9 terminated. 9 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Terminated 9 |
| Phase 1 | 2 | Terminated 2 |
| Phase 3 | 1 | Terminated 1 |
Follow Hyperglycemia: new trials by email Literature Review of Hyperglycemia trials Research Report on Hyperglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant Alpelisib, Fulvestrant, Metformin XR - Breast Cancer | Phase 2 | Terminated | Novartis Pharmaceuticals | 2 | 2022-04-06 | 2024-10-09 |
| Pioglitazone Treatment for Hyperglycemic Acute Ischemic Stroke Pioglitazone 45 mg, Placebo oral tablet - Stroke, Acute, Hyperglycemia | Phase 1 / Phase 2 | Terminated | Milton S. Hershey Medical Center | 1 | 2020-09-01 | 2022-09-15 |
| Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes Insulin - Type 1 Diabetes, Hyperglycemia, Postprandial | Phase 1 / Phase 2 | Terminated | Washington University School of Medicine | 1 | 2020-02-13 | 2022-10-07 |
| A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure LIK066, Placebo, Empagliflozin - Diabetes Mellitus and Heart Failure | Phase 2 | Terminated | Novartis Pharmaceuticals | 125 | 2017-07-25 | 2019-08-28 |
| Interventional Bioremediation of Microbiota in Metabolic Syndrome Vancomycin, Placebo, Neomycin - Pre-Diabetes | Phase 2 | Terminated | University of Minnesota | 12 | 2016-06-01 | 2023-02-22 |
| Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin Metformin, Sugar pill - Insulin Resistance, Hypermetabolism | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 36 | 2012-11-01 | 2019-11-29 |
| Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity Metformin, Orlistat, Topiramate - Obesity, Metabolic Syndrome X | Phase 2 | Terminated | University of Iowa | 128 | 2011-03-01 | 2026-03-12 |
| Sitagliptin in Cystic Fibrosis-Related Diabetes Sitagliptin, Placebo - Cystic Fibrosis | Phase 2 | Terminated | University of British Columbia | 3 | 2010-09-01 | 2014-03-06 |
| Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects losartan, hydrochlorothiazide - Pre-hypertension, Pre-diabetes | Phase 2 | Terminated | Sir Mortimer B. Davis - Jewish General Hospital | 1 | 2007-03-01 | 2015-05-19 |
Glucose Intolerance (3) · Diabetes Mellitus (2) · Hypertension (2) · Obesity (2) · Breast Neoplasms (1) · Burns (1) · Cystic Fibrosis (1) · Diabetes Mellitus, Type 1 (1) · Diabetes Mellitus, Type 2 (1) · Dyslipidemias (1) · Heart Failure (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Insulin Resistance (1) · Metabolic Syndrome (1)
Glucose Metabolism Disorders (9) · Metabolic Diseases (9) · Nutritional and Metabolic Diseases (9) · Cardiovascular Diseases (4) · Vascular Diseases (4) · Endocrine System Diseases (3) · Body Weight (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2) · Hyperinsulinism (2) · Nervous System Diseases (2) · Nutrition Disorders (2) · Overnutrition (2) · Overweight (2)
Metformin (2) · Alpelisib (1) · Clindamycin (1) · Dipeptidyl-Peptidase IV Inhibitors (1) · Fecal Microbiota Transplantation (1) · Fulvestrant (1) · Insulin (1) · Losartan (1) · Neomycin (1) · Orlistat (1) · Pioglitazone (1) · Sitagliptin Phosphate (1) · Sugars (1) · Topiramate (1) · Vancomycin (1)
Novartis Pharmaceuticals (2) · Milton S. Hershey Medical Center (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · The University of Texas Medical Branch, Galveston (1) · University of British Columbia (1) · University of Iowa (1) · University of Minnesota (1) · Washington University School of Medicine (1)
United States (7) · Canada (3) · Argentina (1) · Austria (1) · Belgium (1) · Bulgaria (1) · Croatia (1) · Czechia (1) · Denmark (1) · Germany (1) · Hungary (1) · Ireland (1) · Italy (1) · Malaysia (1) · Mexico (1)
Alexander Khoruts, MD (1) · David N Herndon, MD (1) · Ernesto L. Schiffrin, MD, PhD (1) · Gary L Pierce, PhD (1) · Graydon Meneilly, MD (1) · Janet McGill, MD (1) · Kerstin Bettermann, MD, PhD (1)
2016 (1)