838 completed, 373 unknown, 281 recruiting, 100 terminated. 527 Not applicable, 314 Phase 2, 149 Phase 1, 134 Phase 3, 107 Phase 4.
Follow Thyroid Diseases: new trials by email Literature Review of Thyroid Diseases trials Research Report on Thyroid Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mapping Patient Decision-making in Thyroid Cancer Decision navigation tool - Thyroid Cancer | Not applicable | Not yet recruiting | University of California, Los Angeles | 50 | 2028-04-01 | 2026-07-24 |
| Discontinuation of Low-Dose Levothyroxine in Older Adults With Subclinical Hypothyroidism Levothyroxine Pill, Placebo - Hypothyroidism | Phase 4 | Not yet recruiting | Spyridoula Maraka | 138 | 2027-10-01 | 2026-08-26 |
| Pre-Clinic Visit Online Education for Thyroid Cancer THRIVE, ACS "After a Thyroid Cancer Diagnosis" Flyer - Thyroid Cancer | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 60 | 2027-08-01 | 2026-09-01 |
| Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease MHB018A injection - Thyroid Eye Disease (TED) | Phase 3 | Not yet recruiting | Minghui Pharmaceutical (Hangzhou) Ltd | 219 | 2027-07-01 | 2026-06-04 |
| Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns Blood test - Congenital Hypothyroidism | Not yet recruiting | University Hospital, Lille | 1600 | 2027-03-01 | 2026-05-22 | |
| Vitamin E Add-On Therapy, Thyroid Function & Oxidative Stress in Levothyroxine-Treated Hypothyroidism vitamin E, placebo - Hypothyroidism | Not applicable | Enrolling by invitation | Bangladesh Medical University | 74 | 2027-02-01 | 2026-08-25 |
| Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules Diagnostic DNA Methylation Signature - Thyroid Gland Nodule | Recruiting | City of Hope Medical Center | 22 | 2027-01-01 | 2026-06-02 | |
| Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis Gluten-free, casein-free, low-glycemic-index diet - Thyroid Autoimmune Disease, Hashimoto's Thyroiditis | Not applicable | Not yet recruiting | University of Barcelona | 60 | 2027-01-01 | 2026-11-04 |
| Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer Dabrafenib, Trametinib, Pembrolizumab - Anaplastic Thyroid Carcinoma, Thyroid Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 12 | 2026-12-31 | 2026-10-21 |
| Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial Internet-Based Intervention, Interview, Questionnaire Administration - Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm | Not applicable | Not yet recruiting | University of Michigan Rogel Cancer Center | 142 | 2026-12-01 | 2026-10-15 |
| MYTP01 for Immune-Mediated Diseases MYTP01, MYTP01 Placebo - IgA Nephropathy, Kidney Transplant Recipients | Not applicable | Not yet recruiting | Zhejiang Provincial People's Hospital | 160 | 2026-12-01 | 2026-11-04 |
| 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer 68Ga-DOTA-TATE PET Scan, Amino acid infusions, 177Lu-DOTA-EB-TATE - Thyroid Cancer | Phase 1 / Phase 2 | Not yet recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 18 | 2026-11-10 | 2026-11-05 |
| Thyroid-Stimulating Hormone Receptor (TSHR) Blockade With REGN24493 in Adult Participants With Graves' Disease (GD) REGN24493, Placebo - Graves' Disease | Phase 1 | Not yet recruiting | Regeneron Pharmaceuticals | 45 | 2026-11-02 | 2026-10-06 |
| T4/T3 Therapy in Hypothyroidism Liothyronine (L-T3), Levothyroxine Sodium (LT4) Tablets, Liothyronine (LT3) placebo - Hypothyroidism Primary | Phase 2 | Not yet recruiting | University of Pennsylvania | 60 | 2026-11-01 | 2026-08-20 |
| Sacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRAP) Sacituzumab Tirumotecan - Recurrent Adenoid Cystic Carcinoma, Adenoid Cystic Carcinoma Metastatic | Phase 2 | Not yet recruiting | National Cancer Centre, Singapore | 68 | 2026-11-01 | 2026-07-15 |
| Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO) Atorvastatin - Graves Disease, Graves Disease (Basedow's Disease) | Phase 2 | Not yet recruiting | Region Skane | 554 | 2026-11-01 | 2026-10-20 |
| Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery Transcartilage needle electrode recording, Endotracheal tube surface electrode recording - Thyroid Diseases, Recurrent Laryngeal Nerve Injury | Not applicable | Not yet recruiting | Marmara University | 100 | 2026-11-01 | 2026-10-30 |
| Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma | Not yet recruiting | Marmara University | 90 | 2026-11-01 | 2026-11-02 | |
| Bethesda Classification and Risk Stratification in Differentiated Thyroid Carcinoma Differentiated Thyroid Carcinoma, Papillary Thyroid Carcinoma | Not yet recruiting | Assiut University | 100 | 2026-10-26 | 2026-10-05 | |
| AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' Disease Glandy HYPER (AI-based monitoring software), Methimazole - Hyperthyroidism, Graves Disease | Not applicable | Not yet recruiting | THYROSCOPE INC. | 30 | 2026-10-20 | 2026-10-05 |
Showing 20 of 1853. Sign in to see all of them.
Thyroid Neoplasms (722) · Graves Ophthalmopathy (197) · Hypothyroidism (195) · Thyroid Nodule (186) · Thyroid Cancer, Papillary (185) · Graves Disease (160) · Hyperthyroidism (110) · Neoplasms (79) · Breast Neoplasms (76) · Head and Neck Neoplasms (70) · Adenocarcinoma, Follicular (62) · Goiter (61) · Melanoma (60) · Carcinoma, Non-Small-Cell Lung (57)
Endocrine System Diseases (1832) · Neoplasms by Site (962) · Endocrine Gland Neoplasms (935) · Neoplasms (918) · Head and Neck Neoplasms (880) · Immune System Diseases (436) · Autoimmune Diseases (374) · Neoplasms by Histologic Type (352) · Goiter (329) · Eye Diseases (325) · Orbital Diseases (318) · Neoplasms, Glandular and Epithelial (311) · Exophthalmos (304) · Hyperthyroidism (291)
Thyroxine (90) · Thyroidectomy (31) · Iodine-131 (30) · Triiodothyronine (25) · Methimazole (24) · Methylprednisolone (22) · Magnetic Resonance Spectroscopy (21) · lenvatinib (20) · Blood Specimen Collection (17) · Thyrotropin Alfa (17) · teprotumumab (15) · trametinib (15) · Saline Solution (14) · pembrolizumab (14) · Sorafenib (13)
Assiut University (45) · National Cancer Institute (NCI) (45) · Memorial Sloan Kettering Cancer Center (26) · M.D. Anderson Cancer Center (21) · National Taiwan University Hospital (21) · Fujian Medical University (17) · Sun Yat-sen University (17) · Amgen (16) · Fudan University (16) · Mayo Clinic (15) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (15) · Yonsei University (15) · Seoul National University Hospital (14) · University of Pisa (14) · Chinese PLA General Hospital (12)
United States (511) · China (303) · Italy (134) · France (127) · South Korea (97) · Turkey (Türkiye) (78) · Spain (76) · Germany (73) · United Kingdom (70) · Canada (68) · Denmark (62) · Poland (53) · Egypt (51) · Taiwan (51) · Australia (46)
Marcin Barczynski, MD, PhD (7) · Joanna Klubo-Gwiezdzinska, M.D. (6) · Yukun Luo (5) · Kiyohiko Mabuchi, M.D. (4) · Naris Nilubol, M.D. (4) · Yunwei Wei (4) · Alan Ho, MD, PhD (3)
PMID 37934000, PMID 27797318, PMID 40341199, PMID 40668552, PMID 18299459, PMID 19556464, PMID 19850691, PMID 22402975, PMID 25209242, PMID 26462967, PMID 27240885, PMID 28487349, PMID 29343557, PMID 31838007, PMID 32612576, PMID 33570641, PMID 33720068, PMID 33768488, PMID 36657661, PMID 37171634, PMID 37786277, PMID 37816266, PMID 40086048, PMID 40844370, PMID 41066062, PMID 10427152, PMID 10517721, PMID 10634372, PMID 10683005, PMID 10782451, PMID 10873993, PMID 11119728, PMID 11129808, PMID 11172193, PMID 11239487, PMID 11334386, PMID 11442004, PMID 11535445, PMID 11580992, PMID 11875733, PMID 11879213, PMID 11932302, PMID 12050214, PMID 12225640, PMID 12390993, PMID 12541136, PMID 12608932, PMID 12656658, PMID 12660642, PMID 12727961
2023 (10), 2025 (8), 2015 (7), 2016 (5), P30CA015083 (5), 2017 (4), 2019 (4), N01CM62207 (4), 2005 (3), 2014 (3), N01CM00099 (3), N01CM62201 (3), N01CM62206 (3), P30CA008748 (3), P30CA016672 (3)