72 completed, 8 unknown, 7 terminated, 2 active not recruiting. 91 Phase 3, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 91 | Completed 72, Unknown 8, Terminated 7, Active not recruiting 2, Withdrawn 2 |
| Phase 2 | 13 | Completed 12, Terminated 1 |
Follow Hyperglycemia: new trials by email Literature Review of Hyperglycemia trials Research Report on Hyperglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy Alpha lipoic acid, Roflumilast - Type 2 Diabetes (Adult Onset), Diabetic Neuropathies | Phase 3 | Completed | Tanta University | 60 | 2022-08-01 | 2023-11-22 |
| Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH. Berberine, Placebo - Metabolic Syndrome, HIV-1-infection | Phase 3 | Unknown | Hospital Civil de Guadalajara | 40 | 2021-04-01 | 2021-04-26 |
| Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial Dapagliflozin 5mg, Placebo - Diabetes Mellitus, Type 1 | Phase 3 | Active not recruiting | The Hospital for Sick Children | 100 | 2020-12-11 | 2023-11-21 |
| Novolog vs. Fiasp Insulin in Non-critically Ill Hospitalized Patients With Type 2 Diabetes Mellitus Insulin glargine, NovoLog, Insulin Fiasp - Type 2 Diabetes Treated With Insulin | Phase 3 | Completed | Boston Medical Center | 137 | 2020-12-07 | 2024-03-19 |
| Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19 Linagliptin tablet, Insulin - Hyperglycemia, Covid19 | Phase 3 | Completed | Hospital Regional de Alta Especialidad del Bajio | 70 | 2020-08-01 | 2021-03-23 |
| Clinical Trial of Efficacy and Safety of Subetta in the Treatment of Impaired Glucose Tolerance Subetta, Placebo - Impaired Glucose Tolerance | Phase 3 | Completed | Materia Medica Holding | 538 | 2018-10-10 | 2021-02-04 |
| Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS Liraglutide Pen Injector [Saxenda], Placebo Liraglutide Pen Injector - Pre Diabetes, Polycystic Ovary Syndrome | Phase 3 | Completed | Woman's | 88 | 2018-09-26 | 2021-06-07 |
| Tight Versus Liberal Blood Glucose Control in Adult Critically Ill Patients Insulin - Critical Illness, Hyperglycemia | Phase 3 | Active not recruiting | KU Leuven | 9230 | 2018-09-18 | 2023-06-05 |
| Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition Sacubitril/Valsartan 200mg (blinded), Valsartan 160mg (blinded) - Diabetes Mellitus, Type 2, Pre-diabetic | Phase 3 | Withdrawn | University of Pennsylvania | 2018-06-01 | 2026-09-21 | |
| Safety and Feasibility Evaluation of the APS APP Artificial Pancreas App - Type 1 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Sansum Diabetes Research Institute | 6 | 2018-02-28 | 2018-09-05 |
| Control of Hyperglycemia After Cardiac Surgery: CHyCS Trial Insulin - Hyperglycemia | Phase 3 | Terminated | University of Sao Paulo | 500 | 2017-01-01 | 2022-11-04 |
| At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run Adaptation CGM and Insulin Pump, Closed-Loop Control System - Type 1 Diabetes Mellitus | Phase 3 | Completed | Sansum Diabetes Research Institute | 32 | 2016-02-01 | 2016-10-14 |
| Insulin Glargine Versus Regular Insulin Based Regimens in Glycemic Control After Acute Stroke Insulin Glargine, Regular Insulin - Acute Stroke, Hyperglycemia | Phase 3 | Unknown | National Taiwan University Hospital | 120 | 2015-12-01 | 2016-08-19 |
| L-arginine and Brown Adipose Tissue L-arginine, Placebo - Adipose Tissue, Brown, Glucose Intolerance | Phase 3 | Unknown | Maastricht University Medical Center | 26 | 2014-11-01 | 2014-11-14 |
| Benefit of IQP-VV-102 in Reducing Postprandial Glucose Level in Overweight Caucasian Subjects Dose 1 of IQP-VV-102, Dose 2 of IQP-VV-102, Placebo - Prediabetes, Hyperglycemia | Phase 3 | Completed | InQpharm Group | 27 | 2014-06-01 | 2015-11-10 |
| Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar Levels Study dietary supplement (PreCrea 600 mg capsules), Placebo - Diabetes Mellitus, Pre-Diabetes | Phase 3 | Completed | Joe Fenn | 210 | 2013-11-01 | 2015-05-18 |
| Insulin Therapy for the Prevention of New Onset Diabetes After Transplantation Prospective Study in Non-Diabetic De Novo Kidney Transplant Recipients Human insulin isophane, Humulin N (Eli Lilly), Standard of care, Insulin lispro, Humalog (Eli Lilly) in insulin pump - Hyperglycemia | Phase 3 | Completed | Medical University of Vienna | 263 | 2012-11-21 | 2019-02-19 |
| Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin Metformin, Sugar pill - Insulin Resistance, Hypermetabolism | Phase 2 / Phase 3 | Terminated | The University of Texas Medical Branch, Galveston | 36 | 2012-11-01 | 2019-11-29 |
| Nutritional Requirement for the Severe Trauma Patients high caloric nutritional supplement, low caloric nutritional supplement - Trauma | Phase 3 | Unknown | Asan Medical Center | 61 | 2012-11-01 | 2013-01-04 |
| Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes Metformin 500 mg bid, Metformin 1000 mg bid, Empagliflozin low dose qd - Diabetes Mellitus, Type 2, Hyperglycemia | Phase 3 | Completed | Boehringer Ingelheim | 1413 | 2012-10-01 | 2016-02-19 |
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Glucose Intolerance (39) · Diabetes Mellitus, Type 2 (28) · Diabetes Mellitus (18) · Insulin Resistance (14) · Hypoglycemia (10) · Metabolic Syndrome (10) · Cardiovascular Diseases (6) · Prediabetic State (6) · Diabetes Mellitus, Type 1 (5) · Obesity (5) · Hypertension (4) · Coronary Artery Disease (3) · Critical Illness (3) · Dyslipidemias (3)
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Metformin (13) · Insulin Glargine (8) · lixisenatide (8) · Insulin (7) · Rosiglitazone (7) · alogliptin (4) · dapagliflozin (4) · Arginine (3) · Exercise (3) · Insulin Aspart (3) · Insulin Lispro (3) · Liraglutide (3) · Pioglitazone (3) · Ramipril (3) · Standard of Care (3)
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PMID 39963952, PMID 27267268, PMID 27319011, PMID 31956422, PMID 38770818, PMID 11832527, PMID 15793249, PMID 16075050, PMID 16738506, PMID 16855264, PMID 16980380, PMID 16997664, PMID 17310047, PMID 17583796, PMID 17898990, PMID 17909087, PMID 17947341, PMID 18184958, PMID 18268075, PMID 18544707, PMID 18839134, PMID 19114908, PMID 19131464, PMID 19171717, PMID 19318384, PMID 19477351, PMID 19559824, PMID 19636533, PMID 19640291, PMID 20573639, PMID 20634175, PMID 20634176, PMID 20682687, PMID 21118562, PMID 21428766, PMID 21515846, PMID 21733058, PMID 21852284, PMID 22059803, PMID 22082239, PMID 22179955, PMID 22215178, PMID 22291490, PMID 22419732, PMID 22424822, PMID 22432104, PMID 22442395, PMID 22442396, PMID 22443353, PMID 22564709
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