5 completed, 2 recruiting, 1 terminated, 1 unknown. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 5, Recruiting 2, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Hyperparathyroidism, Primary: new trials by email Literature Review of Hyperparathyroidism, Primary trials Research Report on Hyperparathyroidism, Primary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bisphosphonate Prior to Parathyroidectomy in Primary Hyperparathyroidism Zoledronic acid 4 mg, Natriumklorid 9 mg/ml, Fresenius Kabi - Primary Hyperparathyroidism | Phase 4 | Recruiting | University of Aarhus | 140 | 2025-03-01 | 2026-10-01 |
| Calcitonin Pre-treatment to Improve SPECT-CT Sensitivity Calcitonin - Primary Hyperparathyroidism, Hypercalcemia | Phase 4 | Recruiting | Joseph Sferra | 37 | 2019-05-29 | 2024-09-19 |
| Osteoporosis in Primary Hyperparathyroidism Denosumab 60 MG/ML Prefilled Syringe [Prolia], Zoledronic Acid - Primary Hyperparathyroidism, Osteoporosis | Phase 4 | Unknown | University Medical Centre Ljubljana | 40 | 2019-05-08 | 2022-11-04 |
| Denosumab in Primary Hyperparathyroidism Denosumab, Placebo - Primary Hyperparathyroidism | Phase 4 | Terminated | Columbia University | 8 | 2012-01-01 | 2022-11-02 |
| Vitamin D Repletion in Primary Hyperparathyroidism 10,000 IU Vitamin D3, Placebo, Vitamin D - Primary Hyperparathyroidism, Vitamin D Deficiency | Phase 4 | Completed | Columbia University | 9 | 2011-10-01 | 2019-04-16 |
| Systematic Treatment After Successful Surgical Treatment for Primary Hyperparathyroidism With Strontium Ranelate Strontium Ranelate + Ca/Vitamin-D, Placebo - Primary Hyperparathyroidism, Osteopenia | Phase 4 | Completed | Medical University of Vienna | 63 | 2010-09-01 | 2015-01-21 |
| Evaluation of a Cincalcet Suppression Test cinacalcet, cinacalcet dose 1, cinacalcet dose 2 - Parathyroid Hormone Suppression Test With Cinacalcet | Phase 4 | Completed | University Hospital, Rouen | 36 | 2010-04-01 | 2026-04-16 |
| Efficacy of Cinacalcet in the Control of Primary Hyperparathyroidism cinacalcet, Alendronate - Hyperparathyroidism, Primary, Osteoporosis | Phase 4 | Completed | Istituto Auxologico Italiano | 22 | 2008-05-01 | 2015-04-15 |
| The Effects of Alendronate After Cure of Primary Hyperparathyroidism Alendronate 70mg weekly - Hyperparathyroidism | Phase 4 | Withdrawn | Columbia University | 2006-07-01 | 2011-11-16 | |
| A Study of an Investigational Medication for Severe Primary Hyperparathyroidism or Parathyroid Cancer AMG 073 - Hyperparathyroidism, Parathyroid Neoplasms | Phase 4 | Completed | Amgen | 46 | 2001-04-01 | 2013-05-08 |
Osteoporosis (4) · Bone Diseases, Metabolic (3) · Hypercalcemia (3) · Hyperparathyroidism (2) · Disease (1) · Fractures, Bone (1) · Parathyroid Neoplasms (1) · Vitamin D Deficiency (1)
Endocrine System Diseases (10) · Parathyroid Diseases (10) · Hyperparathyroidism (8) · Metabolic Diseases (7) · Nutritional and Metabolic Diseases (7) · Bone Diseases (6) · Musculoskeletal Diseases (6) · Bone Diseases, Metabolic (3) · Calcium Metabolism Disorders (3) · Water-Electrolyte Imbalance (3) · Avitaminosis (1) · Deficiency Diseases (1) · Endocrine Gland Neoplasms (1) · Head and Neck Neoplasms (1) · Malnutrition (1)
Cinacalcet (3) · Alendronate (2) · Denosumab (2) · Zoledronic Acid (2) · Calcitonin (1) · Cholecalciferol (1) · Saline Waters (1) · Vitamin D (1) · salmon calcitonin (1) · strontium ranelate (1)
Columbia University (3) · Amgen (1) · Istituto Auxologico Italiano (1) · Joseph Sferra (1) · Medical University of Vienna (1) · University Hospital, Rouen (1) · University Medical Centre Ljubljana (1) · University of Aarhus (1)
United States (4) · Austria (1) · Denmark (1) · France (1) · Italy (1) · Slovenia (1)
Anne F Cailleux, MD (1) · Bruno Niederle, Prof., MD (1) · Jean Marc J Kuhn, MD (1) · John P Bilezikian, MD (1) · Joseph Sferra, MD (1) · Lars Rejnmark, Professor (1) · Shonni J Silverberg, MD (1) · Shonni J. Silverberg, MD (1) · Tomaz Kocjan, MD, PhD (1)
PMID 17666472, PMID 19470620, PMID 20943783, PMID 25645432
2008 (1), 2023 (1), R01DK032333 (1), R01DK084986 (1)