285 completed, 91 unknown, 59 recruiting, 27 not yet recruiting. 116 Not applicable, 86 Phase 2, 57 Phase 3, 57 Phase 4, 31 Phase 1.
Follow Calcium Metabolism Disorders: new trials by email Literature Review of Calcium Metabolism Disorders trials Research Report on Calcium Metabolism Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-Interleukin-6 (IL6) in Calciphylaxis Tocilizumab - Calciphylaxis | Phase 1 | Not yet recruiting | Boston Medical Center | 10 | 2027-09-01 | 2026-07-16 |
| Analysis of the Influence of Dialysis Fluid Composition on Vascular Calcification in Patients With Chronic Kidney Disease Undergoing Hemodialysis Citrate dialysate with magensium supplementation, Acetate dialysate - Vascular Calcification, Hemodialysis | Not applicable | Not yet recruiting | Hospital Clinic of Barcelona | 80 | 2027-01-02 | 2026-09-16 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients Ramipril tablet, Amlodipine tablet - Endothelial Dysfunction, End-Stage Renal Disease | Phase 3 | Not yet recruiting | Ain Shams University | 50 | 2026-11-01 | 2026-10-21 |
| Diagnostic Work-up of Nephrocalcinosis in Children Nephrocalcinosis | Not yet recruiting | Assiut University | 40 | 2026-10-20 | 2026-10-20 | |
| Tissue Validation of Mammographic Breast Arterial Calcification in Mastectomy Specimens Breast Cancer, Vascular Calcification | Not yet recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 100 | 2026-10-15 | 2026-10-15 | |
| Ionized Calcium as a Severity Marker in Septic Shock Patients Sepsis, Septic Shock | Not yet recruiting | Assiut University | 160 | 2026-10-01 | 2026-09-10 | |
| Osteoporosis & Renal Disease: Research in Primary Health Care Services Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA) - Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder | Not yet recruiting | Universidade do Porto | 622 | 2026-10-01 | 2026-09-30 | |
| Study of EPN-701 for the Treatment of Calciphylaxis EPN-701 (Oral), Placebo (Normal Saline) - Calciphylaxis | Phase 2 | Not yet recruiting | Sagar U. Nigwekar, MD, MMSc | 60 | 2026-10-01 | 2026-09-14 |
| Molecular Imaging to Identify Predictors of Aortic Valve Disease Activity AORTIC VALVE DISEASES, Calcification; Heart | Not yet recruiting | Massachusetts General Hospital | 100 | 2026-09-30 | 2026-09-16 | |
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Not yet recruiting | Martin Blomberg Jensen | 100 | 2026-09-01 | 2026-09-18 |
| Post-Marketing Clinical Study of High-Pressure Cutting Balloon High pressure cutting balloon, Non-cutting balloon - Coronary Artery Disease, Calcification | Not applicable | Recruiting | BrosMed Medical Co., Ltd | 280 | 2026-09-01 | 2026-09-22 |
| Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis intra-oral 3D optical impression - Osteogenesis Imperfecta, Rare Bone Disorders | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 240 | 2026-09-01 | 2026-06-24 |
| Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a) Setmelanotide - Pseudohypoparathyroidism Type 1a, Obesity | Phase 2 | Enrolling by invitation | Massachusetts General Hospital | 1 | 2026-07-21 | 2026-07-23 |
| Treatment Patterns, Biochemical Profiles and Clinical Outcomes in Adults With X-Linked Hypophosphatemia No treatment given - X-linked Hypophosphatemia (XLH) | Withdrawn | Novo Nordisk A/S | 2026-07-07 | 2026-08-28 | ||
| Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD Low-dose Colchicine at 0.5mg daily, Usual Care - Chronic Kidney Disease Mineral and Bone Disorder, Hypertension | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 60 | 2026-07-01 | 2026-06-22 |
| Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Femoral Stenting (SKYWARD Trans-Femoral IDE [Investigational Device Exemption] Study) Carotid Intravascular Lithotripsy - Carotid Artery Calcification, Carotid Artery Diseases | Not applicable | Not yet recruiting | Shockwave Medical, Inc. | 185 | 2026-07-01 | 2026-07-31 |
| Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis Patients Medium Cut-Off Hemodialysis Membrane, High-Flux Hemodialysis Membrane - End Stage Kidney Disease (ESKD), Hemodialysis | Not applicable | Active not recruiting | Gazi University | 30 | 2026-07-01 | 2026-09-14 |
| Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study) Carotid Intravascular Lithotripsy (IVL) - Carotid Artery Calcification, Carotid Artery Diseases | Not applicable | Recruiting | Shockwave Medical, Inc. | 185 | 2026-06-22 | 2026-10-15 |
| NIRAF-Guided Parathyroid Identification During Thyroidectomy Wearable Near-Infrared Autofluorescence Imaging System - Hypocalcemia, Hypoparathyroidism | Not applicable | Not yet recruiting | Ss. Cyril and Methodius University of Skopje | 280 | 2026-06-01 | 2026-06-01 |
Showing 20 of 535. Sign in to see all of them.
Hypocalcemia (94) · Calcinosis (89) · Vascular Calcification (81) · Chronic Kidney Disease-Mineral and Bone Disorder (73) · Renal Insufficiency, Chronic (62) · Hypercalcemia (50) · Familial Hypophosphatemic Rickets (49) · Kidney Failure, Chronic (37) · Rickets (36) · Hyperparathyroidism, Secondary (34) · Osteomalacia (34) · Hypoparathyroidism (32) · Vitamin D Deficiency (27) · Bone Diseases (26) · Hyperparathyroidism (23)
Nutritional and Metabolic Diseases (534) · Metabolic Diseases (528) · Musculoskeletal Diseases (223) · Urogenital Diseases (210) · Female Urogenital Diseases and Pregnancy Complications (209) · Male Urogenital Diseases (207) · Female Urogenital Diseases (206) · Urologic Diseases (204) · Pathological Conditions, Signs and Symptoms (199) · Nutrition Disorders (196) · Kidney Diseases (195) · Bone Diseases, Metabolic (194) · Bone Diseases (190) · Deficiency Diseases (190)
burosumab (22) · Cholecalciferol (20) · Calcitriol (18) · Vitamin D (14) · Cinacalcet (13) · sodium thiosulfate (12) · asfotase alfa (10) · Blood Specimen Collection (9) · Calcium (9) · Calcium Carbonate (8) · Ergocalciferols (7) · Sevelamer (7) · etelcalcetide hydrochloride (7) · paricalcitol (7) · Saline Solution (6)
Alexion Pharmaceuticals, Inc. (13) · Kyowa Kirin Co., Ltd. (12) · Amgen (9) · Hospices Civils de Lyon (9) · Mayo Clinic (8) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (8) · Assiut University (7) · Massachusetts General Hospital (7) · Kyowa Kirin, Inc. (6) · National Institute of Dental and Craniofacial Research (NIDCR) (6) · University of Aarhus (6) · Vanderbilt University Medical Center (6) · Yale University (6) · Columbia University (5) · Kyowa Kirin Pharmaceutical Development Ltd (5)
United States (176) · France (53) · Canada (37) · China (36) · United Kingdom (34) · Italy (33) · Germany (31) · Denmark (28) · Spain (23) · Netherlands (18) · Japan (16) · Belgium (15) · Australia (14) · Turkey (Türkiye) (14) · Poland (13)
Jaclyn Tamaroff, MD (3) · Smita Jha, M.D. (3) · Thomas Nickolas, MD, MS (3) · Alex Gold, MD (2) · Amy Zhang, PhD (2) · Craig Sherman, MD (2) · Ditte Hansen, MD, PhD (2) · Ditte Hansen, Medical doctor, professor (2) · Jing Chen, MD (2) · M. Louise Markert, MD, PhD (2)
PMID 39151033, PMID 40576086, PMID 26529632, PMID 32417537, PMID 32721016, PMID 32762706, PMID 34231877, PMID 39186385, PMID 40668552, PMID 40962182, PMID 18035553, PMID 18424759, PMID 18557726, PMID 19066739, PMID 20236866, PMID 22169620, PMID 23102518, PMID 25919461, PMID 27699270, PMID 33305842, PMID 36854566, PMID 38189593, PMID 10089993, PMID 10584989, PMID 10816185, PMID 11443763, PMID 12110413, PMID 12200646, PMID 12605179, PMID 12935835, PMID 12937218, PMID 14581387, PMID 14582032, PMID 15284307, PMID 15810001, PMID 15894595, PMID 15930998, PMID 15942915, PMID 15961949, PMID 16227647, PMID 16675931, PMID 16973975, PMID 17130273, PMID 17164301, PMID 17190895, PMID 17284531, PMID 17468488, PMID 17652219, PMID 18007136, PMID 18046319
R01CA212147 (3), 2018 (2), K12HD043494 (2), R01AI047040 (2), R01AI054843 (2), 1IK2CX000549-01 (1), 1RC1HD063562 (1), 1UL1TR001863-01 (1), 2008 (1), 2014 (1), 2017 (1), 2019 (1), K23DK101689 (1), K23DK136930 (1), N01CM00039 (1)