22 completed, 4 recruiting, 1 not yet recruiting, 1 terminated. 30 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 30 | Completed 22, Recruiting 4, Not yet recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Hyperparathyroidism, Primary: new trials by email Literature Review of Hyperparathyroidism, Primary trials Research Report on Hyperparathyroidism, Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism Scheduling Navigation, Without Scheduling Navigation - Hyperparathyroidism, Primary | Not applicable | Recruiting | University of Pennsylvania | 76 | 2026-10-01 | 2026-08-27 |
| NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary Hyperparathyroidism NIRAF-camera - Primary Hyperparathyroidism | Not applicable | Recruiting | The Cleveland Clinic | 80 | 2026-08-31 | 2026-09-11 |
| WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-Making Near-Infrared Parathyroid Tissue Sensor Imaging (PTS), Rim-Preservation Technique, En-bloc Resection Technique - Hyperparathyroidism, Primary, Parathyroid Neoplasms | Not applicable | Not yet recruiting | Fujian Medical University | 120 | 2025-07-01 | 2025-06-29 |
| Evaluation of the Role of Intraoperative Neuromonitoring(IONM) in Patients Undergoing Parathyroid Surgery for Solitary Parathyroid Adenoma INTRAOPERATIVE NEUROMONITORING - Evaluation of the Role of IONM in Minimally Invasive Parathyroidectomy Performed for Solitary Parathyroid Adenoma | Not applicable | Completed | Izmir Katip Celebi University | 100 | 2024-02-21 | 2026-09-23 |
| Autofluorescence in Surgery for Primary Hyperparathyroidism Surgery with autofluorescence - Hyperparathyroidism, Primary | Not applicable | Recruiting | Aarhus University Hospital | 100 | 2024-01-01 | 2025-01-29 |
| 18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Imaging for Localizing Diseased Parathyroid Glands in Primary Hyperparathyroidism Parathyroidectomy - Primary Hyperparathyroidism | Not applicable | Recruiting | Region Skane | 88 | 2023-01-01 | 2025-08-24 |
| Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy Parathyroid Eye (PTeye) - Parathyroid Diseases, Parathyroid Dysfunction | Not applicable | Completed | University of California, San Francisco | 79 | 2022-01-10 | 2025-12-15 |
| Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy PTeye, Standard of Care - Parathyroid Adenoma, Parathyroid Neoplasms | Not applicable | Completed | University of Michigan | 160 | 2021-12-01 | 2025-08-27 |
| Gait and Balance Parameters Before and After Parathyroidectomy in Patients With Primary Hyperparathyroidism gait analysis - Primary Hyperparathyroidism | Not applicable | Completed | Recep Tayyip Erdogan University Training and Research Hospital | 40 | 2021-10-17 | 2023-12-05 |
| Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment Cholecalciferol - Postmenopausal Osteoporosis, Postmenopause | Not applicable | Completed | Hospital Regional 1o de Octubre | 47 | 2021-04-29 | 2022-05-06 |
| Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy NIRAF Detection Technology - Parathyroid Adenoma, Parathyroid Neoplasms | Not applicable | Completed | Vanderbilt-Ingram Cancer Center | 160 | 2020-03-13 | 2024-05-13 |
| Preoperative Localization Strategies in Primary Hyperparathyroidism Contrast-enhanced ultrasound - Primary Hyperparathyroidism | Not applicable | Completed | Odense University Hospital | 172 | 2019-09-05 | 2022-04-14 |
| FCH PET/MRI Parathyroid Localization [F-18]-FCH PET/MRI - 18F-fluorocholine, Positron-Emission Tomography | Not applicable | Completed | University Health Network, Toronto | 47 | 2018-04-03 | 2023-12-07 |
| Comparison of Cervical Ultrasound and Echoscintigraphy for Preoperative Localization Diagnosis in Primary Hyperparathyroidism cervical ultrasound - Primary Hyperparathyroidism | Not applicable | Unknown | CHU de Reims | 100 | 2017-10-05 | 2018-07-30 |
| Effect of Parathyroidectomy on Cardiovascular Health Early parathyroidectomy group (EPTX-group) - Primary Hyperparathyroidism | Not applicable | Completed | University of Aarhus | 69 | 2017-02-03 | 2019-09-30 |
| Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism Laboratory Biomarker Analysis, Parathyroidectomy - Parathyroid Gland Adenoma, Primary Hyperparathyroidism | Not applicable | Completed | Roswell Park Cancer Institute | 6 | 2016-05-12 | 2021-08-12 |
| Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid Surgery Conventional (dual-phase) SPECT/CT, Multi-phase SPECT/CT, Conventional minimally-invasive radio-guided parathyroidectomy - Primary Hyperparathyroidism, Thyroid Disease | Not applicable | Completed | University Hospital Ostrava | 100 | 2016-05-01 | 2022-12-07 |
| Bone Microarchitectural Database Constitution From HR-pQCT Device in Clinical Situation Potentially Associated With Bone Loss HR-pQCT, DEXA, pQCT - Osteoporosis, Bone Loss | Not applicable | Terminated | Centre Hospitalier Universitaire de Saint Etienne | 287 | 2015-03-18 | 2024-02-06 |
| Preliminary Study Concerning the Validity of Parathyroid Exploration on a CZT Camera Tomoscintigraphic parathyroid imaging on a CZT camera - Primary Hyperparathyroidism | Not applicable | Completed | Centre Hospitalier Universitaire de Besancon | 45 | 2014-09-04 | 2024-09-19 |
| Primary Hyperparathyroidism: Short-term Calcimimetics Treatment - Relevance for Parathyroid Surgery Decisions? Cinacalcet, parathyroid adenomectomy - Primary Hyperparathyroidism | Not applicable | Completed | Karolinska University Hospital | 110 | 2014-06-01 | 2024-08-06 |
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Parathyroid Neoplasms (7) · Hyperparathyroidism (4) · Bone Diseases, Metabolic (3) · Hypercalcemia (3) · Osteoporosis (3) · Osteoporosis, Postmenopausal (2) · Parathyroid Diseases (2) · Adenoma (1) · Anorexia Nervosa (1) · Arthritis, Rheumatoid (1) · Atherosclerosis (1) · Bone Diseases (1) · Endocrine Gland Neoplasms (1) · Hyperparathyroidism, Secondary (1)
Endocrine System Diseases (30) · Parathyroid Diseases (28) · Hyperparathyroidism (26) · Metabolic Diseases (8) · Nutritional and Metabolic Diseases (8) · Head and Neck Neoplasms (7) · Neoplasms (7) · Neoplasms by Site (7) · Endocrine Gland Neoplasms (6) · Musculoskeletal Diseases (5) · Bone Diseases (4) · Calcium Metabolism Disorders (4) · Water-Electrolyte Imbalance (4) · Mental Disorders (2) · Nervous System Diseases (2)
Parathyroidectomy (3) · Cholecalciferol (2) · Alendronate (1) · Calcium Carbonate (1) · Cinacalcet (1) · Congresses as Topic (1) · Gait Analysis (1) · Interviews as Topic (1) · Intraoperative Neurophysiological Monitoring (1) · Standard of Care (1) · Surgical Procedures, Operative (1) · Walking (1)
Karolinska University Hospital (2) · Region Skane (2) · Aarhus University Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · CHU de Reims (1) · Centre Hospitalier Universitaire de Besancon (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Columbia University (1) · Fujian Medical University (1) · Hospital Regional 1o de Octubre (1) · Izmir Katip Celebi University (1) · M.D. Anderson Cancer Center (1) · Odense University Hospital (1) · Rambam Health Care Campus (1) · Recep Tayyip Erdogan University Training and Research Hospital (1)
United States (8) · France (5) · Sweden (5) · Denmark (4) · Turkey (Türkiye) (2) · Canada (1) · China (1) · Czechia (1) · Israel (1) · Italy (1) · Mexico (1) · Poland (1)
Anders Bergenfelz, MD, Ass Prof (1) · Anders OJ Bergenfelz, MD, PhD (1) · Carmen C Solorzano, MD, FACS (1) · Constantin Ungureanu, MD (1) · Inga-Lena Nilsson, M.D., Ph.D (1) · Inga-Lena Nilsson, MD, Ass prof (1) · Inga-Lena Y Nilsson, MD, PhD (1) · Jadwiga W Szymczak, PhD, MD (1) · John P Bilezikian, M.D. (1) · Lars Rejnmark, M.D, PhD (1)
PMID 40668552, PMID 20035529, PMID 20395857, PMID 24026893, PMID 24115138, PMID 25414430, PMID 26435425, PMID 28522130, PMID 30860588, PMID 31595982, PMID 37052913, PMID 42817602
R01CA212147 (3), R01DK032333 (1)