridgeBio company (2) · Department of Medical Services Ministry of Public Health of Thailand (2) · Fujian Medical University (2) · Hôpital Européen Marseille (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Shire (2) · Sumitomo Pharma Switzerland GmbH (2) · University Hospital Sestre Milosrdnice (2) · Abbott (1) · Aix Marseille Université (1) · Al Safwa University College (1) · Amorphical Ltd. (1)
United States (29) · France (10) · Canada (8) · Italy (8) · Spain (7) · Germany (6) · Australia (5) · Belgium (5) · Denmark (5) · Egypt (5) · Israel (5) · Netherlands (5) · Poland (5) · United Kingdom (5) · China (4)
M. Louise Markert, MD, PhD (2) · Abdallah M Taha, MD (1) · Alvaro Sanabria, MD (1) · Anders OJ Bergenfelz, PhD (1) · Anna Grzegory, MD (1) · Asmaa Abdelmageed Muhammed, Lecturer (1) · Awais Amjad Malik, MBBS, FCPS (1) · Christian von Buchwald, MDSc, PhD (1) · David Brams, MD (1)
PMID 18035553, PMID 18424759, PMID 18557726, PMID 19066739, PMID 20236866, PMID 12605179, PMID 17284531, PMID 19117033, PMID 21565561, PMID 22090268, PMID 22994525, PMID 23607606, PMID 23702146, PMID 23914737, PMID 24948345, PMID 25777546, PMID 26050997, PMID 27647184, PMID 29280010, PMID 30327136, PMID 30859218, PMID 31281762, PMID 31494332, PMID 31693081, PMID 33084768, PMID 33484559, PMID 33631337, PMID 34374848, PMID 34473215, PMID 35945357, PMID 36018496, PMID 36853388, PMID 37223015, PMID 37758507, PMID 38027217, PMID 39077939, PMID 39282041, PMID 40172208, PMID 40711996, PMID 41712216, PMID 41847596, PMID 8156110
K12HD043494 (2), R01AI047040 (2), R01AI054843 (2), 2017 (1), 2018 (1), 2019 (1), R56AI047040 (1)